KEGG ENZYME: 1.1.2.6

ENZYME: 1.1.2.6

Entry

EC 1.1.2.6                  Enzyme

Name

polyvinyl alcohol dehydrogenase (cytochrome);
PVA dehydrogenase;
PVADH

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With a cytochrome as acceptor

Sysname

polyvinyl alcohol:ferricytochrome-c oxidoreductase

Reaction(IUBMB)

polyvinyl alcohol + ferricytochrome c = oxidized polyvinyl alcohol + ferrocytochrome c + H+ [RN:R03136]

Reaction(KEGG)

R03136

Substrate

polyvinyl alcohol [CPD:C00980];
ferricytochrome c [CPD:C00125]

Product

oxidized polyvinyl alcohol [CPD:C01166];
ferrocytochrome c [CPD:C00126];
H+ [CPD:C00080]

Comment

A quinoprotein. The enzyme is involved in bacterial polyvinyl alcohol degradation. Some Gram-negative bacteria degrade polyvinyl alcohol by importing it into the periplasmic space, where it is oxidized by polyvinyl alcohol dehydrogenase, an enzyme that is coupled to the respiratory chain via cytochrome c. The enzyme contains a pyrroloquinoline quinone cofactor.

History

EC 1.1.2.6 created 1989 as EC 1.1.99.23, transferred 2010 to EC 1.1.2.6

Orthology

K05889

polyvinyl alcohol dehydrogenase (cytochrome)

Genes

XFA:

XF_2259

XFT:

PD_1299

XFN:	XfasM23_1384

XFF:	XFLM_00585

XFL:	P303_06185

XFS:	D934_06040

XTW:	AB672_07465

XCC:

XCC4080

XCB:

XC_4171

XCA:	xcc-b100_4282(mxaF2)

XCP:

XCR_0167

XCV:

XCV4300

XAX:

XACM_4071

XAC:

XAC4199

XCI:	XCAW_00095

XCT:	J151_04381

XCJ:	J158_04334

XCU:	J159_04330

XCN:	J169_04378

XCW:	J162_04336

XCR:	J163_04331

XCM:	J164_04331

XCF:	J172_04371

XFU:	XFF4834R_chr40700

XAO:	XAC29_21160

XOM:	XOO0301(XOO0301)

XOO:

XOO0329

XOP:

PXO_02746

XOY:	AZ54_23465

XOR:

XOC_0353

XOZ:	BE73_22640

XSA:	SB85_06375

XTN:	FD63_06065

XFR:	BER92_01075

XVE:	BJD12_11700

XPE:	BJD13_17990

XHR:	XJ27_14710

XGA:	BI317_01715

XPH:	XppCFBP6546_13360(XppCFBP6546P_13360)

XAN:	AC801_20920

XAR:	XB05_15910

XHY:	FZ025_21115

XTH:	G4Q83_12040

XEU:	XSP_003948

XHD:	LMG31886_43030(pvaA)

XPR:	MUG10_11230

XAG:	HEP73_02938

XDY:	NYR95_22165

XAS:	HEP74_02769

KAK:	Kalk_14285

PSPI:

PS2015_1317 PS2015_1347

PAEW:

KIH87_12105

ZAL:	AZF00_04145

OSG:	BST96_13570 BST96_14780 BST96_16125

HJA:	BST95_07100

HALC:

EY643_15230

KIM:	G3T16_17020

AFUS:

EYZ66_08615

LSH:	CAB17_18600

BCT:

GEM_3393

BANN:

JFN94_16570

BAEN:

L3V59_27155

BCAI:

K788_0004339

DOE:	DENOEST_0328 DENOEST_1442

EBA:	p2A321(pvaA)

BJA:	bll5504(bll5504)

BJU:	BJ6T_42530

BJP:	RN69_20665

BRAD:

BF49_6141

BRK:	CWS35_01350

BOT:	CIT37_26850

BSYM:

CIT39_18860

BARH:

WN72_45780

BVZ:	BRAD3257_5552(pvaA)

BEL:	BE61_75900

BSEP:

HAP48_0010140

BQB:	J4P68_0029515

BBAN:

J4G43_033040

BCAN:

BcanWSM471_24315

BAUT:

QA635_31440

BBRA:

QA636_32990

BPAH:

QA639_11630

BRAZ:

LRP30_11400

PZU:

PHZ_c0057

PHB:	HYN04_08910

NPP:	PP1Y_Mpl7012

NOT:	C7W88_18110

SPHP:

LH20_00830 LH20_22430

SGI:	SGRAN_2681(pvadh)

SWI:

Swit_1323

SPHD:

HY78_19955

SPPH:

KFK14_08110

SLAA:

EUU25_15930

PARJ:

J4G78_07990

ANH:	A6F65_02146(pvaA)

ADO:	A6F68_02640(pvaA)

ERF:	FIU90_05160(pvaA)

NCB:	C0V82_25705

SUR:	STAUR_3610

AGE:	AA314_09129

SCL:

sce5403

SCU:	SCE1572_16470 SCE1572_48810

PTRI:

KDC22_18130

NBR:	O3I_001310

NTP:	CRH09_14355

NOZ:	DMB37_02095

NAH:	F5544_04375 F5544_29340

NIE:	KV110_15645

SPIN:

KV203_18520

SGF:	HEP81_07900

AGLA:

OIE69_01260

LSE:	F1C12_12190

MRG:	SM116_09425

ICA:	Intca_0327

TED:	U5C87_12450

AGRA:

AGRA3207_002444 AGRA3207_005569

ACTQ:

OG417_54035

MHAI:

OHB01_25115

AMYC:

CU254_27705

AAB:	A4R43_37700

AMYY:

YIM_40365(pvaA)

SESP:

BN6_35770 BN6_42600

SSYI:

EKG83_15725 EKG83_23805

KUT:	JJ691_34260(pvadh)

KPHY:

AOZ06_12405 AOZ06_38375

LED:	BBK82_29305

MCAB:

HXZ27_15905

AIH:	Aiant_25840

ACTL:

L3i22_083840

PLAB:

C6361_22955

PLAT:

C6W10_31785

PSUU:

Psuf_080790

NFL:	COO91_00281

PLON:

Pla110_26560

GMA:	AciX8_3775

TRS:	Terro_3165

TALB:

FTW19_16340

EDA:	GWR55_16290

SUS:

Acid_5713

ABAC:

LuPra_02536(pvaA)

MICA:

P0L94_08025

FGG:	FSB75_12825

SLI:

Slin_2985

SPIR:

CWM47_18820

SPIK:

EXU85_28000

SFOL:

H3H32_23665

PRHO:

PZB74_14235

MSZ:	MSSIH_3519

MSW:	MSSIT_3580

STO:

STK_11640

SOH:	D1869_04380

MTEN:

GWK48_09485

AMAN:

B6F84_03900

» show all

Reference

1 [PMID:3513704]

Authors

Shimao M, Ninomiya K, Kuno O, Kato N, Sakazawa C.

Title

Existence of a novel enzyme, pyrroloquinoline quinone-dependent polyvinyl alcohol dehydrogenase, in a bacterial symbiont, Pseudomonas sp. strain VM15C.

Journal

Appl Environ Microbiol 51:268-75 (1986)
DOI:10.1128/AEM.51.2.268-275.1986

Reference

2 [PMID:16347841]

Authors

Shimao M, Onishi S, Kato N, Sakazawa C.

Title

Pyrroloquinoline Quinone-Dependent Cytochrome Reduction in Polyvinyl Alcohol-Degrading Pseudomonas sp. Strain VM15C.

Journal

Appl Environ Microbiol 55:275-278 (1989)
DOI:10.1128/AEM.55.2.275-278.1989

Reference

3 [PMID:18343342]

Authors

Mamoto R, Hu X, Chiue H, Fujioka Y, Kawai F

Title

Cloning and expression of soluble cytochrome c and its role in polyvinyl alcohol degradation by polyvinyl alcohol-utilizing Sphingopyxis sp. strain 113P3.

Journal

J Biosci Bioeng 105:147-51 (2008)
DOI:10.1263/jbb.105.147

Reference

4 [PMID:16804170]

Authors

Hirota-Mamoto R, Nagai R, Tachibana S, Yasuda M, Tani A, Kimbara K, Kawai F

Title

Cloning and expression of the gene for periplasmic poly(vinyl alcohol) dehydrogenase from Sphingomonas sp. strain 113P3, a novel-type quinohaemoprotein alcohol dehydrogenase.

Journal

Microbiology 152:1941-9 (2006)
DOI:10.1099/mic.0.28848-0

Sequence

[ag:BAD95543]

Reference

5 [PMID:18214469]

Authors

Hu X, Mamoto R, Fujioka Y, Tani A, Kimbara K, Kawai F

Title

The pva operon is located on the megaplasmid of Sphingopyxis sp. strain 113P3 and is constitutively expressed, although expression is enhanced by PVA.

Journal

Appl Microbiol Biotechnol 78:685-93 (2008)
DOI:10.1007/s00253-008-1348-y

Reference

6 [PMID:19590867]

Authors

Kawai F, Hu X

Title

Biochemistry of microbial polyvinyl alcohol degradation.

Journal

Appl Microbiol Biotechnol 84:227-37 (2009)
DOI:10.1007/s00253-009-2113-6

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