KEGG ENZYME: 1.1.3.12

ENZYME: 1.1.3.12

Entry

EC 1.1.3.12                 Enzyme

Name

pyridoxine 4-oxidase;
pyridoxin 4-oxidase;
pyridoxol 4-oxidase

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With oxygen as acceptor

Sysname

pyridoxine:oxygen 4-oxidoreductase

Reaction(IUBMB)

pyridoxine + O2 = pyridoxal + H2O2 [RN:R01711]

Reaction(KEGG)

R01711

Substrate

pyridoxine [CPD:C00314];
O2 [CPD:C00007]

Product

pyridoxal [CPD:C00250];
H2O2 [CPD:C00027]

Comment

A flavoprotein. Can also use 2,6-dichloroindophenol as an acceptor.

History

EC 1.1.3.12 created 1972, modified 1976

Pathway

ec00750

Vitamin B6 metabolism

ec01100

Metabolic pathways

ec01120

Microbial metabolism in diverse environments

Orthology

K18607

pyridoxine 4-oxidase

Genes

MLO:

mll6785

MLN:	A9174_14005

MCI:	Mesci_2014

MCIC:

A4R28_16605

MAM:	Mesau_02077

MESW:

A9K65_010510

MESM:

EJ066_21210

MESP:

C1M53_04640

MHUA:

MCHK_0406

MJR:	EB229_14120

MERD:

EB233_10970

MMEI:

LRP31_23315

OCH:	CES85_3502(pno)

PLEO:

OHA_1_03156(pno)

HDI:	HDIA_0247(pno)

MEY:	TM49_03740

MMED:

Mame_00118(pno)

AUZ:	Sa4125_23970

CEH:	CEW89_08875

CON:	TQ29_16085

PALW:

PSAL_024180(pno)

HTQ:	FRZ44_40440

HADH:

FRZ61_38600

CPHY:

B5808_02080

HUM:	DVJ78_00575

HEA:	HL652_14720

NAEI:

GCM126_31080

» show all

Reference

1 [PMID:5769992]

Authors

Sundaram TK, Snell EE.

Title

The bacterial oxidation of vitamin B6. V. The enzymatic formation of pyridoxal and isopyridoxal from pyridoxine.

Journal

J Biol Chem 244:2577-84 (1969)

Other DBs

ExplorEnz - The Enzyme Database:

1.1.3.12

IUBMB Enzyme Nomenclature:

1.1.3.12

ExPASy - ENZYME nomenclature database:

1.1.3.12

UM-BBD (Biocatalysis/Biodegradation Database):

1.1.3.12

BRENDA, the Enzyme Database:

1.1.3.12

CAS:	37250-82-1

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