KEGG ENZYME: 1.1.99.13

ENZYME: 1.1.99.13

Entry

EC 1.1.99.13                Enzyme

Name

glucoside 3-dehydrogenase (acceptor);
D-glucoside 3-dehydrogenase (ambiguous);
D-aldohexopyranoside dehydrogenase (ambiguous);
D-aldohexoside:(acceptor) 3-oxidoreductase;
thuA (gene name);
thuB (gene name);
glucoside 3-dehydrogenase

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With unknown physiological acceptors

Sysname

D-aldohexoside:acceptor 3-oxidoreductase

Reaction(IUBMB)

sucrose + acceptor = 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor [RN:R00808]

Reaction(KEGG)

R00808 > R00807 R06233(G);
(other) R01680 R06219(G)

Substrate

sucrose [CPD:C00089];
acceptor [CPD:C00028]

Product

3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside [CPD:C05731];
reduced acceptor [CPD:C00030]

Comment

The enzymes from members of the Rhizobiaceae family (such as Agrobacterium tumefaciens) act on disaccharides that contain a glucose moiety at the non-reducing end, such as sucrose, trehalose, leucrose, palatinose, trehalulose, and maltitol, forming the respective 3'-keto derivatives. cf. EC 1.1.2.11, glucoside 3-dehydrogenase (cytochrome c).

History

EC 1.1.99.13 created 1972, modified 2022

Pathway

ec00500

Starch and sucrose metabolism

Reference

1 [PMID:16042015]

Authors

Jensen JB, Ampomah OY, Darrah R, Peters NK, Bhuvaneswari TV.

Title

Role of trehalose transport and utilization in Sinorhizobium meliloti--alfalfa interactions.

Journal

Mol Plant Microbe Interact 18:694-702 (2005)
DOI:10.1094/MPMI-18-0694

Reference

2 [PMID:23772075]

Authors

Ampomah OY, Avetisyan A, Hansen E, Svenson J, Huser T, Jensen JB, Bhuvaneswari TV.

Title

The thuEFGKAB operon of rhizobia and agrobacterium tumefaciens codes for transport of trehalose, maltitol, and isomers of sucrose and their assimilation through the formation of their 3-keto derivatives.

Journal

J Bacteriol 195:3797-807 (2013)
DOI:10.1128/JB.00478-13

Reference

3 [PMID:24142427]

Authors

Ampomah OY, Jensen JB.

Title

The trehalose utilization gene thuA ortholog in Mesorhizobium loti does not influence competitiveness for nodulation on Lotus spp.

Journal

World J Microbiol Biotechnol 30:1129-34 (2014)
DOI:10.1007/s11274-013-1527-6

Other DBs

ExplorEnz - The Enzyme Database:

1.1.99.13

IUBMB Enzyme Nomenclature:

1.1.99.13

ExPASy - ENZYME nomenclature database:

1.1.99.13

BRENDA, the Enzyme Database:

1.1.99.13

CAS:

9031-74-7

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (12)   
   KEGG COMPOUND (8)   
   KEGG GLYCAN (4)   
Chemical reaction (6)   
   KEGG REACTION (5)   
   KEGG RCLASS (1)   
Protein sequence (12)   
   UniProt (7)   
   RefSeq(pep) (5)   
DNA sequence (23)   
   RefSeq(nuc) (11)   
   GenBank (6)   
   EMBL (6)   
All databases (55)   

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