KEGG ENZYME: 1.1.99.21

ENZYME: 1.1.99.21

Entry

EC 1.1.99.21                Enzyme

Name

D-sorbitol dehydrogenase (acceptor);
D-sorbitol:(acceptor) 1-oxidoreductase

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With unknown physiological acceptors

Sysname

D-sorbitol:acceptor 1-oxidoreductase

Reaction(IUBMB)

D-sorbitol + acceptor = L-sorbose + reduced acceptor [RN:R01697]

Reaction(KEGG)

R01697 > R02925

Substrate

D-sorbitol [CPD:C00794];
acceptor [CPD:C00028]

Product

L-sorbose [CPD:C00247];
reduced acceptor [CPD:C00030]

Comment

A flavoprotein (FAD).

History

EC 1.1.99.21 created 1989

Pathway

ec00051

Fructose and mannose metabolism

ec01100

Metabolic pathways

Orthology

K08261

D-sorbitol dehydrogenase (acceptor)

Genes

LCIC:

INQ41_12750

GKD:	K6Q96_22670

PST:	PSPTO_0363(polS)

PSYI:

MME58_24620

PCUC:

PSH97_15100

HAHH:

O5O45_19925

CCAG:

SR908_10730

HEL:

HELO_2488

HSV:	HNO53_07010

HBH:	E4T21_18355

HSX:	HNO51_06360

HTX:	EKK97_07475

COBE:

CLAM6_11490

COBB:

H2O77_05980

SAJS:

QO259_13090

MRZ:	KDW95_00050

CRZ:	D1345_14600

CHAE:

CH06BL_30710

AQS:	DKK66_17340

RSO:	RSc2147(sorD)

RSE:

F504_2103

RPU:	CDC45_10950

RNC:	GO999_06140

BMA:

BMA0330

BMV:	BMASAVP1_A0628

BML:	BMA10229_A2462

BMN:	BMA10247_0076

BMAL:

DM55_1725(polS)

BMAE:

DM78_269(polS)

BMAQ:

DM76_1701(polS)

BMAI:

DM57_2356

BMAF:

DM51_125

BMAZ:

BM44_2898(polS)

BMAB:

BM45_648

BPS:

BPSL0826

BPM:	BURPS1710b_1031(sdh)

BPL:	BURPS1106A_0872

BPD:	BURPS668_0868

BPR:	GBP346_A0797

BPSE:

BDL_1201(polS)

BPSM:

BBQ_2622(polS)

BPSU:

BBN_2745(polS)

BPSD:

BBX_3148(polS)

BPZ:	BP1026B_I2725

BPQ:	BPC006_I0862

BPK:	BBK_680(polS)

BPSH:

DR55_294(polS)

BPSA:

BBU_1354(polS)

BPSO:

X996_3376(polS)

BUT:

X994_1910

BTE:

BTH_I0692

BTQ:	BTQ_710(polS)

BTJ:	BTJ_1734(polS)

BTZ:	BTL_3012(polS)

BTD:	BTI_2995(polS)

BTV:	BTHA_3229(polS)

BTHE:

BTN_1700(polS)

BTHM:

BTRA_3324(polS)

BTHA:

DR62_1887

BTHL:

BG87_3204

BOK:	DM82_218(polS)

BOC:

BG90_806

BUU:	WS70_04135

BSAV:

WS86_14845

BHG:	I6G56_05195

BUD:	AQ610_14985

BVI:	Bcep1808_2712

BVE:

AK36_1310

BUR:	Bcep18194_A5929

BCM:	Bcenmc03_2622

BCH:	Bcen2424_2598

BCJ:

BCAL2811

BCEN:

DM39_2682(polS)

BCEW:

DM40_229(polS)

BCEO:

I35_2668

BAM:

Bamb_2646

BAC:	BamMC406_2514

BMJ:	BMULJ_02561(gutB)

BMU:

Bmul_0699

BMK:	DM80_2367(polS)

BMUL:

NP80_2739

BCT:

GEM_0835

BCED:

DM42_2471(polS)

BDL:

AK34_491

BPYR:

ABD05_03035

BCON:

NL30_26060

BUB:

BW23_2296

BSTG:

WT74_13805

BANN:

JFN94_13330

BARI:

NLX30_15180

BAEN:

L3V59_14940

BGL:	bglu_1g29520

BGU:

KS03_403

BUG:	BC1001_2896

BGF:	BC1003_2832

BGD:	bgla_1g32960

BGO:	BM43_795(polS)

BUK:

MYA_2359

BUL:

BW21_3137

BGP:	BGL_1c30960

BPLA:

bpln_1g29980

BURK:

DM992_06980

BXE:

Bxe_A0719

BPH:

Bphy_0489

BGE:	BC1002_2507

BPY:	Bphyt_3247

PMEG:

FNZ07_29835

PTRO:

G5S35_11685

PGIS:

I6I06_15175

PACP:

FAZ97_11465

PACS:

FAZ98_11115

PEW:	KZJ38_20075

PDIO:

PDMSB3_3649(polS)

PBRY:

NDK50_17325

PSAA:

QEN71_02585

PKF:	RW095_31880

PPAI:

E1956_06045

CABA:

SBC2_06780(polS_1)

CABK:

NK8_05700

TVL:	FAZ95_03805

TCAR:

U0034_13500

AAA:

Acav_0908

VAP:	Vapar_1113

VPE:	Varpa_1196

RUG:	QC826_00045

GLC:	JQN73_19105

ETB:	N7L95_14670

MLO:

mll4921

RHI:	NGR_c24700(smoS)

SFH:	SFHH103_02335

SFD:	USDA257_c49010(polS)

SAME:

SAMCFNEI73_Ch2809(smoS)

RLE:

RL0650

RLT:	Rleg2_0269

RLG:

Rleg_0298

RLS:	HB780_11275

RAW:	NE851_13235

RLW:	RlegWSM1455_01400

ARA:	Arad_12179 Arad_8191(smoS)

RBW:	RLCC275e_01360

RIF:	U5G49_000283

XDI:	EZH22_02050

SIT:	TM1040_0427

PLCG:

RVY76_16180

PSEW:

JHW44_06765

AMAQ:

GO499_03780

LCK:	HN018_04230

HADH:

FRZ61_26920

BHUI:

LOK74_11095

BRUM:

NDK47_23200

PBK:	Back11_55830(fabG_8)

MSEO:

MSEO_20530

SLON:

LGI35_01325

ARHD:

VSH64_28420

MTAR:

DF168_00276(polS_1)

MCOS:

GM418_25875

HALR:

EFA46_011410

HSAL:

JMJ58_23290

» show all

Reference

Authors

Shinagawa, E. and Ameyama, M.

Title

Purification and characterization of D-sorbitol dehydrogenase from membrane of Gluconobacter suboxydans var-alpha.

Journal

Agric Biol Chem 46:135-141 (1982)

Other DBs

ExplorEnz - The Enzyme Database:

1.1.99.21

IUBMB Enzyme Nomenclature:

1.1.99.21

ExPASy - ENZYME nomenclature database:

1.1.99.21

BRENDA, the Enzyme Database:

1.1.99.21

CAS:	86178-94-1

DBGET integrated database retrieval system