KEGG   ENZYME: 1.1.99.32
Entry
EC 1.1.99.32                Enzyme                                 
Name
L-sorbose 1-dehydrogenase;
SDH (ambiguous)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With unknown physiological acceptors
Sysname
L-sorbose:acceptor 1-oxidoreductase
Reaction(IUBMB)
L-sorbose + acceptor = 1-dehydro-L-sorbose + reduced acceptor [RN:R09551]
Reaction(KEGG)
R09551
Substrate
L-sorbose [CPD:C00247];
acceptor [CPD:C00028]
Product
1-dehydro-L-sorbose [CPD:C19679];
reduced acceptor [CPD:C00030]
Comment
The product, L-sorbosone, is an intermediate in bacterial 2-keto-L-gulonic-acid formation. The activity of this membrane-bound enzyme is stimulated by Fe(III) or Co2+ but is inhibited by Cu2+. The enzyme is highly specific for L-sorbose as other sugars, such as glucose, mannitol and sorbitol, are not substrates. Phenazine methosulfate and DCIP can act as artificial acceptors.
History
EC 1.1.99.32 created 2008
Reference
1
  Authors
Sugisawa, T., Hoshino, T., Nomura, S. and Fujiwara, A.
  Title
Isolation and characterization of membrane-bound L-sorbose dehydrogenase from Gluconobacter melanogenus UV10.
  Journal
Agric Biol Chem 55:363-370 (1991)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.99.32
IUBMB Enzyme Nomenclature: 1.1.99.32
ExPASy - ENZYME nomenclature database: 1.1.99.32
BRENDA, the Enzyme Database: 1.1.99.32

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