Entry
Name
chloridazon-catechol dioxygenase;
5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone 1,2-oxidoreductase (decyclizing)
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
BRITE hierarchy
Sysname
5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone 1,2-oxidoreductase (ring-opening)
Reaction(IUBMB)
5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone + O2 = 5-amino-4-chloro-2-(2-hydroxymuconoyl)-3(2H)-pyridazinone [RN:
R04602 ]
Reaction(KEGG)
Substrate
5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone [CPD:
C04798 ];
O2 [CPD:
C00007 ]
Product
5-amino-4-chloro-2-(2-hydroxymuconoyl)-3(2H)-pyridazinone [CPD:
C05155 ]
Comment
An iron protein, requiring additional Fe2+. Not identical with EC
1.13.11.1 (catechol 1,2-dioxygenase), EC
1.13.11.2 (catechol 2,3-dioxygenase) or EC
1.13.11.5 (homogentisate 1,2-dioxygenase). Involved in the breakdown of the herbicide chloridazon.
History
EC 1.13.11.36 created 1984
Reference
Authors
Muller R, Haug S, Eberspacher J, Lingens F.
Title
[Catechol 2,3-dioxygenase from pyrazon-degrading bacteria (author's transl)]
Journal
Hoppe Seylers Z Physiol Chem 358:797-805 (1977)
Reference
Authors
Muller R, Schmitt S, Lingens F.
Title
A novel non-heme iron-containing dioxygenase. Chloridazon-catechol dioxygenase from Phenylobacterium immobilis DSM 1986.
Journal
Other DBs