Entry
Name
carlactone synthase;
CCD8 (gene name);
MAX4 (gene name);
NCED8 (gene name)
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
BRITE hierarchy
Sysname
9-cis-10'-apo-beta-carotenal:oxygen oxidoreductase (14,15-cleaving, carlactone-forming)
Reaction(IUBMB)
9-cis-10'-apo-beta-carotenal + 2 O2 = carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal [RN:
R10558 ]
Reaction(KEGG)
Substrate
Product
carlactone [CPD:
C20693 ];
(2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal [CPD:
C20694 ]
Comment
Requires Fe2+. The enzyme participates in a pathway leading to biosynthesis of strigolactones, plant hormones involved in promotion of symbiotic associations known as arbuscular mycorrhiza. Also catalyses EC
1.13.11.70 , all-trans-10'-apo-beta-carotenal 13,14-cleaving dioxygenase, but 10-fold slower.
History
EC 1.13.11.69 created 2012
Pathway
ec01110 Biosynthesis of secondary metabolites
Orthology
K17913 carlactone synthase / all-trans-10'-apo-beta-carotenal 13,14-cleaving dioxygenase
Genes
RPHI : 132733202 132740861
CSAT : 104716888 104721542 104729987
BNA : 106371158 106372794 106375326
CIC : CICLE_v100080502m CICLE_v10010609mg
GHI : 107897099 107900521 107901528 107953845
HSYR : 120114869 120192424
GMX : 100794831(CCD8) 100814148
VVO : 131654774 131660047 131660078
LJA : Lj1g3v2068760.1(Lj1g3v2068760.1)
QSA : O6P43_015496 O6P43_019476
MSYL : 126605834 126631671
CMAX : 111492518 111496443
CPEP : 111799272 111805686
PALZ : 118030684 118053670
CILL : 122317316 122319391
NTA : 107812793(MAX4) 107821949
SIND : 105156117 105165056
SSPL : 121778526 121780680 121781645 121781646 121781647
SHIS : 125189856 125210458 125211935
ECAD : 122583226 122583924 122586050
CCAV : 112520444 112521686
CQI : 110683157 110705573 110728350
MING : 122072068 122089718
DOSA : Os01t0566500-01(Os01g0566500) Os01t0746400-00(Os01g0746400)
ATS : 109738648 109753493 109753519 109758391
TDC : 119271872 119271874 119271875 119279309 119281469 119357533
TAES : 123056732 123058519 123065607 123067325 123074700 123133128 123191449
TUA : 125530689 125540847 125548561
LPER : 127316308 127343829
LRD : 124656146 124663088 124704073
SBI : 8057987 8062181 8064382
SITA : 101763948 101767361 101767759 101774274
SVS : 117855476 117855776 117858388 117866430
PVIR : 120672308 120674971 120684890 120708023 120708024
PHAI : 112894589 112894614 112903092
ZOF : 121999968 122003597 122016439 122048030
SMO : SELMODRAFT_127411(MAX4-2) SELMODRAFT_173016(MAX4-1)
CRE : CHLRE_02g073900v5 CHLRE_02g073950v5 CHLRE_08g365851v5
VCN : VOLCADRAFT_107173 VOLCADRAFT_108590 VOLCADRAFT_108622 VOLCADRAFT_108677
» show all
Taxonomy
Reference
Authors
Sorefan K, Booker J, Haurogne K, Goussot M, Bainbridge K, Foo E, Chatfield S, Ward S, Beveridge C, Rameau C, Leyser O
Title
MAX4 and RMS1 are orthologous dioxygenase-like genes that regulate shoot branching in Arabidopsis and pea.
Journal
Sequence
Reference
Authors
Schwartz SH, Qin X, Loewen MC
Title
The biochemical characterization of two carotenoid cleavage enzymes from Arabidopsis indicates that a carotenoid-derived compound inhibits lateral branching.
Journal
Sequence
Reference
Authors
Alder A, Jamil M, Marzorati M, Bruno M, Vermathen M, Bigler P, Ghisla S, Bouwmeester H, Beyer P, Al-Babili S
Title
The path from beta-carotene to carlactone, a strigolactone-like plant hormone.
Journal
Sequence
Other DBs