KEGG ENZYME: 1.13.11.82

ENZYME: 1.13.11.82

Entry

EC 1.13.11.82               Enzyme

Name

8'-apo-carotenoid 13,14-cleaving dioxygenase;
NACOX1 (gene name)

Class

Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen

Sysname

8'-apo-beta-carotenal:oxygen 13,14-dioxygenase (bond-cleaving)

Reaction(IUBMB)

8'-apo-beta-carotenal + O2 = 13-apo-beta-carotenone + 2,6-dimethyldeca-2,4,6,8-tetraenedial [RN:R11052]

Reaction(KEGG)

R11052

Substrate

8'-apo-beta-carotenal [CPD:C19728];
O2 [CPD:C00007]

Product

13-apo-beta-carotenone [CPD:C20696];
2,6-dimethyldeca-2,4,6,8-tetraenedial [CPD:C21078]

Comment

Isolated from the bacterium Novosphingobium aromaticivorans. It is less active with 4'-apo-beta-carotenal and gamma-carotene.

History

EC 1.13.11.82 created 2015

Orthology

K21822

8'-apo-carotenoid 13,14-cleaving dioxygenase

Genes

ACD:	AOLE_09020

AWU:	BEN71_01460

ACHI:

CDG60_05985

PAQM:

E0F26_03290

RGU:	A4W93_24915

MRD:	Mrad2831_6035

MOR:

MOC_3704

MAQU:

Maq22A_2p40185

MPHY:

MCBMB27_02697

METX:

A3862_15320

MMES:

MMSR116_02675

CSE:

Cseg_2406

NAR:

Saro_3580

NOG:	GKE62_03835

SAL:

Sala_1698

SPHK:

SKP52_06875

SPHP:

LH20_08885

SMAG:

AN936_04740

SMAZ:

LH19_16255

STER:

AOA14_13140

SGI:	SGRAN_3085

SPHQ:

BWQ93_00785

SPHO:

C3E99_10800

SPHX:

E5675_07820

SINA:

KNJ79_06250

SPHU:

SPPYR_2343

SLAN:

GV829_14185

SPAP:

H3Z74_23130

SPAI:

FPZ24_05250

SMOR:

LHA26_17895

SCAB:

LZK98_09310

SRAD:

LLW23_02470

SPHG:

AZE99_01830

SFLA:

SPHFLASMR4Y_02006

SPHY:

CHN51_03745

PALG:

HFP57_02260

PARP:

HFP51_03360

PARJ:

J4G78_12160

PHAO:

HF685_13020

SPHS:

ETR14_05980

AMX:	AM2010_818

PMAS:

NCF86_05030

ADO:	A6F68_02114

EFV:	CHH26_08820

QCI:	NCF85_05280

QSO:	IRL76_05010

ERR:	DVR09_09300

EMV:	HQR01_08985

LCK:	HN018_26190

SPIQ:

OHA34_00320

ACTR:

Asp14428_14950

DHI:	LH044_15405

» show all

Reference

1 [PMID:22711425]

Authors

Kim YS, Seo ES, Oh DK

Title

Characterization of an apo-carotenoid 13,14-dioxygenase from Novosphingobium aromaticivorans that converts beta-apo-8'-carotenal to beta-apo-13-carotenone.

Journal

Biotechnol Lett 34:1851-6 (2012)
DOI:10.1007/s10529-012-0969-5

Sequence

[nar:Saro_3580]

Other DBs

ExplorEnz - The Enzyme Database:

1.13.11.82

IUBMB Enzyme Nomenclature:

1.13.11.82

ExPASy - ENZYME nomenclature database:

1.13.11.82

BRENDA, the Enzyme Database:

1.13.11.82

DBGET integrated database retrieval system