KEGG ENZYME: 1.14.13.16

ENZYME: 1.14.13.16

Entry

EC 1.14.13.16               Enzyme

Name

cyclopentanone monooxygenase;
cyclopentanone oxygenase

Class

Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

Sysname

cyclopentanone,NADPH:oxygen oxidoreductase (5-hydroxylating, lactonizing)

Reaction(IUBMB)

cyclopentanone + NADPH + H+ + O2 = 5-valerolactone + NADP+ + H2O [RN:R02554]

Reaction(KEGG)

R02554

Substrate

cyclopentanone [CPD:C00557];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]

Product

5-valerolactone [CPD:C02240];
NADP+ [CPD:C00006];
H2O [CPD:C00001]

History

EC 1.14.13.16 created 1976

Orthology

K23517

cyclopentanone monooxygenase

Reference

1 [PMID:4349113]

Authors

Griffin M, Trudgill PW.

Title

The metabolism of cyclopentanol by Pseudomonas N.C.I.B. 9872.

Journal

Biochem J 129:595-603 (1972)
DOI:10.1042/bj1290595

Reference

2 [PMID:4313]

Authors

Griffin M, Trudgill PW.

Title

Purification and properties of cyclopentanone oxygenase of Pseudomonas NCIB 9872.

Journal

Eur J Biochem 63:199-209 (1976)
DOI:10.1111/j.1432-1033.1976.tb10222.x

Other DBs

ExplorEnz - The Enzyme Database:

1.14.13.16

IUBMB Enzyme Nomenclature:

1.14.13.16

ExPASy - ENZYME nomenclature database:

1.14.13.16

BRENDA, the Enzyme Database:

1.14.13.16

CAS:	37364-15-1

DBGET integrated database retrieval system