KEGG   ENZYME: 1.14.13.161
Entry
EC 1.14.13.161              Enzyme                                 
Name
(+)-camphor 6-exo-hydroxylase;
(+)-camphor 6-hydroxylase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
Sysname
(+)-camphor,NADPH:oxygen oxidoreductase (6-exo-hydroxylating)
Reaction(IUBMB)
(+)-camphor + NADPH + H+ + O2 = (+)-6-exo-hydroxycamphor + NADP+ + H2O [RN:R10045]
Reaction(KEGG)
R10045
Substrate
(+)-camphor [CPD:C00808];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
(+)-6-exo-hydroxycamphor [CPD:C20322];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Comment
A cytochrome P-450 monooxygenase isolated from Salvia officinalis (sage). Involved in the catabolism of camphor in senescent tissue.
History
EC 1.14.13.161 created 2012
Pathway
ec00907  Pinene, camphor and geraniol degradation
Reference
1  [PMID:1550356]
  Authors
Funk C, Koepp AE, Croteau R
  Title
Catabolism of camphor in tissue cultures and leaf disks of common sage (Salvia officinalis).
  Journal
Arch Biochem Biophys 294:306-13 (1992)
DOI:10.1016/0003-9861(92)90173-T
Reference
2  [PMID:12231778]
  Authors
Funk C, Croteau R
  Title
Induction and Characterization of a Cytochrome P-450-Dependent Camphor Hydroxylase in Tissue Cultures of Common Sage (Salvia officinalis).
  Journal
Plant Physiol 101:1231-1237 (1993)
DOI:10.1104/pp.101.4.1231
Other DBs
ExplorEnz - The Enzyme Database: 1.14.13.161
IUBMB Enzyme Nomenclature: 1.14.13.161
ExPASy - ENZYME nomenclature database: 1.14.13.161
BRENDA, the Enzyme Database: 1.14.13.161

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Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
All databases (11)   

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