KEGG   ENZYME: 1.14.13.243
Entry
EC 1.14.13.243              Enzyme                                 
Name
toluene 2-monooxygenase;
tomA1/2/3/4/5 (gene names);
toluene ortho-monooxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
Sysname
toluene,NADH:oxygen oxidoreductase (2,3-dihydroxylating)
Reaction(IUBMB)
(1) toluene + NADH + H+ + O2 = 2-methylphenol + NAD+ + H2O [RN:R03560];
(2) 2-methylphenol + NADH + H+ + O2 = 3-methylcatechol + NAD+ + H2O [RN:R03608]
Reaction(KEGG)
R03560 R03608
Substrate
toluene [CPD:C01455];
NADH [CPD:C00004];
H+ [CPD:C00080];
O2 [CPD:C00007];
2-methylphenol
Product
2-methylphenol;
NAD+ [CPD:C00003];
H2O [CPD:C00001];
3-methylcatechol [CPD:C02923]
Comment
The enzyme, characterized from the bacterium Burkholderia cepacia, belongs to a class of nonheme, oxygen-dependent diiron enzymes. It contains a hydroxylase component with two binuclear iron centers, an NADH-oxidoreductase component containing FAD and a [2Fe-2S] iron-sulfur cluster, and a third component involved in electron transfer between the hydroxylase and the reductase. The enzyme dihydroxylates its substrate in two sequential hydroxylations, initially forming 2-methylphenol, which is hydroxylated to 3-methylcatechol.
History
EC 1.14.13.243 created 2019
Pathway
ec00623  Toluene degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K16242  phenol/toluene 2-monooxygenase (NADH) P3/A3
K16243  phenol/toluene 2-monooxygenase (NADH) P1/A1
K16244  phenol/toluene 2-monooxygenase (NADH) P2/A2
K16245  phenol/toluene 2-monooxygenase (NADH) P4/A4
K16246  phenol/toluene 2-monooxygenase (NADH) P5/A5
Genes
PSD: DSC_04415 DSC_04420 DSC_04425 DSC_04430 DSC_04435
RTH: LRK53_10140 LRK53_10145 LRK53_10150 LRK53_10155 LRK53_10245
RBD: ALSL_0896 ALSL_0897 ALSL_0898 ALSL_0899 ALSL_0900
PRE: PCA10_06970(dmpL) PCA10_06980(dmpM) PCA10_06990(dmpN) PCA10_07000(dmpO) PCA10_07010(dmpP)
PFUW: KF707C_6700(dmpL) KF707C_6710(dmpM) KF707C_6720(dmpN) KF707C_6730(dmpO) KF707C_6740(dmpP)
PCQ: PcP3B5_25310(mphL) PcP3B5_25320(dmpM) PcP3B5_25330(tmoA) PcP3B5_25340 PcP3B5_25350(dmpP)
PPG: PputGB1_3306 PputGB1_3307 PputGB1_3308 PputGB1_3309 PputGB1_3310
PPJ: RK21_04242 RK21_04243 RK21_04244 RK21_04245 RK21_04246 RK21_04247
PVR: PverR02_14660 PverR02_14665 PverR02_14670 PverR02_14675 PverR02_14680
PKC: PKB_1742(dmpL) PKB_1743 PKB_1744(dmpN) PKB_1745 PKB_1746(dmpP)
PALK: PSAKL28_05880 PSAKL28_05890 PSAKL28_05900 PSAKL28_05910 PSAKL28_05920
PALL: UYA_20180 UYA_20185 UYA_20190 UYA_20195 UYA_20200
PUM: HGP31_14970 HGP31_14975 HGP31_14980 HGP31_14985 HGP31_14990
PLAL: FXN65_03415 FXN65_03420 FXN65_03425 FXN65_03430 FXN65_03435
PPHN: HU825_04995 HU825_05000 HU825_05005 HU825_05010 HU825_05015
PIZ: LAB08_R22490 LAB08_R22500 LAB08_R22510 LAB08_R22520 LAB08_R22530
PKM: PZ739_17290 PZ739_17295 PZ739_17300 PZ739_17305 PZ739_17310
PKK: QQ992_10215 QQ992_10220 QQ992_10225 QQ992_10230 QQ992_10235
PTRL: OU419_14775 OU419_14780 OU419_14785 OU419_14790 OU419_14795
AVN: Avin_08810(dmpP) Avin_08820(dmpO) Avin_08830(dmpN) Avin_08840(dmpM) Avin_08850(dpmL) Avin_30710(lapP) Avin_30720(lapO) Avin_30730(lapN) Avin_30740(lapM) Avin_30750(lapL)
AVL: AvCA_08810(dmpP) AvCA_08820(dmpO) AvCA_08830(dmpN) AvCA_08840(dmpM) AvCA_08850(dpmL) AvCA_30710(lapP) AvCA_30720(lapO) AvCA_30730(lapN) AvCA_30740(lapM) AvCA_30750(lapL)
AVD: AvCA6_08810(dmpP) AvCA6_08820(dmpO) AvCA6_08830(dmpN) AvCA6_08840(dmpM) AvCA6_08850(dpmL) AvCA6_30710(lapP) AvCA6_30720(lapO) AvCA6_30730(lapN) AvCA6_30740(lapM) AvCA6_30750(lapL)
HPEG: EAO82_09380 EAO82_09385 EAO82_09390 EAO82_09395 EAO82_09400
HAES: LO767_17625 LO767_17630 LO767_17635 LO767_17640 LO767_17645
PPHA: BVH74_06110 BVH74_06115 BVH74_06120 BVH74_06125 BVH74_06130
MAD: HP15_4025 HP15_4026 HP15_4027 HP15_4028 HP15_4029
MSR: AU15_09285 AU15_09290 AU15_09305 AU15_20690 AU15_20695 AU15_20705 AU15_20710
MLQ: ASQ50_09240 ASQ50_09245 ASQ50_09250 ASQ50_09255 ASQ50_09260
MSQ: BKP64_13875 BKP64_13880 BKP64_13885 BKP64_13890 BKP64_13895
MARJ: MARI_05340(mphL) MARI_05350(dmpM) MARI_05360(tmoA) MARI_05370 MARI_05380(dmpP)
MALL: PBN92_01625 PBN92_01630 PBN92_01635 PBN92_01640 PBN92_01645
MSHE: MAALD49_03340(mphL) MAALD49_03350(mphM) MAALD49_03360(mphN) MAALD49_03370(mphO) MAALD49_03380(mphP) MAALD49_03770(mphL) MAALD49_03780(mphM) MAALD49_03790(mphN) MAALD49_03800(mphO) MAALD49_03810(mphP)
MANP: EHN06_02400 EHN06_02405 EHN06_02410 EHN06_02415 EHN06_02420
PSPG: AK823_07300 AK823_07305 AK823_07310 AK823_07315 AK823_07320
PSYG: AK825_07395 AK825_07400 AK825_07405 AK825_07410 AK825_07415
ABK: LX00_05865 LX00_05870 LX00_05875 LX00_05880 LX00_05885
ABAU: IX87_04540 IX87_04545 IX87_04550 IX87_04555 IX87_04560
ACC: BDGL_000470(mphP) BDGL_000471(mphO) BDGL_000472(mphN) BDGL_000473(mphM) BDGL_000474(mphL)
ALC: OTEC02_12945 OTEC02_12950 OTEC02_12955 OTEC02_12960 OTEC02_12965
ASEI: I8T81_12960 I8T81_12965 I8T81_12970 I8T81_12975 I8T81_12980
ACD: AOLE_13300 AOLE_13305 AOLE_13310 AOLE_13315 AOLE_13320
AJO: RZ95_18640 RZ95_18645 RZ95_18650 RZ95_18655 RZ95_18660
ACW: A0J50_11600 A0J50_11605 A0J50_11610 A0J50_11615 A0J50_11620
ALA: BFG52_11000 BFG52_11005 BFG52_11010 BFG52_11015 BFG52_11020
ADV: DJ533_01815 DJ533_01820 DJ533_01825 DJ533_01830 DJ533_01835 DJ533_10995 DJ533_11000 DJ533_11005 DJ533_11010 DJ533_11015
AWU: BEN71_12685 BEN71_12690 BEN71_12695 BEN71_12700 BEN71_12705
AGU: AS4_16410(dsoF) AS4_16420(dsoE) AS4_16430(dsoD) AS4_16440(dsoC) AS4_16450(dsoB)
ABER: BSR55_16090 BSR55_16095 BSR55_16100 BSR55_16105 BSR55_16110
ACHI: CDG60_14300 CDG60_14305 CDG60_14310 CDG60_14315 CDG60_14320
ATG: J4G44_06365 J4G44_06370 J4G44_06375 J4G44_06380 J4G44_06385
ACIU: A3K93_13810
ACIE: KIP84_12125 KIP84_12130 KIP84_12135 KIP84_12140 KIP84_12145
AFUS: EYZ66_02625 EYZ66_02630 EYZ66_02635 EYZ66_02640 EYZ66_02645
CZA: CYCME_2107 CYCME_2108 CYCME_2109 CYCME_2110 CYCME_2111
BLEP: AL038_01325 AL038_01330 AL038_01335
THIS: HZT40_13275 HZT40_13280 HZT40_13285 HZT40_13290 HZT40_13300
TBN: TBH_C0906 TBH_C0907 TBH_C0908 TBH_C0909 TBH_C0910
MARS: A8C75_10395 A8C75_10400 A8C75_10405 A8C75_10410 A8C75_10415
MGEO: CFI10_13960 CFI10_13965 CFI10_13970 CFI10_13975 CFI10_13980
MSEC: LN244_11600 LN244_11605 LN244_11610 LN244_11615 LN244_11620
MRZ: KDW95_03635 KDW95_03640 KDW95_03645 KDW95_03650 KDW95_03655
NCU: F0U83_03005 F0U83_03010 F0U83_03015 F0U83_03020 F0U83_03025
NJP: NEJAP_0663(dmpL) NEJAP_0664(dmpM) NEJAP_0665(dmpN) NEJAP_0666(dmpO) NEJAP_0667(dmpP)
NIK: F5I99_10130 F5I99_10135 F5I99_10140 F5I99_10145 F5I99_10150
AJP: AMJAP_3006(dmpP) AMJAP_3007(dmpO) AMJAP_3008(dmpN) AMJAP_3009(dmpM) AMJAP_3010(dmpL)
SINI: GT972_13680 GT972_13685 GT972_13690 GT972_13695 GT972_13700
NZO: SAMEA4504057_0438(mphL) SAMEA4504057_0439(dmpM) SAMEA4504057_0440(tmoA) SAMEA4504057_0441 SAMEA4504057_0442(mphP)
NCI: NCTC10296_00919(mphP) NCTC10296_00920 NCTC10296_00921(tmoA) NCTC10296_00922(dmpM) NCTC10296_00923(mphL)
NWD: H3L96_04785 H3L96_04790 H3L96_04795 H3L96_04800 H3L96_04805
NDU: LVJ88_00550 LVJ88_00555 LVJ88_00560 LVJ88_00565 LVJ88_00570
VFF: VITFI_CDS1382 VITFI_CDS1383 VITFI_CDS1384 VITFI_CDS1385 VITFI_CDS1386
PTES: JQU52_04820 JQU52_04825 JQU52_04830 JQU52_04835 JQU52_04840
USU: LVJ78_03620 LVJ78_03625 LVJ78_03630 LVJ78_03635 LVJ78_03640
AQL: BXU06_12755 BXU06_12760 BXU06_12765 BXU06_12770 BXU06_12775 BXU06_16820 BXU06_16825 BXU06_16830 BXU06_16835 BXU06_16840
RPI: Rpic_4626 Rpic_4627 Rpic_4628 Rpic_4629 Rpic_4630
RPF: Rpic12D_3550 Rpic12D_3551 Rpic12D_3552 Rpic12D_3553 Rpic12D_3554
RPJ: N234_08110 N234_08115 N234_08120 N234_08125 N234_08130
REH: H16_B0540(poxB) H16_B0541(poxC) H16_B0542(poxD) H16_B0543(poxE) H16_B0544(poxF)
CNC: CNE_2c04860(poxB) CNE_2c04870(poxC) CNE_2c04880(poxD) CNE_2c04890(poxE) CNE_2c04900(poxF)
REU: Reut_A1700 Reut_A1701 Reut_A1702 Reut_A1703 Reut_A1704 Reut_B5681 Reut_B5682 Reut_B5683 Reut_B5684 Reut_B5685
RME: Rmet_1326(tomA5) Rmet_1327(tomA4) Rmet_1328(tomA3) Rmet_1329(tomA2) Rmet_1330(tomA1) Rmet_1782(phyE) Rmet_1783(phyD) Rmet_1784(phyC) Rmet_1785(phyB) Rmet_1786(phyA)
CBW: RR42_s2488 RR42_s2489 RR42_s2490 RR42_s2491 RR42_s2492
CCUP: BKK81_27050 BKK81_27055 BKK81_27060 BKK81_27065 BKK81_27070
CUP: BKK80_29250 BKK80_29255 BKK80_29260 BKK80_29265 BKK80_29270
CUU: BKK79_35200 BKK79_35205 BKK79_35210 BKK79_35215 BKK79_35220
COX: E0W60_07735 E0W60_07740 E0W60_07745 E0W60_07750 E0W60_07755
CCAX: KZ686_09945 KZ686_09950 KZ686_09955 KZ686_09960 KZ686_09965
CUK: KB879_20150 KB879_20155 KB879_20160 KB879_20165 KB879_20170
CNAN: A2G96_22730 A2G96_22735 A2G96_22740 A2G96_22745 A2G96_22750
BVI: Bcep1808_7594 Bcep1808_7595 Bcep1808_7596 Bcep1808_7597 Bcep1808_7598
BUR: Bcep18194_B2966 Bcep18194_B2967 Bcep18194_B2968 Bcep18194_B2969 Bcep18194_B2970
BCEN: DM39_4839(dmpP) DM39_4840(phO) DM39_4841(phN) DM39_4842(dmpM) DM39_4843(mphL)
BCT: GEM_5408 GEM_5409 GEM_5410 GEM_5411 GEM_5412
BCED: DM42_4998(dmpP) DM42_4999(phO) DM42_5000(phN) DM42_5001(dmpM) DM42_5002(phL)
BCON: NL30_24625 NL30_24630 NL30_24635 NL30_24640 NL30_24645
BDF: WI26_15940 WI26_15945 WI26_15950 WI26_15955 WI26_15960
BTEI: WS51_00515 WS51_00520 WS51_00525 WS51_00530 WS51_00535
BPSL: WS57_12190 WS57_12195 WS57_12200 WS57_12205 WS57_12210
BSTL: BBJ41_10465 BBJ41_10470 BBJ41_10475 BBJ41_10480 BBJ41_10485
BANN: JFN94_19080 JFN94_19085 JFN94_19090 JFN94_19095 JFN94_19100
BAEN: L3V59_30350 L3V59_30355 L3V59_30360 L3V59_30365 L3V59_30370
BYI: BYI23_C000520 BYI23_C000530 BYI23_C000540 BYI23_C000550(mmoB_dmpM) BYI23_C000560
BUE: BRPE67_CCDS12510 BRPE67_CCDS12520(mmoB_dmpM) BRPE67_CCDS12530 BRPE67_CCDS12540 BRPE67_CCDS12550
BUZ: AYM40_16195 AYM40_16200 AYM40_16205 AYM40_16210 AYM40_16215
PARB: CJU94_38070 CJU94_38075 CJU94_38080 CJU94_38085 CJU94_38090
PTER: C2L65_07810 C2L65_07815 C2L65_07820 C2L65_07825 C2L65_07830
PPAI: E1956_29220 E1956_29225 E1956_29230 E1956_29235 E1956_29240
PPK: U875_01925 U875_01930 U875_01935 U875_01940 U875_01945
PRB: X636_07525 X636_07530 X636_07535 X636_07540 X636_07545
CABK: NK8_49940 NK8_49950 NK8_49960 NK8_49970 NK8_49980
LIMN: HKT17_03880 HKT17_03885 HKT17_03890 HKT17_03895 HKT17_03900
BOJ: CBF45_04540 CBF45_04545 CBF45_04550 CBF45_04555 CBF45_04560
APES: FOC84_00355 FOC84_00360 FOC84_00365 FOC84_00370 FOC84_00375
CDN: BN940_04341 BN940_04346 BN940_04351 BN940_04356 BN940_04361
AFA: UZ73_17835 UZ73_17840 UZ73_17845 UZ73_17850 UZ73_17855
AFQ: AFA_08520 AFA_08525 AFA_08530 AFA_08535 AFA_08540
AAQU: D3M96_09740 D3M96_09745 D3M96_09750 D3M96_09755 D3M96_09760
AAMM: FE795_07735 FE795_07740 FE795_07745 FE795_07750 FE795_07755
PIG: EGT29_26535 EGT29_26540 EGT29_26545 EGT29_26550 EGT29_26555
KGY: EHF36_04925 EHF36_04930 EHF36_04935 EHF36_04940 EHF36_04945
AJS: Ajs_0207 Ajs_0208 Ajs_0209 Ajs_0210 Ajs_0211
ACID: CBP33_01035 CBP33_01055 CBP33_01060
ACIP: CBP36_01140 CBP36_01145 CBP36_01150 CBP36_01155 CBP36_01160
ACIN: CBP34_01050 CBP34_01055 CBP34_01060 CBP34_01065 CBP34_01070
ACIS: CBP35_17790 CBP35_17795 CBP35_17800 CBP35_17805 CBP35_17810
AMON: H9L24_14235 H9L24_14240 H9L24_14245 H9L24_14250 H9L24_14255
VEI: Veis_2791 Veis_2792 Veis_2793 Veis_2794 Veis_2795
VBO: CKY39_28530 CKY39_28540 CKY39_28545 CKY39_28550
CTT: CtCNB1_3157 CtCNB1_3158 CtCNB1_3159 CtCNB1_3160 CtCNB1_3161
COF: FOZ74_08255 FOZ74_08260 FOZ74_08265 FOZ74_08270 FOZ74_08275
ADN: Alide_0324 Alide_0325 Alide_0326 Alide_0327 Alide_0328
ADK: Alide2_0271 Alide2_0272 Alide2_0273 Alide2_0274 Alide2_0275
OTD: J1M35_00080 J1M35_00085 J1M35_00090 J1M35_00095 J1M35_00100
HYL: LPB072_18130 LPB072_18135 LPB072_18140 LPB072_18145 LPB072_18150
HPSE: HPF_01905(dmpP) HPF_01910(tbuD) HPF_01915(tmoA2) HPF_01920(dmpM) HPF_01925(mphL)
HYN: F9K07_02700 F9K07_02705 F9K07_02710 F9K07_02715 F9K07_02720
HTN: KI616_01995 KI616_02000 KI616_02005 KI616_02010 KI616_02015
DIH: G7047_01705 G7047_01710 G7047_01715 G7047_01720 G7047_01725
DRG: H9K76_11590 H9K76_11595 H9K76_11600 H9K76_11605 H9K76_11610
SIMP: C6571_13570 C6571_13575 C6571_13580 C6571_13585 C6571_13590
MELA: C6568_07885 C6568_07890 C6568_07895 C6568_07900 C6568_07905
MJE: LVC68_00955 LVC68_00960 LVC68_00965 LVC68_00970 LVC68_00975
STHM: IS481_10480 IS481_10485 IS481_10490 IS481_10495 IS481_10500
SAQA: OMP39_09060 OMP39_09065 OMP39_09070 OMP39_09075 OMP39_09080
MPT: Mpe_A2280(dmpP) Mpe_A2281(dmpO) Mpe_A2282(dmpN) Mpe_A2283(dmpM) Mpe_A2284(dmpL) Mpe_A3305(dmpO) Mpe_A3306(dmpN) Mpe_A3307(dmpM) Mpe_A3308(dmpL)
METP: C1M51_06255 C1M51_06260 C1M51_06265 C1M51_06275 C1M51_06280 C1M51_06285 C1M51_06290 C1M51_06295 C1M51_15440 C1M51_15445 C1M51_15450 C1M51_15455
SNN: EWH46_19245 EWH46_19250 EWH46_19255 EWH46_19260 EWH46_19265
IDC: LRM40_19515 LRM40_19520 LRM40_19525 LRM40_19530 LRM40_19535
LCH: Lcho_3358 Lcho_3359 Lcho_3360 Lcho_3361 Lcho_3362
MASW: AM586_18610 AM586_18615 AM586_18620 AM586_18625 AM586_18630
MLIR: LPB04_16095 LPB04_16100 LPB04_16105 LPB04_16110 LPB04_16115
TMJ: P0M04_30685 P0M04_30690 P0M04_30695 P0M04_30700 P0M04_30705
RBU: PG1C_06885 PG1C_06890 PG1C_06895 PG1C_06900 PG1C_06905
DAR: Daro_3792 Daro_3793 Daro_3794 Daro_3795 Daro_3796
DEY: HYN24_14140 HYN24_14145 HYN24_14150 HYN24_14155 HYN24_14250 HYN24_14255 HYN24_14260 HYN24_14265 HYN24_14270
DDEN: KI615_16920 KI615_16925 KI615_16930 KI615_16935 KI615_16940
DECH: GBK02_02780 GBK02_02785 GBK02_02790 GBK02_02795 GBK02_02800
QAU: KI612_13860 KI612_13865 KI612_13870 KI612_13875 KI612_13880
FLE: KI610_15390 KI610_15395 KI610_15400 KI610_15405 KI610_15500 KI610_15505 KI610_15510 KI610_15515 KI610_15520
AZO: azo1846(lapL) azo1847(lapM) azo1848(lapN) azo1849(lapO) azo1850(lapP) azo2439(poxF) azo2440(poxE) azo2441(poxD) azo2442(poxC) azo2443(poxB)
AOA: dqs_1996 dqs_1997 dqs_1998 dqs_1999 dqs_2000 dqs_2583 dqs_2584 dqs_2585 dqs_2586 dqs_2587
AZD: CDA09_10255 CDA09_10260 CDA09_10265 CDA09_10270 CDA09_10275 CDA09_10410 CDA09_10415 CDA09_10420 CDA09_10425 CDA09_10430
AZR: CJ010_12195 CJ010_12200 CJ010_12205 CJ010_12210 CJ010_12215 CJ010_15245 CJ010_15250 CJ010_15255 CJ010_15260 CJ010_15265
TMZ: Tmz1t_3111 Tmz1t_3112 Tmz1t_3113 Tmz1t_3114 Tmz1t_3115
THU: AC731_001765 AC731_001770 AC731_001775 AC731_001780 AC731_001785
THAU: C4PIVTH_2793(dmpL) C4PIVTH_2794(dmpM) C4PIVTH_2795(dmpN) C4PIVTH_2796(dmpO) C4PIVTH_2797(dmpP)
THK: CCZ27_04535 CCZ27_04540 CCZ27_04545 CCZ27_04555 CCZ27_10665 CCZ27_10670 CCZ27_10675 CCZ27_10680 CCZ27_10685 CCZ27_10780 CCZ27_10785 CCZ27_10790 CCZ27_10795 CCZ27_10800
AZQ: G3580_00470 G3580_00475 G3580_00480 G3580_00485 G3580_00490 G3580_01295 G3580_01300 G3580_01305 G3580_01310 G3580_08210 G3580_08215 G3580_08220 G3580_08225 G3580_08230
STEG: QA637_22950
MTUN: MTUNDRAET4_3881(dmpL) MTUNDRAET4_3882(dmpM) MTUNDRAET4_3883 MTUNDRAET4_3885 MTUNDRAET4_3886(dmpP)
MAAD: AZF01_11200 AZF01_11205 AZF01_11210 AZF01_11215 AZF01_11220
MLUT: JET14_11645 JET14_11650 JET14_11655 JET14_11660 JET14_11665
BVY: NCTC9239_03024(mphL) NCTC9239_03025(dmpM) NCTC9239_03026(tmoA)
SMY: BJP26_18670 BJP26_18675 BJP26_18680 BJP26_18685 BJP26_18690
SHAN: PPZ50_08275 PPZ50_08280 PPZ50_08285 PPZ50_08290 PPZ50_08295
SJP: SJA_C1-11990(tomA1) SJA_C1-12000(tomA2) SJA_C1-12010(tomA3) SJA_C1-12020(tomA4) SJA_C1-12030(tomA5)
SINB: SIDU_08250 SIDU_08255 SIDU_08260 SIDU_08265 SIDU_08270
SYB: TZ53_09070 TZ53_09075 TZ53_09080 TZ53_09085 TZ53_09090
SUFL: FIL70_18925 FIL70_18930 FIL70_18935 FIL70_18940 FIL70_18945
SBAR: H5V43_20575 H5V43_20580 H5V43_20585 H5V43_20590 H5V43_20595
ACIB: ACBT_0275(dmpP) ACBT_0276(dmpO) ACBT_0277(dmpN) ACBT_0278(dmpM) ACBT_0279(dmpL)
AFC: AFAEC_1853(dmpP) AFAEC_1854(dmpO) AFAEC_1855(dmpN) AFAEC_1856(dmpM) AFAEC_1857(dmpL)
AAQI: AAQM_0970(dmpL) AAQM_0971(dmpM) AAQM_0972(dmpN) AAQM_0973(dmpO) AAQM_0974(dmpP)
ACLO: ACLO_a0150(dmpP) ACLO_a0151(dmpO) ACLO_a0152(dmpN) ACLO_a0153(dmpM) ACLO_a0154(dmpL)
ADZ: ADFLV_2564(dmpP) ADFLV_2565(dmpO) ADFLV_2566(dmpN) ADFLV_2567(dmpM) ADFLV_2568(dmpL)
ARC: ABLL_2455 ABLL_2456 ABLL_2457 ABLL_2458 ABLL_2459
AROS: NJU99_01595 NJU99_01600 NJU99_01605 NJU99_01610 NJU99_01615
ALK: ALEK_0371(dmpL) ALEK_0372(dmpM) ALEK_0373(dmpN) ALEK_0374(dmpO) ALEK_0375(dmpP)
AANA: AANAER_1246(dmpL) AANAER_1247(dmpM) AANAER_1248(dmpN) AANAER_1249(dmpO) AANAER_1250(dmpP)
BACI: B1NLA3E_08455 B1NLA3E_08460 B1NLA3E_08465
ASOC: CB4_02441(mphL) CB4_02442(dmpM) CB4_02443(tmoA)
BTS: Btus_0959 Btus_0960 Btus_0961
KYR: CVV65_10610 CVV65_10615 CVV65_10620 CVV65_11330 CVV65_11335 CVV65_11340
SAY: TPY_0628 TPY_0629 TPY_0630 TPY_0631 TPY_0634(benC)
SAP: Sulac_3005 Sulac_3008 Sulac_3009 Sulac_3010 Sulac_3011
MSA: Mycsm_01964 Mycsm_01965 Mycsm_01966 Mycsm_01967 Mycsm_01968
MLL: B1R94_25100 B1R94_25110 B1R94_25115
MMAG: MMAD_31790 MMAD_31810(mphN)
MCRO: MI149_22720 MI149_22730
MHIB: MHIB_39890(mphP)
CCYC: SCMU_04650(mphP)
ROZ: CBI38_31750 CBI38_32160 CBI38_32255
GOQ: ACH46_03525 ACH46_03530 ACH46_03535 ACH46_03540 ACH46_03545
GOC: CXX93_06730 CXX93_06735 CXX93_06740 CXX93_06745 CXX93_06750
GAM: GII34_22040 GII34_22045 GII34_22050 GII34_22055 GII34_22060
GSI: P5P27_15490 P5P27_15495 P5P27_15500 P5P27_15505 P5P27_15510
TOY: FO059_13965 FO059_13970 FO059_13975 FO059_13980 FO059_13985
JTE: ASJ30_00060 ASJ30_00065 ASJ30_00070 ASJ30_00075 ASJ30_00080
JLI: EXU32_15385 EXU32_15390 EXU32_15395 EXU32_15400 EXU32_15405
JME: EEW87_015365 EEW87_015370 EEW87_015375 EEW87_015380 EEW87_015385
JAY: H7A72_00060 H7A72_00065 H7A72_00070 H7A72_00080
JCR: O9K63_12545 O9K63_12550 O9K63_12555 O9K63_12560 O9K63_12565
PHW: G7075_13205 G7075_13210 G7075_13215 G7075_13225
AUS: IPK37_11610 IPK37_11620 IPK37_11625 IPK37_11640
RAIN: Rai3103_07175 Rai3103_07185 Rai3103_07190 Rai3103_07195
NMES: H9L09_04340
TCU: Tcur_0524 Tcur_0525 Tcur_0526 Tcur_0527 Tcur_0530
AACD: LWP59_26105 LWP59_26110 LWP59_26115 LWP59_26120 LWP59_26125 LWP59_38095 LWP59_38100 LWP59_38105 LWP59_38110 LWP59_38115
ARHD: VSH64_31590 VSH64_31595 VSH64_31600 VSH64_31605 VSH64_31610
PDX: Psed_0766 Psed_0767 Psed_0768 Psed_0769 Psed_0770
PSUU: Psuf_068230(mphL) Psuf_068240 Psuf_068250(mphN) Psuf_068280(mphP)
COY: HF329_27145
CFIL: MYF79_02125
CHOR: MKQ68_23840
NKF: Nkreftii_004063
 » show all
Reference
1  [PMID:7578004]
  Authors
Newman LM, Wackett LP
  Title
Purification and characterization of toluene 2-monooxygenase from Burkholderia cepacia G4.
  Journal
Biochemistry 34:14066-76 (1995)
DOI:10.1021/bi00043a012
Reference
2  [PMID:9925593]
  Authors
Yeager CM, Bottomley PJ, Arp DJ, Hyman MR
  Title
Inactivation of toluene 2-monooxygenase in Burkholderia cepacia G4 by alkynes.
  Journal
Appl Environ Microbiol 65:632-9 (1999)
DOI:10.1128/AEM.65.2.632-639.1999
Reference
3  [PMID:11751810]
  Authors
Canada KA, Iwashita S, Shim H, Wood TK
  Title
Directed evolution of toluene ortho-monooxygenase for enhanced 1-naphthol synthesis and chlorinated ethene degradation.
  Journal
J Bacteriol 184:344-9 (2002)
DOI:10.1128/jb.184.2.344-349.2002
Other DBs
ExplorEnz - The Enzyme Database: 1.14.13.243
IUBMB Enzyme Nomenclature: 1.14.13.243
ExPASy - ENZYME nomenclature database: 1.14.13.243
BRENDA, the Enzyme Database: 1.14.13.243

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Pathway (7)   
   KEGG PATHWAY (6)   
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Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
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   KEGG RCLASS (1)   
Gene (3292)   
   KEGG ORTHOLOGY (5)   
   KEGG GENES (1172)   
   KEGG MGENES (1752)   
   RefGene (363)   
All databases (3310)   

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