KEGG   ENZYME: 1.14.13.31
Entry
EC 1.14.13.31               Enzyme                                 
Name
2-nitrophenol 2-monooxygenase;
2-nitrophenol oxygenase;
nitrophenol oxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
Sysname
2-nitrophenol,NADPH:oxygen 2-oxidoreductase (2-hydroxylating, nitrite-forming)
Reaction(IUBMB)
2-nitrophenol + 2 NADPH + 2 H+ + O2 = catechol + nitrite + 2 NADP+ + H2O [RN:R00828]
Reaction(KEGG)
R00828
Substrate
2-nitrophenol [CPD:C01988];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
catechol [CPD:C00090];
nitrite [CPD:C00088];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Comment
Involved in the metabolism of nitro-aromatic compounds by a strain of Pseudomonas putida.
History
EC 1.14.13.31 created 1989
Reference
1  [PMID:3752997]
  Authors
Zeyer J, Kocher HP, Timmis KN.
  Title
Influence of para-substituents on the oxidative metabolism of o-nitrophenols by Pseudomonas putida B2.
  Journal
Appl Environ Microbiol 52:334-9 (1986)
DOI:10.1128/AEM.52.2.334-339.1986
Other DBs
ExplorEnz - The Enzyme Database: 1.14.13.31
IUBMB Enzyme Nomenclature: 1.14.13.31
ExPASy - ENZYME nomenclature database: 1.14.13.31
UM-BBD (Biocatalysis/Biodegradation Database): 1.14.13.31
BRENDA, the Enzyme Database: 1.14.13.31
CAS: 104520-84-5

  All links  
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Protein sequence (1)   
   UniProt (1)   
DNA sequence (3)   
   GenBank (2)   
   EMBL (1)   
Enzyme (1)   
   UMBBD-EC (1)   
All databases (15)   

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