KEGG   ENZYME: 1.14.13.44
Entry
EC 1.14.13.44               Enzyme                                 
Name
2-hydroxybiphenyl 3-monooxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
Sysname
2-hydroxybiphenyl,NADH:oxygen oxidoreductase (3-hydroxylating)
Reaction(IUBMB)
2-hydroxybiphenyl + NADH + H+ + O2 = 2,3-dihydroxybiphenyl + NAD+ + H2O [RN:R03964]
Reaction(KEGG)
R03964
Substrate
2-hydroxybiphenyl [CPD:C02499];
NADH [CPD:C00004];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
2,3-dihydroxybiphenyl [CPD:C02526];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Comment
Also converts 2,2'-dihydroxybiphenyl into 2,2',3-trihydroxy-biphenyl.
History
EC 1.14.13.44 created 1992
Reference
1  [PMID:3214154]
  Authors
Kohler HP, Kohler-Staub D, Focht DD.
  Title
Degradation of 2-hydroxybiphenyl and 2,2'-dihydroxybiphenyl by Pseudomonas sp. strain HBP1.
  Journal
Appl Environ Microbiol 54:2683-8 (1988)
DOI:10.1128/AEM.54.11.2683-2688.1988
Other DBs
ExplorEnz - The Enzyme Database: 1.14.13.44
IUBMB Enzyme Nomenclature: 1.14.13.44
ExPASy - ENZYME nomenclature database: 1.14.13.44
UM-BBD (Biocatalysis/Biodegradation Database): 1.14.13.44
BRENDA, the Enzyme Database: 1.14.13.44
CAS: 118251-39-1

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Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Protein sequence (15)   
   UniProt (2)   
   PDBSTR (12)   
   PMD (1)   
3D Structure (4)   
   PDB (4)   
Enzyme (1)   
   UMBBD-EC (1)   
All databases (29)   

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