KEGG   ENZYME: 1.14.13.58
Entry
EC 1.14.13.58               Enzyme                                 
Name
benzoyl-CoA 3-monooxygenase;
benzoyl-CoA 3-hydroxylase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
Sysname
benzoyl-CoA,NADPH:oxygen oxidoreductase (3-hydroxylating)
Reaction(IUBMB)
benzoyl-CoA + NADPH + H+ + O2 = 3-hydroxybenzoyl-CoA + NADP+ + H2O [RN:R02449]
Reaction(KEGG)
R02449
Substrate
benzoyl-CoA [CPD:C00512];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
3-hydroxybenzoyl-CoA [CPD:C05195];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Comment
The enzyme from the denitrifying bacterium Pseudomonas KB740 catalyses a flavin-requiring reaction (FAD or FMN). Benzoate is not a substrate.
History
EC 1.14.13.58 created 1999
Reference
1  [PMID:7851381]
  Authors
Niemetz R, Altenschmidt U, Brucker S, Fuchs G.
  Title
Benzoyl-coenzyme-A 3-monooxygenase, a flavin-dependent hydroxylase. Purification, some properties and its role in aerobic benzoate oxidation via gentisate in a denitrifying bacterium.
  Journal
Eur J Biochem 227:161-8 (1995)
DOI:10.1111/j.1432-1033.1995.tb20372.x
Other DBs
ExplorEnz - The Enzyme Database: 1.14.13.58
IUBMB Enzyme Nomenclature: 1.14.13.58
ExPASy - ENZYME nomenclature database: 1.14.13.58
BRENDA, the Enzyme Database: 1.14.13.58
CAS: 151616-61-4

  All links  
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Protein sequence (1)   
   UniProt (1)   
DNA sequence (12)   
   GenBank (6)   
   EMBL (6)   
All databases (22)   

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