KEGG ENZYME: 1.14.14.122

ENZYME: 1.14.14.122

Entry

EC 1.14.14.122              Enzyme

Name

oryzalexin E synthase;
CYP76M6

Class

Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

Sysname

ent-sandaracopimaradien-3beta-ol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (oryzalexin-E-forming)

Reaction(IUBMB)

ent-sandaracopimaradien-3beta-ol + [reduced NADPH---hemoprotein reductase] + O2 = oryzalexin E + [oxidized NADPH---hemoprotein reductase] + H2O [RN:R11657]

Reaction(KEGG)

R11657

Substrate

ent-sandaracopimaradien-3beta-ol [CPD:C21560];
[reduced NADPH---hemoprotein reductase] [CPD:C03024];
O2 [CPD:C00007]

Product

oryzalexin E [CPD:C21561];
[oxidized NADPH---hemoprotein reductase] [CPD:C03161];
H2O [CPD:C00001]

Comment

A cytochrome P-450 (heme-thiolate) protein. Isolated from Oryza sativa (rice). Oryzalexin E is a phytoalexin.

History

EC 1.14.14.122 created 2014 as EC 1.14.13.192, transferred 2018 to EC 1.14.14.122

Pathway

ec00904