Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy

(+)-marmesin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase

(+)-marmesin + [reduced NADPH---hemoprotein reductase] + O2 = psoralen + [oxidized NADPH---hemoprotein reductase] + acetone + 2 H2O [RN:R08207]

R08207
Reaction

(+)-marmesin [CPD:C09276];
[reduced NADPH---hemoprotein reductase] [CPD:C03024];
O2 [CPD:C00007]

This microsomal cytochrome P-450 (heme-thiolate) enzyme is rather specific for (+)-marmesin, although it can also accept 5-hydroxymarmesin to a much lesser extent. Furanocoumarins protect plants from fungal invasion and herbivore attack. (+)-Columbianetin, the angular furanocoumarin analogue of the linear furanocoumarin (+)-marmesin, acts as a competitive inhibitor even though it is not a substrate.

EC 1.14.14.141 created 2007 as EC 1.14.13.102, transferred 2018 to EC 1.14.14.141

1  [PMID:17068340]