KEGG   ENZYME: 1.14.14.72
Entry
EC 1.14.14.72               Enzyme                                 
Name
drimenol monooxygenase;
PhDOX1
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
Sysname
drimenol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (drimendiol-forming)
Reaction(IUBMB)
drimenol + [reduced NADPH---hemoprotein reductase] + O2 = drimendiol + [oxidized NADPH---hemoprotein reductase] + H2O [RN:R12010]
Reaction(KEGG)
R12010
Substrate
drimenol [CPD:C19743];
[reduced NADPH---hemoprotein reductase] [CPD:C03024];
O2 [CPD:C00007]
Product
drimendiol [CPD:C21843];
[oxidized NADPH---hemoprotein reductase] [CPD:C03161];
H2O [CPD:C00001]
Comment
A cytochrome P-450 (heme-thiolate) protein isolated from the plant Persicaria hydropiper (water pepper).
History
EC 1.14.14.72 created 2018
Orthology
K22691  drimenol monooxygenase
Reference
1  [PMID:28258968]
  Authors
Henquet MGL, Prota N, van der Hooft JJJ, Varbanova-Herde M, Hulzink RJM, de Vos M, Prins M, de Both MTJ, Franssen MCR, Bouwmeester H, Jongsma M
  Title
Identification of a drimenol synthase and drimenol oxidase from Persicaria hydropiper, involved in the biosynthesis of insect deterrent drimanes.
  Journal
Plant J 90:1052-1063 (2017)
DOI:10.1111/tpj.13527
  Sequence
[ag:AHF22835]
Other DBs
ExplorEnz - The Enzyme Database: 1.14.14.72
IUBMB Enzyme Nomenclature: 1.14.14.72
ExPASy - ENZYME nomenclature database: 1.14.14.72
BRENDA, the Enzyme Database: 1.14.14.72

  All links  
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (4)   
   InterPro (4)   
All databases (16)   

Download RDF
DBGET integrated database retrieval system