KEGG ENZYME: 1.14.15.1

ENZYME: 1.14.15.1

Entry

EC 1.14.15.1                Enzyme

Name

camphor 5-monooxygenase;
camphor 5-exo-methylene hydroxylase;
2-bornanone 5-exo-hydroxylase;
bornanone 5-exo-hydroxylase;
camphor 5-exo-hydroxylase;
camphor 5-exohydroxylase;
camphor hydroxylase;
d-camphor monooxygenase;
methylene hydroxylase;
methylene monooxygenase;
D-camphor-exo-hydroxylase;
camphor methylene hydroxylase

Class

Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor

Sysname

(+)-camphor,reduced putidaredoxin:oxygen oxidoreductase (5-hydroxylating)

Reaction(IUBMB)

(+)-camphor + reduced putidaredoxin + O2 = (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O [RN:R03818]

Reaction(KEGG)

R03818;
(other) R13092

Substrate

(+)-camphor [CPD:C00808];
reduced putidaredoxin [CPD:C02069];
O2 [CPD:C00007]

Product

(+)-exo-5-hydroxycamphor [CPD:C03448];
oxidized putidaredoxin [CPD:C03302];
H2O [CPD:C00001]

Comment

A heme-thiolate protein (P-450). Also acts on (-)-camphor and 1,2-campholide, forming 5-exo-hydroxy-1,2-campholide.