KEGG   ENZYME: 1.14.19.27
Entry
EC 1.14.19.27               Enzyme                                 
Name
sn-2 palmitoyl-lipid 9-desaturase;
DesC2
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
Sysname
1-acyl-2-palmitoyl-[glycerolipid],ferredoxin:oxygen oxidoreductase (9,10 cis-dehydrogenating)
Reaction(IUBMB)
a 1-acyl-2-palmitoyl-[glycerolipid] + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+ = a 1-acyl-2-palmitoleoyl-[glycerolipid] + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O
Substrate
1-acyl-2-palmitoyl-[glycerolipid];
reduced ferredoxin [iron-sulfur] cluster [CPD:C00138];
O2 [CPD:C00007];
H+ [CPD:C00080]
Product
1-acyl-2-palmitoleoyl-[glycerolipid];
oxidized ferredoxin [iron-sulfur] cluster [CPD:C00139];
H2O [CPD:C00001]
Comment
The enzyme, characterized from the cyanobacterium Nostoc sp. 36, introduces a cis double bond at carbon 9 of palmitoyl groups (16:0) attached to the sn-2 position of glycerolipids.
History
EC 1.14.19.27 created 2015
Orthology
K23036  sn-2 palmitoyl-lipid 9-desaturase
Genes
RSB: RS694_11940
JSV: CNX70_12100
JAS: FJQ89_00725
JLV: G3257_12175
MESO: BSQ44_12620
NIY: FQ775_20460
RHZ: RHPLAN_00620
SPHL: LPB140_03920
CYA: CYA_2349
CYB: CYB_0861
SYNP: Syn7502_02944
CMP: Cha6605_5479
CYN: Cyan7425_4595 Cyan7425_4777
CEP: Cri9333_3550
TVN: NIES2134_116370(desC3)
SLW: BRW62_05980
AMR: AM1_0821
ACAM: HRE53_02700
TEL: tll1719(desC3)
THN: NK55_05235(desF)
THEC: FFX45_07095
LEN: LEP3755_56650
LET: O77CONTIG1_03244
LBO: LBWT_10530 LBWT_44670
KOV: K9N68_22245 K9N68_36270
LSC: KIK02_06945 KIK02_10470
LSK: J5X98_08390
HHG: XM38_018600
PSEU: Pse7367_2216
PSER: ABRG53_0319(desC) ABRG53_4117(desC)
PGX: OA858_19820 OA858_21025
THEU: HPC62_07395
TOG: HNI00_21665
GLP: Glo7428_0279
CHON: NIES4102_36670
GDU: P0S91_10815
SYP: SYNPCC7002_A1989(desF)
SYV: AWQ23_09975
SYL: AWQ21_08640
LEP: Lepto7376_1352
SYNN: NIES970_02140(desF)
CYT: cce_2713(desC2)
CYC: PCC7424_2396 PCC7424_5567
PAGH: NIES204_39080
PPSU: NO713_02668(ADS3)
PRUN: PCC7821_04654(ADS3.2)
OAC: Oscil6304_5879
ONI: Osc7112_1415
MIC: Mic7113_0019
GEI: GEI7407_1700 GEI7407_1975
GVI: gll2866(desC)
GLJ: GKIL_2533
ANA: all4991(desC)
NPU: Npun_F3985
NOS: Nos7107_3198
NOP: Nos7524_2970
NON: NOS3756_43210(desC)
NFL: COO91_04376 COO91_08359 COO91_08859
NOE: CLI64_09460
NSH: GXM_03201 GXM_08165
NED: HUN01_13550
NPZ: ACX27_21710
AVA: Ava_2277
ACY: Anacy_3445
ANN: EH233_15760
CSG: Cylst_2748
RSIN: B6N60_05083
HBQ: QI031_25235 QI031_28570
CALO: Cal7507_5210
CALT: Cal6303_3526
CALN: NIES2098_27590 NIES2098_52280
CALS: NIES3974_07260
RIV: Riv7116_3630
FIS: FIS3754_15890
NSP: BMF81_01000(desC)
NSPH: BDGGKGIB_03242
AEE: IM676_09770
TOQ: HCG51_01375
ALAX: NIES50_20120 NIES50_58740(desC)
NCN: BZZ01_06585
CTHE: Chro_2505 Chro_2683
PLP: Ple7327_1440
SCS: Sta7437_3508
STAN: STA3757_05810 STA3757_30700
PIR: VN12_12505
RUL: UC8_07130
RML: FF011L_09560 FF011L_09860
MFF: MFFC18_17660
AHEL: Q31a_26480
LCRE: Pla8534_31300 Pla8534_47540
AAGG: ETAA8_55690
BVO: Pan97_30770
RLC: K227x_40160
SMAM: Mal15_08370
SNEP: Enr13x_64620
LPAV: PLANPX_3679
LLH: I41_29900 I41_35210
AMUC: Pan181_13530
PND: Pla175_17450
AMOB: HG15A2_27230 HG15A2_34320
BMEI: Spa11_31910
PLM: Plim_3820
PEH: Spb1_03340
PLS: VT03_01985
FMR: Fuma_02678 Fuma_06722
GMR: GmarT_27500 GmarT_54940
GIM: F1728_01260 F1728_17435
GPN: Pan110_26050 Pan110_55300
GFM: Enr17x_27970 Enr17x_54330
MRI: Mal4_16200
PLON: Pla110_08040
ACAF: CA12_37900
SVP: Pan189_29250
TPOL: Mal48_02420
CHYA: V22_41300
CCOS: Pan44_17350
PVAR: SH412_004229
CCOP: Mal65_30220
GES: VT84_37260
GMS: SOIL9_71080
ULI: ETAA1_62830
MCAD: Pan265_24440
ACA: ACP_1837
TRS: Terro_2288
TALB: FTW19_18235
EDG: H7846_12095
ADIN: H7849_11465 H7849_22425
ORP: MOP44_11465
 » show all
Reference
1  [PMID:16689682]
  Authors
Chintalapati S, Prakash JS, Gupta P, Ohtani S, Suzuki I, Sakamoto T, Murata N, Shivaji S
  Title
A novel Delta9 acyl-lipid desaturase, DesC2, from cyanobacteria acts on fatty acids esterified to the sn-2 position of glycerolipids.
  Journal
Biochem J 398:207-14 (2006)
DOI:10.1042/BJ20060039
  Sequence
[ag:CAF18426]
Other DBs
ExplorEnz - The Enzyme Database: 1.14.19.27
IUBMB Enzyme Nomenclature: 1.14.19.27
ExPASy - ENZYME nomenclature database: 1.14.19.27
BRENDA, the Enzyme Database: 1.14.19.27

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Gene (555)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (155)   
   KEGG MGENES (399)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (2)   
   InterPro (2)   
All databases (559)   

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