KEGG   ENZYME: 1.14.19.42
Entry
EC 1.14.19.42               Enzyme                                 
Name
palmitoyl-[glycerolipid] 7-desaturase;
FAD5
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
Sysname
1-acyl-2-palmitoyl-[glycerolipid],ferredoxin:oxygen oxidoreductase (7,8-cis-dehydrogenating)
Reaction(IUBMB)
a 1-acyl-2-palmitoyl-[glycerolipid] + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+ = a 1-acyl-2-[(7Z)-hexadec-7-enoyl]-[glycerolipid] + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O
Substrate
1-acyl-2-palmitoyl-[glycerolipid];
reduced ferredoxin [iron-sulfur] cluster [CPD:C00138];
O2 [CPD:C00007];
H+ [CPD:C00080]
Product
1-acyl-2-[(7Z)-hexadec-7-enoyl]-[glycerolipid];
oxidized ferredoxin [iron-sulfur] cluster [CPD:C00139];
H2O [CPD:C00001]
Comment
The enzyme introduces a cis double bond at carbon 7 of a palmitoyl group attached to the sn-2 position of glycerolipids. The enzyme from the plant Arabidopsis thaliana is specific for palmitate in monogalactosyldiacylglycerol.
History
EC 1.14.19.42 created 2015
Orthology
K20416  palmitoyl-[glycerolipid] 7-desaturase
Genes
ATH: AT3G15850(FAD5)
ALY: 110229983 9321178 9325649 9325650 9328382 9328398 9328399
CRB: 17892436 17900910
CSAT: 104739156 104739157 104739158 104739188 104743165 104745901 104745903 104745905 104754764 104754768 104764004 104764230 104765420 104767539 104778585 104780697 104780716
EUS: EUTSA_v10008319mg EUTSA_v10020955mg
BRP: 103836480 103836481 103836493 103838455 103843571 103844047 103844072 103859642 103859643 103859645 103869868 103870140
BNA: 106362210 106365702 106371147 106399300 106399393 106400080 106400093 106401219 106401310 106405307 106406041 106406784 106420060 106421809 106427048 106427049 106439426 106440507 106444038 106444040 111213569 125597254
BOE: 106292919 106293674 106295280 106295281 106295907 106308104 106310104 106310248 106310502 106330253 106333239 106334850 106345017
RSZ: 108813043 108819638 108820590 108820997 108821477 108853403 108853906 108854149 108855890 108857754 108861055 108862476 108863387 108863460 130495229 130497701 130498408 130509467 130512405
THJ: 104800890 104801541 104810511 104810512 104818022 104818023
CPAP: 110821049
CIT: 102621512
CIC: CICLE_v10025838mg
PVY: 116129461
MINC: 123212269 123218067
TCC: 18507067 18595268
GRA: 105770835
GHI: 107906461 107959660
GAB: 108450769
HSYR: 120131331 120133395
EGR: 104423180
GMX: 100527024(FAD5.2) 100786391(FAD5.1)
GSJ: 114418097 114422860
PVU: PHAVU_010G156200g
VRA: 106773545
VAR: 108320643
VUN: 114166036
VUM: 124829311
CCAJ: 109808338
APRC: 113857121
MTR: 11428408
TPRA: 123921538
CAM: 101495366
PSAT: 127105409
VVO: 131606129 131606130 131606132
LJA: Lj3g3v2187030.1(Lj3g3v2187030.1)
ADU: 107463855 107472877
AIP: 107619531
AHF: 112709787 112731432 112775888
LANG: 109342259 109356937
PCIN: 129291120
QSA: O6P43_018019 O6P43_027883
FVE: 101291166 101291746 101292289 101293512 101294219 101294512 101295463 101295541 101300165 101308020 101308027 101312700
RCN: 112164939 112167397 112170734 112176907 112178289 112179464 112180879 112181723 112181849 112181920 112183432 112184985 112184986 112185993 112187467 112189066 112189309 112189490 112189584 112189719 112190290 112192815 112199006 112199486 112200381 112200732 112201519 112201544 112201624 112203273
PPER: 18772708 18778303 18778345 18779213 18779474 18779518 18779543 18779930 18780081 18781236 18781372 18781603 18782662 18783085 18783148
PMUM: 103326614 103326615 103326617 103326775 103326927 103326928 103326929 103327012 103327101 103328085 103329342 103329364 103329366 103343077
PAVI: 110744430 110747628 110748519 110754346 110754435 110758308 110760789 110761594 110766712 110766717 110766718 110769023 110771357 110771426 110771438 110771445 110771454 110771455 110771461
PDUL: 117613718 117621922 117622610 117622846 117622848 117622849 117624531 117624533 117624944 117624945 117624988 117625034 117625058 117625460 117625461 117625463 117625465 117625467 117625563 117625763 117632083
MDM: 103400107 103402495 103404955 103410705 103418271 103427417 103429090 103429093 103429183 103437270 103438485 103442663 114823282
MSYL: 126582899 126583129 126588636 126589737 126589738 126601990 126609627 126611572 126612353 126612354 126612355 126614302 126634316 126634367
PXB: 103930863 103933423 103934587 103939078 103939868 103942467 103954981 103954982 103954983 103954985 103955282
ZJU: 107407905
MNT: 21408455
CSAV: 115705298 115705317
CSV: 101204869 101205118 101208515 101208755 101208999 101209243 101209490 101209735 101209978 101210229 101212673 101213475 105434479 116402852
CMO: 103487416 103487417 103491124 103492608 103492609 103494689 103494690 103494691 103494692 103494693 103494694 103494695 103494888 107990276
BHJ: 120067623 120067640 120069204 120071598 120072397 120080054 120081898 120086962 120089933 120089954 120089966 120090256 120090385 120090983
MCHA: 111013452 111014139 111020911 111020949 111020970 111020975 111020979 111021091 111021101 111021123 111022855 111022861 111022863 111024778 111025266
CMAX: 111479233 111479540 111479847 111479848 111479849 111479850 111480084 111480111 111485493 111488301 111488510 111493021 111493269 111493270 111497720
CMOS: 111452481 111452890 111452891 111452892 111455910 111456275 111457475 111457787 111457788 111457789 111457790 111457791 111457792 111457793 111457794 111457796 111457797 111458008 111458011 111458012 111460678 111461702
CPEP: 111779209 111787475 111788507 111788508 111788833 111788994 111790018 111790105 111790266 111790267 111790268 111790270 111790271 111791262 111791331 111791453 111791867 111791868 111791869 111791870 111795046 111807773 111807775
RCU: 8282342
JCU: 105634849
HBR: 110649623
MESC: 110613368
POP: 18103457 18103461 7455032
PEU: 105136814
PALZ: 118040840
JRE: 108998330
CILL: 122283899
CAVE: 132187499
QSU: 112028518 112034203 112034205
QLO: 115988903 115988904 115988905 115988909
TWL: 120007458 120010630 120010631 120011234 120011350 120011514
VVI: 100249077
VRI: 117922182
SLY: 101250586
SPEN: 107014969
SOT: 102601797
SSTN: 125860110
SDUL: 129896137
CANN: 107861959
LBB: 132632998
NTA: 107806561 107808120 107811213
NSY: 104223253
NTO: 104106571
NAU: 109231949
INI: 109150414 109150428 109150523 109150592 109150593 109179670
ITR: 115997352 115998692 115999251 116001335 116001345 116001360 116001367 116020021
SIND: 105158379
OEU: 111405181 111405182
EGT: 105975820
SSPL: 121795044 121796600 121797894 121797895 121802409
SMIL: 130989760 130992282 130992285
SHIS: 125205438 125208135 125211395
APAN: 127254557 127263211
HAN: 110864712 110866233 110872461 110882542 110882562 110884407 110885733 110902455 110902960 110910086 110910112 110910118 110910125 110910155 110912163 110932871 110935698 110935699 110935795 110937199
ECAD: 122587295 122597696 122597698 122597700 122602140 122605891 122607048 122607064 122607213 122608154 122608431 122608475
LSV: 111876957 111888922 111893616 111897837 111897843 111897845 111909589 111909659 111909664 111909691 111910108 111910198 111910199 111911750 111913179 111917517 111917535
CCAV: 112509500 112510978 112510981 112510983 112510985 112510986 112511283 112511613 112511636 112516350 112516351
DCR: 108219979
CSIN: 114255780
RVL: 131335405
AEW: 130750513 130788511
BVG: 104904554 104904555
SOE: 110784232 110784289
CQI: 110698651 110698652 110703239 110703240
ATRI: 130799229 130799237 130807575 130812261
MOF: 131158790 131158793
NNU: 104592471
MING: 122091646
PSOM: 113279876 113280223 113281724 113286089 113290443 113290480 113291367 113291368 113291396 113296000 113329050 113329249 113330576 113336169 113336191 113336208 113338928 113339013 113339108 113344373 113348362 113359211
AOF: 109828798
MSIN: 131256631
SMO: SELMODRAFT_413328 SELMODRAFT_45794
PPP: 112272776 112294672
CRE: CHLRE_04g217942v5 CHLRE_04g217945v5
VCN: VOLCADRAFT_89326
MNG: MNEG_11416
 » show all
Reference
1  [PMID:16666902]
  Authors
Kunst L, Browse J, Somerville C
  Title
A mutant of Arabidopsis deficient in desaturation of palmitic Acid in leaf lipids.
  Journal
Plant Physiol 90:943-7 (1989)
DOI:10.1104/pp.90.3.943
  Sequence
[ath:AT3G15850]
Reference
2  [PMID:15579662]
  Authors
Heilmann I, Mekhedov S, King B, Browse J, Shanklin J
  Title
Identification of the Arabidopsis palmitoyl-monogalactosyldiacylglycerol delta7-desaturase gene FAD5, and effects of plastidial retargeting of Arabidopsis desaturases on the fad5 mutant phenotype.
  Journal
Plant Physiol 136:4237-45 (2004)
DOI:10.1104/pp.104.052951
  Sequence
[ath:AT3G15850]
Other DBs
ExplorEnz - The Enzyme Database: 1.14.19.42
IUBMB Enzyme Nomenclature: 1.14.19.42
ExPASy - ENZYME nomenclature database: 1.14.19.42
BRENDA, the Enzyme Database: 1.14.19.42

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