KEGG   ENZYME: 1.14.19.63
Entry
EC 1.14.19.63               Enzyme                                 
Name
pseudobaptigenin synthase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
Sysname
calycosin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (methylenedioxy-bridge-forming)
Reaction(IUBMB)
(1) calycosin + [reduced NADPH---hemoprotein reductase] + O2 = pseudobaptigenin + [oxidized NADPH---hemoprotein reductase] + 2 H2O [RN:R07745];
(2) pratensein + [reduced NADPH-hemoprotein reductase] + O2 = 5-hydroxypseudobaptigenin + [oxidized NADPH---hemoprotein reductase] + 2 H2O [RN:R09602]
Reaction(KEGG)
R07745 R09602
Substrate
calycosin [CPD:C01562];
[reduced NADPH---hemoprotein reductase] [CPD:C03024];
O2 [CPD:C00007];
pratensein [CPD:C10520];
[reduced NADPH-hemoprotein reductase]
Product
pseudobaptigenin [CPD:C10522];
[oxidized NADPH---hemoprotein reductase] [CPD:C03161];
H2O [CPD:C00001];
5-hydroxypseudobaptigenin [CPD:C19727]
Comment
A cytochrome P-450 (heme-thiolate) enzyme catalysing an oxidative reaction that does not incorporate oxygen into the product. Catalyses a step in the biosynthesis of (-)-maackiain, the main pterocarpan phytoalexin in chickpea (Cicer arietinum).
History
EC 1.14.19.63 created 2011 as EC 1.14.21.8, transferred 2018 to EC 1.14.19.63
Pathway
ec00943  Isoflavonoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Reference
1
  Authors
Clemens S., Barz W.
  Title
Cytochrome P450-dependent methylenedioxy bridge formation in Cicer arietinum.
  Journal
Phytochemistry 41:457-460 (1996)
Other DBs
ExplorEnz - The Enzyme Database: 1.14.19.63
IUBMB Enzyme Nomenclature: 1.14.19.63
ExPASy - ENZYME nomenclature database: 1.14.19.63
BRENDA, the Enzyme Database: 1.14.19.63

  All links  
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG REACTION (2)   
   KEGG RCLASS (1)   
All databases (15)   

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