KEGG ENZYME: 1.14.19.76

KEGG

ENZYME: 1.14.19.76

Entry

EC 1.14.19.76               Enzyme

Name

flavone synthase II;
CYP93B16 (gene name);
CYP93G1 (gene name);
FNS II

Class

Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water

Sysname

flavanone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (flavone-forming)

Reaction(IUBMB)

a flavanone + [reduced NADPH---hemoprotein reductase] + O2 = a flavone + [oxidized NADPH---hemoprotein reductase] + 2 H2O [RN:R12276]

Reaction(KEGG)

R12276 > R12277 R12278 R12279

Substrate

flavanone [CPD:C00766];
[reduced NADPH---hemoprotein reductase] [CPD:C03024];
O2 [CPD:C00007]

Product

flavone [CPD:C15608];
[oxidized NADPH---hemoprotein reductase] [CPD:C03161];
H2O [CPD:C00001]

Comment

A cytochrome P-450 (heme-thiolate) protein found in plants. The rice enzyme channels flavanones to the biosynthesis of tricin O-linked conjugates. cf. EC 1.14.20.5, flavone synthase I.

History

EC 1.14.19.76 created 2018

Pathway

Flavonoid biosynthesis

Isoflavonoid biosynthesis

Metabolic pathways

Biosynthesis of secondary metabolites

Orthology

flavone synthase II

flavone synthase II

Genes

CIT:	102607946 102609972 102611200

CIC:	CICLE_v10019810mg CICLE_v10019811mg

PVY:	116113484 116113521 116129556 116145436

123203073

TCC:	18593008 18593084

GRA:

105781200

GHI:	107895096 107919519

GAB:	108462515 108463531

120113983 120124673

DZI:	111284583 111315053

EGR:	104432774 104432776

GMX:	100783503(FNSII-1) 100784036(FNSII-2)

GSJ:

114379343

PVU:	PHAVU_011G068100g

VAR:

108323455

VUN:

114169631

109798920

113857422 113859174

MTR:	25485387 25492470 25492471

123918495

CAM:

101511254

127105441

VVO:	131601961 131607001 131656934

ADU:

107477091

AIP:

107634112

AHF:	112736589 112768987

109351612 109351614

129295228 129313542

RCU:	8286099 8286101

HBR:	110637536 110639710 110670394

110613186 110625897

POP:	18098816 7473876

PEU:

105124985

118053247

LBB:

132626350

105170377

OEU:

111402974

EGT:	105949064 105949083

121740953 121743927

131000745

125191117

127253820 127253839

HAN:

110873193

122587139

LSV:

111905568

112518085

114286595 114296673 114307649 114322163

RVL:

131314795

MOF:

131149350

OSA:

4334886

Os04t0101400-01(Os04g0101400)

OBR:	102714554 102716963

OGL:

127770153

BDI:

100841298

ATS:

109733276

TDC:	119352891 119361919

123043285 123051157 123187112

TUA:

125535225

127331054

LRD:

124677445

SBI:

8056944

ZMA:	103641445 103642652 103646891

101761949

SVS:

117862541

120639519 120639522 120681960

112900040

Reference

1 [PMID:10652133]

Authors

Martens S, Forkmann G

Title

Cloning and expression of flavone synthase II from Gerbera hybrids.

Journal

Plant J 20:611-8 (1999)
DOI:10.1046/j.1365-313X.1999.00636.x

Sequence

Reference

2 [PMID:20132953]

Authors

Fliegmann J, Furtwangler K, Malterer G, Cantarello C, Schuler G, Ebel J, Mithofer A

Title

Flavone synthase II (CYP93B16) from soybean (Glycine max L.).

Journal

Phytochemistry 71:508-14 (2010)
DOI:10.1016/j.phytochem.2010.01.007

Sequence

[gmx:100783503]

Reference

3 [PMID:24843076]

Authors

Lam PY, Zhu FY, Chan WL, Liu H, Lo C

Title

Cytochrome P450 93G1 Is a Flavone Synthase II That Channels Flavanones to the Biosynthesis of Tricin O-Linked Conjugates in Rice.

Journal

Plant Physiol 165:1315-1327 (2014)
DOI:10.1104/pp.114.239723

Sequence

Other DBs

ExplorEnz - The Enzyme Database:

IUBMB Enzyme Nomenclature:

ExPASy - ENZYME nomenclature database:

BRENDA, the Enzyme Database:

DBGET integrated database retrieval system