KEGG   ENZYME: 1.14.99.14
Entry
EC 1.14.99.14               Enzyme                                 
Name
progesterone 11alpha-monooxygenase;
progesterone 11alpha-hydroxylase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
Miscellaneous
Sysname
progesterone,hydrogen-donor:oxygen oxidoreductase (11alpha-hydroxylating)
Reaction(IUBMB)
progesterone + reduced acceptor + O2 = 11alpha-hydroxyprogesterone + acceptor + H2O [RN:R02214]
Reaction(KEGG)
R02214
Substrate
progesterone [CPD:C00410];
reduced acceptor [CPD:C00030];
O2 [CPD:C00007]
Product
11alpha-hydroxyprogesterone [CPD:C03747];
acceptor [CPD:C00028];
H2O [CPD:C00001]
History
EC 1.14.99.14 created 1972
Pathway
ec00140  Steroid hormone biosynthesis
Reference
1  [PMID:5417182]
  Authors
Shibahara M, Moody JA, Smith LL.
  Title
Microbial hydroxylations. V. 11-alpha-hydroxylation of progesterone by cell-free preparations of Aspergillus ochraceus.
  Journal
Biochim Biophys Acta 202:172-9 (1970)
DOI:10.1016/0005-2760(70)90228-6
Other DBs
ExplorEnz - The Enzyme Database: 1.14.99.14
IUBMB Enzyme Nomenclature: 1.14.99.14
ExPASy - ENZYME nomenclature database: 1.14.99.14
BRENDA, the Enzyme Database: 1.14.99.14
CAS: 37256-77-2

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Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
All databases (10)   

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