KEGG   ENZYME: 1.14.99.26
Entry
EC 1.14.99.26               Enzyme                                 
Name
2-hydroxypyridine 5-monooxygenase;
2-hydroxypyridine oxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
Miscellaneous
Sysname
2-hydroxypyridine,hydrogen-donor:oxygen oxidoreductase (5-hydroxylating)
Reaction(IUBMB)
2-hydroxypyridine + reduced acceptor + O2 = 2,5-dihydroxypyridine + acceptor + H2O [RN:R03206]
Reaction(KEGG)
R03206
Substrate
2-hydroxypyridine [CPD:C02502];
reduced acceptor [CPD:C00030];
O2 [CPD:C00007]
Product
2,5-dihydroxypyridine [CPD:C01059];
acceptor [CPD:C00028];
H2O [CPD:C00001]
Comment
Also oxidizes 2,5-dihydroxypyridine, but does not act on 3-hydroxypyridine, 4-hydroxypyridine or 2,6-dihydroxypyridine.
History
EC 1.14.99.26 created 1989
Reference
1
  Authors
Sharma, M.L., Kaul, S.M. and Shukla, O.P.
  Title
Metabolism of 2-hydroxypyridine by Bacillus brevis (INA).
  Journal
Biol Membr 9:43-52 (1984)
Other DBs
ExplorEnz - The Enzyme Database: 1.14.99.26
IUBMB Enzyme Nomenclature: 1.14.99.26
ExPASy - ENZYME nomenclature database: 1.14.99.26
BRENDA, the Enzyme Database: 1.14.99.26
CAS: 96779-45-2

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