Oxidoreductases;
Oxidizing metal ions;
With oxygen as acceptor
BRITE hierarchy

manganese(II):oxygen oxidoreductase

4 Mn2+ + 2 O2 + 4 H2O = 4 MnIVO2 + 8 H+ (overall reaction) [RN:R11880];
(1a) 4 Mn2+ + O2 + 4 H+ = 4 Mn3+ + 2 H2O [RN:R11881];
(1b) 4 Mn3+ + O2 + 6 H2O = 4 MnIVO2 + 12 H+ [RN:R11882]

R11880 R11881 R11882
Reaction

Mn2+ [CPD:C19610];
O2 [CPD:C00007];
H2O [CPD:C00001];
H+ [CPD:C00080];
Mn3+ [CPD:C19611]

The enzyme, which belongs to the multicopper oxidase family, is found in many bacterial strains. It oxidizes soluble manganese(II) to insoluble manganese(IV) oxides. Since the enzyme is localized to the outer surface of the cell, its activity usually results in encrustation of the cells by the oxides. The physiological function of bacterial manganese(II) oxidation remains unclear.

EC 1.16.3.3 created 2017

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2  [PMID:12420165]

3  [PMID:17359266]

4  [PMID:23124227]

5  [PMID:23577125]