KEGG   ENZYME: 1.2.1.15
Entry
EC 1.2.1.15                 Enzyme                                 
Name
malonate-semialdehyde dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
Sysname
3-oxopropanoate:NAD(P)+ oxidoreductase
Reaction(IUBMB)
3-oxopropanoate + NAD(P)+ + H2O = malonate + NAD(P)H + 2 H+ [RN:R01604 R01607]
Reaction(KEGG)
R01604 R01607
Substrate
3-oxopropanoate [CPD:C00222];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Product
malonate [CPD:C00383];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.2.1.15 created 1965
Pathway
ec00410  beta-Alanine metabolism
Reference
1  [PMID:13727610]
  Authors
NAKAMURA K, BERNHEIM F.
  Title
Studies on malonic semialdehyde dehydrogenase from Pseudomonas aeruginosa.
  Journal
Biochim Biophys Acta 50:147-52 (1961)
DOI:10.1016/0006-3002(61)91071-X
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.15
IUBMB Enzyme Nomenclature: 1.2.1.15
ExPASy - ENZYME nomenclature database: 1.2.1.15
BRENDA, the Enzyme Database: 1.2.1.15
CAS: 9028-94-8

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