Entry
Name
salicylaldehyde dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
salicylaldehyde:NAD+ oxidoreductase
Reaction(IUBMB)
salicylaldehyde + NAD+ + H2O = salicylate + NADH + 2 H+ [RN:
R02941 ]
Reaction(KEGG)
Substrate
Product
Comment
Involved in the naphthalene degradation pathway in some bacteria.
History
EC 1.2.1.65 created 2000, modified 2011
Pathway
ec01120 Microbial metabolism in diverse environments
Orthology
K00152 salicylaldehyde dehydrogenase
Genes
Taxonomy
Reference
Authors
Eaton RW, Chapman PJ
Title
Bacterial metabolism of naphthalene: construction and use of recombinant bacteria to study ring cleavage of 1,2-dihydroxynaphthalene and subsequent reactions.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.65
ExPASy - ENZYME nomenclature database: 1.2.1.65
UM-BBD (Biocatalysis/Biodegradation Database): 1.2.1.65