KEGG ENZYME: 1.2.1.82

ENZYME: 1.2.1.82

Entry

EC 1.2.1.82                 Enzyme

Name

beta-apo-4'-carotenal dehydrogenase;
beta-apo-4'-carotenal oxygenase;
YLO-1;
carD (gene name)

Class

Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor

Sysname

4'-apo-beta,psi-carotenal:NAD+ oxidoreductase

Reaction(IUBMB)

4'-apo-beta,psi-caroten-4'-al + NAD+ + H2O = neurosporaxanthin + NADH + 2 H+ [RN:R09783]

Reaction(KEGG)

R09783

Substrate

4'-apo-beta,psi-caroten-4'-al [CPD:C19892];
NAD+ [CPD:C00003];
H2O [CPD:C00001]

Product

neurosporaxanthin [CPD:C08607];
NADH [CPD:C00004];
H+ [CPD:C00080]

Comment

Neurosporaxanthin is responsible for the orange color of of Neurospora.

History

EC 1.2.1.82 created 2011, modified 2023

Pathway

ec00906

Carotenoid biosynthesis

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K17819

beta-apo-4'-carotenal oxygenase

Genes

NCR:	NCU04013(ylo-1)

NTE:	NEUTE1DRAFT140784(NEUTE1DRAFT_140784)

SMP:	SMAC_06187

PAN:	PODANSg936

PBEL:

QC761_402650(HFD1)

PPSD:

QC762_402650(HFD1)

PPSP:

QC763_402650(HFD1)

PPSA:

QC764_402650(HFD1)

TTT:	THITE_2110821

MTM:	MYCTH_2307429

CTHR:

CTHT_0045070

MGR:

MGG_07270

PPEI:

PpBr36_01911

PGRI:

PgNI_07699

TMN:	UCRPA7_4168

SSCK:

SPSK_05142

FGR:	FGSG_09960

FPU:	FPSE_03856

FPOA:

FPOAC1_003036

FVN:	FVRRES_03365

FVR:	FVEG_02675

FOX:	FOXG_05463

NHE:	NECHADRAFT_61128

FFC:	NCS54_00694000

FKR:	NCS57_00734000

FMU:	J7337_005591

TRE:	TRIREDRAFT_74502

TRR:	M419DRAFT_101618

MAW:

MAC_03864

MAJ:

MAA_02951

PCHM:

VFPPC_07340

CMT:

CCM_09155

AMUS:

LMH87_004714

PLJ:	VFPFJ_08615

PTKZ:

JDV02_006758(HFD1)

VAL:	VDBG_04258

VDA:	VDAG_01487

CFJ:	CFIO01_01475 CFIO01_11498

CLUP:

CLUP02_09323 CLUP02_10229

CHIG:

CH63R_09346

SAPO:

SAPIO_CDS10721

ELA:	UCREL1_1920

PFY:	PFICI_06386

SSL:	SS1G_10799

BFU:	BCIN_04g05680(Bchfd1)

MBE:

MBM_07141

PSCO:

LY89DRAFT_647434

GLZ:	GLAREA_10198

ANI:	ANIA_05644

AFM:	AFUA_4G13500

ACT:	ACLA_052470

NFI:	NFIA_102870

AOR:	AO090009000222

ANG:	An01g09260

AFV:	AFLA_011134

ALUC:

AKAW2_20980A

ACHE:

ACHE_10403A

APUU:

APUU_41014A APUU_60997S

PCS:	N7525_005851

PDP:	PDIP_43940

POU:	POX_a01679

TMF:	EYB26_004096 EYB26_004953

TRG:	TRUGW13939_10770

CIM:	CIMG_00543

CPW:	CPC735_056920

URE:	UREG_00562

PBL:	PAAG_06961

PBN:	PADG_01495

ABE:

ARB_07806

TVE:

TRV_07386

AJE:	HCAG_07063

BGH:	BDBG_04911

PNO:	SNOG_05777

PTE:

PTT_13172

BZE:	COCCADRAFT_101773

BSC:	COCSADRAFT_32828

BOR:	COCMIDRAFT_108997

AALT:

CC77DRAFT_926989

ARAB:

EKO05_0010296

ZTR:	MYCGRDRAFT_98253

PFJ:	MYCFIDRAFT_135796

FFU:	CLAFUR5_12135

CBET:

CB0940_12179

BCOM:

BAUCODRAFT_38526

NPA:	UCRNP2_5491

TML:	GSTUM_00011869001

FME:	FOMMEDRAFT_147683

RSX:	RhiXN_00669

» show all

Reference

1 [PMID:18627463]

Authors

Estrada AF, Youssar L, Scherzinger D, Al-Babili S, Avalos J

Title

The ylo-1 gene encodes an aldehyde dehydrogenase responsible for the last reaction in the Neurospora carotenoid pathway.

Journal

Mol Microbiol 69:1207-20 (2008)
DOI:10.1111/j.1365-2958.2008.06349.x

Sequence

[ncr:NCU04013]

Reference

2 [PMID:21749649]

Authors

Diaz-Sanchez V, Estrada AF, Trautmann D, Al-Babili S, Avalos J

Title

The gene carD encodes the aldehyde dehydrogenase responsible for neurosporaxanthin biosynthesis in Fusarium fujikuroi.

Journal

FEBS J 278:3164-76 (2011)
DOI:10.1111/j.1742-4658.2011.08242.x

Sequence

[ag:CCA63431]

Other DBs

ExplorEnz - The Enzyme Database:

1.2.1.82

IUBMB Enzyme Nomenclature:

1.2.1.82

ExPASy - ENZYME nomenclature database:

1.2.1.82

BRENDA, the Enzyme Database:

1.2.1.82

DBGET integrated database retrieval system