Entry
Name
aldehyde dehydrogenase (FAD-independent);
aldehyde oxidase;
aldehyde oxidoreductase;
Mop;
AORDd
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With unknown physiological acceptors
BRITE hierarchy
Sysname
aldehyde:acceptor oxidoreductase (FAD-independent)
Reaction(IUBMB)
an aldehyde + H2O + acceptor = a carboxylate + reduced acceptor [RN:
R00544 ]
Reaction(KEGG)
Substrate
Product
Comment
Belongs to the xanthine oxidase family of enzymes. The enzyme from Desulfovibrio sp. contains a molybdenum-molybdopterin-cytosine dinucleotide (MCD) complex and two types of [2Fe-2S] cluster per monomer, but does not contain FAD.
History
EC 1.2.99.7 created 2004
Orthology
K07469 aldehyde oxidoreductase
Genes
PACE : A6070_10775 A6070_14425
DMS : E8L03_03670 E8L03_11880
DPI : BN4_11183 BN4_11879(mop)
PSEL : GM415_09125 GM415_15685
PPOR : JCM14722_31400(mop)
PNW : SYK_13630(mop_1) SYK_22350(mop_2)
PTHE : LF599_07025 LF599_12100
DEO : CAY53_03230 CAY53_03300
DAT : HRM2_07080(mop1) HRM2_38770(mop2)
DOV : DSCO28_12970(mop_1) DSCO28_16460(mop_2) DSCO28_22590 DSCO28_54420(mop_3)
DWD : DSCW_31270(mop) DSCW_61540
DTI : Desti_0720 Desti_1799
CLJ : CLJU_c24050 CLJU_c24130
CLOS : DMR38_12345 DMR38_12385
RGV : NQ502_15120 NQ502_17970
PETR : QKW49_07245 QKW49_23100
DOR : Desor_1273 Desor_3016
DAI : Desaci_2677 Desaci_2707
DMI : Desmer_1171 Desmer_1863
FWA : DCMF_02040 DCMF_08470 DCMF_14090 DCMF_14115 DCMF_21835 DCMF_26870
DGI : Desgi_0268 Desgi_0270 Desgi_2922 Desgi_3899
AWO : Awo_c03890(mop1) Awo_c14980(mop3) Awo_c27190
BPRO : PMF13cell1_01056(mop_1)
CSCI : HDCHBGLK_02491(pucD)
PDC : CDIF630_03469(xdhA5)
CDL : CDR20291_3033(xdhA3)
CPOR : BED41_02500 BED41_02975 BED41_11740
AMO : Anamo_0983 Anamo_1057
» show all
Taxonomy
Reference
Authors
Uchida H, Kondo D, Yamashita A, Nagaosa Y, Sakurai T, Fujii Y, Fujishiro K, Aisaka K, Uwajima T.
Title
Purification and characterization of an aldehyde oxidase from Pseudomonas sp. KY 4690.
Journal
Reference
Authors
Duarte RO, Archer M, Dias JM, Bursakov S, Huber R, Moura I, Romao MJ, Moura JJ
Title
Biochemical/spectroscopic characterization and preliminary X-ray analysis of a new aldehyde oxidoreductase isolated from Desulfovibrio desulfuricans ATCC 27774.
Journal
Reference
Authors
Andrade SL, Brondino CD, Feio MJ, Moura I, Moura JJ
Title
Aldehyde oxidoreductase activity in Desulfovibrio alaskensis NCIMB 13491 EPR assignment of the proximal [2Fe-2S] cluster to the Mo site.
Journal
Reference
Authors
Romao MJ, Archer M, Moura I, Moura JJ, LeGall J, Engh R, Schneider M, Hof P, Huber R
Title
Crystal structure of the xanthine oxidase-related aldehyde oxido-reductase from D. gigas.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.2.99.7
ExPASy - ENZYME nomenclature database: 1.2.99.7