KEGG   ENZYME: 1.20.99.1
Entry
EC 1.20.99.1                Enzyme                                 
Name
arsenate reductase (donor);
arsenate:(acceptor) oxidoreductase
Class
Oxidoreductases;
Acting on phosphorus or arsenic in donors;
With unknown physiological acceptors
Sysname
arsenate:acceptor oxidoreductase
Reaction(IUBMB)
arsenite + acceptor = arsenate + reduced acceptor [RN:R05752]
Reaction(KEGG)
R05752
Substrate
arsenite [CPD:C06697];
acceptor [CPD:C00028]
Product
arsenate [CPD:C11215];
reduced acceptor [CPD:C00030]
Comment
Benzyl viologen can act as an acceptor. Unlike EC 1.20.4.1, arsenate reductase (glutaredoxin), reduced glutaredoxin cannot serve as a reductant.
History
EC 1.20.99.1 created 2000 as EC 1.97.1.6, transferred 2001 to EC 1.20.99.1
Reference
1  [PMID:9738904]
  Authors
Krafft T, Macy JM.
  Title
Purification and characterization of the respiratory arsenate reductase of Chrysiogenes arsenatis.
  Journal
Eur J Biochem 255:647-53 (1998)
DOI:10.1046/j.1432-1327.1998.2550647.x
Reference
2  [PMID:10649963]
  Authors
Radabaugh TR, Aposhian HV.
  Title
Enzymatic reduction of arsenic compounds in mammalian systems: reduction of arsenate to arsenite by human liver arsenate reductase.
  Journal
Chem Res Toxicol 13:26-30 (2000)
DOI:10.1021/tx990115k
Other DBs
ExplorEnz - The Enzyme Database: 1.20.99.1
IUBMB Enzyme Nomenclature: 1.20.99.1
ExPASy - ENZYME nomenclature database: 1.20.99.1
BRENDA, the Enzyme Database: 1.20.99.1
CAS: 146907-46-2

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