KEGG   ENZYME: 1.3.1.103
Entry
EC 1.3.1.103                Enzyme                                 
Name
2-haloacrylate reductase;
CAA43 (gene name)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
(S)-2-chloropropanoate:NADP+ oxidoreductase
Reaction(IUBMB)
(S)-2-chloropropanoate + NADP+ = 2-chloroacrylate + NADPH + H+ [RN:R10418]
Reaction(KEGG)
R10418
Substrate
(S)-2-chloropropanoate [CPD:C20608];
NADP+ [CPD:C00006]
Product
2-chloroacrylate [CPD:C20609];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme acts in the degradation pathway of unsaturated organohalogen compounds by the bacterium Burkholderia sp. WS.
History
EC 1.3.1.103 created 2013
Orthology
K21839  2-haloacrylate reductase
Reference
1  [PMID:15781461]
  Authors
Kurata A, Kurihara T, Kamachi H, Esaki N
  Title
2-Haloacrylate reductase, a novel enzyme of the medium chain dehydrogenase/reductase superfamily that catalyzes the reduction of a carbon-carbon double bond of unsaturated organohalogen compounds.
  Journal
J Biol Chem 280:20286-91 (2005)
DOI:10.1074/jbc.M414605200
  Sequence
[ag:BAD91551]
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.103
IUBMB Enzyme Nomenclature: 1.3.1.103
ExPASy - ENZYME nomenclature database: 1.3.1.103
BRENDA, the Enzyme Database: 1.3.1.103

  All links  
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
Protein sequence (438)   
   UniProt (437)   
   SWISS-PROT (1)   
DNA sequence (388)   
   GenBank (200)   
   EMBL (188)   
Protein domain (6)   
   InterPro (6)   
All databases (841)   

Download RDF
DBGET integrated database retrieval system