KEGG   ENZYME: 1.3.1.124
Entry
EC 1.3.1.124                Enzyme                                 
Name
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing];
SPS19 (gene name);
DECR1 (gene name);
DECR2 (gene name);
Delta2,Delta4-dienoyl-CoA reductase (ambiguous)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
(3E)-3-enoyl-CoA:NADP+ 4-oxidoreductase
Reaction(IUBMB)
(1) a (3E)-3-enoyl-CoA + NADP+ = a (2E,4E)-2,4-dienoyl-CoA + NADPH + H+ [RN:R12629];
(2) a (3E)-3-enoyl-CoA + NADP+ = a (2E,4Z)-2,4-dienoyl-CoA + NADPH + H+ [RN:R12630]
Reaction(KEGG)
R12629 R12630
Substrate
(3E)-3-enoyl-CoA [CPD:C05067];
NADP+ [CPD:C00006]
Product
(2E,4E)-2,4-dienoyl-CoA [CPD:C04512];
NADPH [CPD:C00005];
H+ [CPD:C00080];
(2E,4Z)-2,4-dienoyl-CoA [CPD:C22258]
Comment
This enzyme, characterized from eukaryotic organisms, catalyses the reduction of either (2E,4E)-2,4-dienoyl-CoA or (2E,4Z)-2,4-dienoyl-CoA to (3E)-3-enoyl-CoA. The best substrates for the enzyme from bovine liver have a chain-length of 8 or 10 carbons. Mammals possess both mitochondrial and peroxisomal variants of this enzyme. cf. EC 1.3.1.34, 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing].
History
EC 1.3.1.124 created 2020
Orthology
K13236  2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial
K13237  2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], peroxisomal
Genes
HSA: 1666(DECR1) 26063(DECR2)
PTR: 100608945 112204143 736777(DECR1)
PPS: 100985245(DECR1) 100989760(DECR2)
GGO: 101126321(DECR1) 101152371(DECR2)
PON: 100172330(DECR2) 100448925(DECR1)
NLE: 100585734(DECR1) 100585845(DECR2)
HMH: 116462327(DECR2) 116813399(DECR1)
MCC: 695540(DECR2) 696035(DECR1)
MCF: 102144225(DECR1) 102145768(DECR2)
MTHB: 126944860 126961843
MNI: 105485914(DECR2) 105497282(DECR1)
CSAB: 103225407(DECR2) 103237099(DECR1)
CATY: 105572964(DECR1) 105574485(DECR2)
PANU: 100137284(DECR2) 101007820(DECR1)
TGE: 112614183(DECR2) 112629871(DECR1)
MLEU: 105541548(DECR1)
RRO: 104654648(DECR1) 104676958(DECR2)
RBB: 108521129(DECR2) 108526907(DECR1)
TFN: 117079485(DECR1) 117097911(DECR2)
PTEH: 111524040(DECR2) 111549665(DECR1)
CANG: 105508237(DECR1) 105524713(DECR2)
CJC: 100393816(DECR2) 100400830(DECR1)
SBQ: 101032159(DECR1) 101050434(DECR2)
CIMI: 108290857(DECR2) 108310874(DECR1)
CSYR: 103249919(DECR2) 103262893(DECR1)
MMUR: 105856269(DECR2) 105870550(DECR1)
LCAT: 123631387(DECR2) 123644458(DECR1)
PCOQ: 105809780(DECR1) 105822609(DECR2)
OGA: 100963146(DECR1) 100966778(DECR2)
MMU: 26378(Decr2) 67460(Decr1)
MCAL: 110284239(Decr2) 110293087(Decr1)
MPAH: 110338200(Decr2) 110338860(Decr1)
RNO: 117543(Decr1) 64461(Decr2)
MCOC: 116078584(Decr2) 116088046(Decr1)
ANU: 117698490(Decr1) 117711546(Decr2)
MUN: 110545064(Decr1) 110548715(Decr2)
CGE: 100753128(Decr1) 100759323(Decr2)
MAUA: 101825296(Decr1) 101829464(Decr2)
PROB: 127219483(Decr2) 127229279 127232482(Decr1)
PLEU: 114681238(Decr2) 114694598(Decr1)
MORG: 121451660(Decr1) 121463789(Decr2)
MFOT: 126496936 126515719
AAMP: 119811929(Decr2) 119825930(Decr1)
NGI: 103729535(Decr1) 103752377(Decr2)
HGL: 101720323(Decr2) 101721782(Decr1)
CPOC: 100713979(Decr2) 100715286(Decr1)
CCAN: 109681383 109690121(Decr1) 109694652(Decr2)
DORD: 105981793(Decr2) 105982743(Decr1)
DSP: 122098156(Decr2) 122102455(Decr1)
PLOP: 125340748(Decr2) 125360716(Decr1)
NCAR: 124986868
MMMA: 107142489(Decr1) 107146786(Decr2)
OCU: 100348851 100352241 103347237
OPI: 101522993(DECR1) 101534172(DECR2)
TUP: 102471220(DECR2) 102475445(DECR1) 102492775
GVR: 103595719(DECR2) 103601773(DECR1)
CFA: 100688128(DECR2) 477938(DECR1)
CLUD: 112640634(DECR2) 112650713(DECR1)
VVP: 112909058(DECR2) 112914054 112930908(DECR1)
VLG: 121486921(DECR2) 121498775(DECR1)
NPO: 129495665(DECR1) 129519392(DECR2)
AML: 100473271(DECR2) 100481266(DECR1)
UMR: 103661415(DECR1) 103668732(DECR2)
UAH: 113245374(DECR2) 113252959(DECR1)
UAR: 123783323(DECR2) 123797901(DECR1)
ELK: 111146553 111156214
LLV: 125090917 125097967
MPUF: 101687475(DECR1) 101694106(DECR2)
MNP: 132014145(DECR1) 132027094(DECR2)
MLK: 131819232(DECR2) 131826624(DECR1)
NVS: 122895672(DECR2) 122904457(DECR1)
ORO: 101375736(DECR1) 101376230(DECR2)
EJU: 114213514(DECR1) 114215739(DECR2)
ZCA: 113911506(DECR1) 113933677(DECR2)
MLX: 118014999(DECR1) 118021655(DECR2)
NSU: 110578683(DECR1) 110588063(DECR2) 110588256
LWW: 102733951(DECR2) 102748446
FCA: 101087299(DECR1) 101088540(DECR2)
PYU: 121019786(DECR2) 121042674(DECR1)
PCOO: 112859313(DECR1) 112860147(DECR2)
PBG: 122471929(DECR2) 122495574(DECR1)
PVIV: 125154556(DECR2) 125156336(DECR1)
LRUF: 124519048 124525510
PTG: 102950586(DECR1) 102970768(DECR2)
PPAD: 109259629(DECR2) 109269462(DECR1)
PUC: 125924807 125928391
AJU: 106977360 106984789
HHV: 120225181(DECR2) 120237333(DECR1)
BTA: 509952(DECR1) 768256(DECR2)
BOM: 102267072(DECR2) 102276962(DECR1)
BIU: 109568554(DECR1) 109578698(DECR2)
BBUB: 102392805(DECR2) 102404940(DECR1)
BBIS: 104989253(DECR2) 105004464(DECR1)
CHX: 102186732(DECR2) 102191818(DECR1)
OAS: 101110109(DECR2) 101115040(DECR1)
BTAX: 128059344(DECR1) 128070466(DECR2)
ODA: 120854962(DECR2) 120878512(DECR1)
CCAD: 122433489(DECR2) 122451123(DECR1)
MBEZ: 129545187(DECR2) 129560449(DECR1)
SSC: 100524368(DECR2) 503544(DECR1)
CFR: 102506320(DECR1) 102522579(DECR2)
CBAI: 105064733(DECR1) 105065733(DECR2)
CDK: 105087539(DECR1) 105098427(DECR2)
VPC: 102528749(DECR1) 102533908(DECR2)
BACU: 103003311(DECR2) 103018125(DECR1)
BMUS: 118881277(DECR2) 118883530(DECR1)
LVE: 103083575(DECR2) 103090523(DECR1)
OOR: 101271181(DECR2) 101276216(DECR1)
DLE: 111180437(DECR1) 111185099(DECR2)
PCAD: 102982907(DECR1) 102984684(DECR2)
PSIU: 116740309(DECR2) 116742479(DECR1)
NASI: 112406864(DECR1) 112409489(DECR2)
ECB: 100053423(DECR1) 100065146(DECR2)
EPZ: 103543686 103564116(DECR2)
EAI: 106836165(DECR2) 106838975(DECR1)
MYB: 102239975(DECR1) 102249531(DECR2)
MYD: 102760553(DECR2) 102770411(DECR1)
MMYO: 118652899(DECR2) 118670476(DECR1)
MLF: 102419764(DECR2) 102433528(DECR1)
PKL: 118718484(DECR1) 118731497(DECR2)
EFUS: 103300769(DECR2) 103301865(DECR1)
MNA: 107526478(DECR1) 107545463(DECR2)
DRO: 112298258(DECR2) 112310308(DECR1)
SHON: 118978854(DECR2) 118989287(DECR1)
AJM: 119058255(DECR2) 119060054(DECR1)
PDIC: 114498841(DECR2) 114501393(DECR1)
PHAS: 123820976(DECR1) 123825700(DECR2)
MMF: 118631588(DECR1) 118642269(DECR2)
PPAM: 129081251(DECR2) 129088207(DECR1)
HAI: 109385940(DECR2) 109387599(DECR1)
RFQ: 117019549(DECR2) 117033657(DECR1)
PALE: 102877745(DECR2) 102882014(DECR1)
PGIG: 120614248(DECR1) 120620168(DECR2)
PVP: 105303255(DECR2) 105304149(DECR1)
RAY: 107506135(DECR2) 107507471(DECR1)
MJV: 108384590(DECR2) 108394802(DECR1)
TOD: 119239919(DECR1) 119242067(DECR2)
SARA: 101547921(DECR1) 101550833(DECR2)
SETR: 126000837(DECR2) 126020626(DECR1)
LAV: 100664822(DECR1) 100676256(DECR2)
TMU: 101346627 101361590
ETF: 101649088(DECR2) 101658933(DECR1)
DNM: 101416215 101420796(DECR1)
MDO: 100020025(DECR2) 100029422(DECR1)
GAS: 123230944(DECR2) 123240661(DECR1)
SHR: 100915519(DECR1) 100924629(DECR2)
AFZ: 127542961 127544271
PCW: 110203269(DECR1) 110221885(DECR2)
OAA: 100076917(DECR1) 100078257(DECR2)
GGA: 100858408(DECR2) 420218(DECR1)
PCOC: 116227594(DECR1) 116230281(DECR2)
MGP: 100542270(DECR1) 100544413(DECR2)
CJO: 107310389(DECR1) 107320900(DECR2)
TPAI: 128079102(DECR2) 128090778(DECR1)
LMUT: 125690400(DECR1) 125700835(DECR2)
NMEL: 110394082(DECR1) 110405763(DECR2)
APLA: 101794432(DECR2) 101800525(DECR1)
ACYG: 106030535(DECR1) 106033348(DECR2)
CATA: 118247869(DECR1) 118249330(DECR2)
AFUL: 116486571(DECR1) 116495142(DECR2)
TGU: 100190086(DECR1) 100223602(DECR2)
LSR: 110477426(DECR1) 110482682(DECR2)
SCAN: 103813424(DECR1) 103817937(DECR2)
PMOA: 120495776(DECR1) 120512925(DECR2)
OTC: 121337048(DECR2) 121340147(DECR1)
PRUF: 121350660(DECR2) 121351931(DECR1)
GFR: 102031386(DECR1) 102041641(DECR2)
FAB: 101810228(DECR1) 101811791(DECR2)
OMA: 130250335(DECR1) 130259111(DECR2)
PHI: 102099571(DECR2) 102100338(DECR1)
PMAJ: 107199912(DECR1) 107211421(DECR2)
CCAE: 111924567(DECR1) 111936243(DECR2)
CCW: 104684942(DECR2) 104692760(DECR1)
CBRC: 103613444(DECR1) 103620502(DECR2)
ETL: 114061737(DECR1) 114067200(DECR2)
ZAB: 102065553(DECR1) 106630072(DECR2)
ACHL: 103806663(DECR2) 103810708(DECR1)
SVG: 106849865(DECR1) 106860589(DECR2)
MMEA: 130576425(DECR1) 130577233(DECR2)
HRT: 120752652(DECR1) 120759561(DECR2)
FPG: 101919053(DECR2) 101923272(DECR1)
FCH: 102049751(DECR2) 102056124(DECR1)
CLV: 102091063(DECR1) 102098896(DECR2)
EGZ: 104125807(DECR1) 104127269(DECR2)
NNI: 104016406(DECR1) 104023473(DECR2)
PCRI: 104023791(DECR1) 104024455(DECR2)
PLET: 104615075(DECR1) 104627605(DECR2)
EHS: 104504647(DECR2) 104512991(DECR1)
PCAO: 104049126(DECR2) 104053037(DECR1)
ACUN: 113476727(DECR1) 113485712(DECR2)
TALA: 104361179(DECR1) 104368635(DECR2)
PADL: 103912560(DECR2) 103917311(DECR1)
AFOR: 103895791(DECR1) 103898262(DECR2)
ACHC: 115335725(DECR2) 115340118(DECR1)
HALD: 104315750(DECR2) 104319085(DECR1)
HLE: 104828366(DECR1) 104831437(DECR2)
AGEN: 126034307 126046654
GCL: 127013452 127022476
CCRI: 104156295(DECR2) 104159659(DECR1)
CSTI: 104549248(DECR1) 104559386(DECR2)
CMAC: 104478852(DECR2) 104483410(DECR1)
MUI: 104537290(DECR2) 104548870(DECR1)
BREG: 104634918(DECR2) 104639054(DECR1)
FGA: 104078321(DECR1) 104081819(DECR2)
GSTE: 104257421(DECR1) 104263349(DECR2)
LDI: 104346271(DECR1) 104353132(DECR2)
MNB: 103771710(DECR2) 103773157(DECR1)
OHA: 104336091(DECR2) 104337579(DECR1)
NNT: 104399987(DECR1) 104408270(DECR2)
SHAB: 115604855(DECR1) 115606350(DECR2)
DPUB: 104297224(DECR1) 104300437(DECR2)
PGUU: 104458783(DECR1) 104466334(DECR2)
ACAR: 104518570(DECR1) 104522415(DECR2)
CPEA: 104393352(DECR2) 104396639(DECR1)
AVIT: 104273004(DECR1) 104281247(DECR2)
CVF: 104283754(DECR2) 104292468(DECR1)
RTD: 128905466(DECR1) 128913468(DECR2)
CUCA: 104056794(DECR1)
TEO: 104372463(DECR1) 104384134(DECR2)
BRHI: 104500372(DECR1)
AAM: 106496198(DECR1) 106500017(DECR2)
AROW: 112964076(DECR1) 112965875(DECR2)
NPD: 112955670(DECR2) 112960311(DECR1)
TGT: 104572495(DECR1) 104577897(DECR2)
DNE: 112983011(DECR1) 112986908(DECR2)
SCAM: 104143416(DECR2) 104143957(DECR1)
ASN: 102367904(DECR2) 102380885(DECR1)
AMJ: 102565758(DECR2) 102571942(DECR1)
CPOO: 109313424(DECR2) 109320262(DECR1)
GGN: 109287156(DECR2) 109305025(DECR1)
PSS: 102453305(DECR2)
CMY: 102929590(DECR1) 102939334(DECR2)
CCAY: 125632640(DECR1) 125643504(DECR2)
DCC: 119851809(DECR1) 119862482(DECR2)
CPIC: 101933439(DECR1) 101947023(DECR2)
TST: 117873644(DECR1) 117884008(DECR2)
CABI: 116833650(DECR1) 116836023(DECR2)
MRV: 120373171(DECR2) 120396998(DECR1)
ACS: 100561525(decr2) 100568104(decr1)
ASAO: 132774970(DECR1) 132781783(DECR2)
PVT: 110089491(DECR2) 110090231(DECR1)
SUND: 121914808(DECR2) 121929444(DECR1)
PBI: 103053170(DECR1) 103053628(DECR2)
PMUR: 107285746(DECR1) 107290316(DECR2)
CTIG: 120309460(DECR1) 120310929(DECR2)
TSR: 106540583(DECR2)
PGUT: 117668489(DECR1) 117673137(DECR2)
APRI: 131184968(DECR2) 131195838(DECR1)
PTEX: 113438681(DECR2) 113439922(DECR1)
NSS: 113420718(DECR2) 113428499(DECR1)
VKO: 123020321(DECR1) 123025212(DECR2)
PMUA: 114584421(DECR2) 114600444(DECR1)
PRAF: 128401602(DECR2) 128417271(DECR1)
ZVI: 118090362(DECR1) 118092971(DECR2)
HCG: 128323212(DECR1) 128336312(DECR2)
GJA: 107105991(DECR1) 107126196(DECR2)
STOW: 125431812(DECR2) 125439147(DECR1)
EMC: 129333745(DECR1) 129340590(DECR2)
XLA: 100137679(decr1.L) 443792(decr2.L)
XTR: 394884(decr2) 447965(decr1)
NPR: 108790945(DECR2) 108804496(DECR1)
RTEM: 120941285(DECR1) 120943319(DECR2)
BBUF: 121001490(DECR1) 121008465(DECR2)
BGAR: 122938690(DECR1) 122945128(DECR2)
MUO: 115475779(DECR2) 115478773(DECR1)
GSH: 117345749(DECR2) 117355210(DECR1)
DRE: 406623(decr2) 436717(decr1)
SRX: 107705494 107717880(decr2) 107756153
SANH: 107667207 107677236 107700707 107704989
SGH: 107556675(decr2) 107588511 107588514
CCAR: 109106610 109112190 109112195(decr2)
CAUA: 113042076 113042129 113059552 113092806
CGIB: 127945898 128012841 128030486
PTET: 122329639(decr2) 122359900(decr1) 122359931
LROH: 127156163(decr2) 127179096(decr1)
OMC: 131521233(decr1) 131533261(decr2)
PPRM: 120479779(decr2) 120484515(decr1)
RKG: 130103335(decr2) 130104393(decr1)
MAMB: 125243130(decr1) 125258505(decr2)
CIDE: 127497416 127506240
MASI: 127431580 127434138 127453399 127454002
TROS: 130547410(decr2) 130557638(decr1)
TDW: 130413596(decr2) 130433297(decr1)
MANU: 129425939(decr2) 129448361(decr1)
IPU: 108264653 108270672
IFU: 128605332(decr2) 128613264(decr1)
PHYP: 113526897(decr1) 113533695(decr2)
SMEO: 124384942(decr1) 124384948(decr2)
TFD: 113644660(decr1) 113663707(decr2)
TVC: 132845664(decr1) 132846446(decr2)
AMEX: 103033958 103034261(decr1) 111189707
CMAO: 118800365(decr1) 118822069(decr2)
EEE: 113572222(decr1) 113586569(decr2)
CHAR: 105896160(decr1) 105903306(decr2)
TRU: 101075792(decr2) 101076267(decr1)
TFS: 130525595(decr2) 130532124(decr1)
TNG: GSTEN00011542G001 GSTEN00024053G001
LCO: 104919685(decr2) 104937307(decr1)
NCC: 104946354(decr2)
TBEN: 117469470(decr1) 117473654(decr2)
CGOB: 115024610(decr2)
PGEO: 117442598(decr1) 117464823(decr2)
GACU: 117545098(decr2)
EMAC: 134863341(decr1) 134870385(decr2)
ELY: 117246739(decr2) 117265949(decr1)
EFO: 125881232(decr2) 125892961(decr1)
PLEP: 121937690(decr1) 121958915(decr2)
SLUC: 116044255(decr2) 116058490(decr1)
ECRA: 117937453(decr2) 117940578(decr1)
ESP: 116671808(decr2)
PFLV: 114548258(decr2) 114557403(decr1)
GAT: 120811158(decr1) 120819325(decr2)
PPUG: 119197560(decr1) 119212674(decr2)
AFB: 129091462(decr2) 129109646(decr1)
CLUM: 117745858(decr1) 117748672(decr2)
PSWI: 130203395(decr2) 130213178(decr1)
MSAM: 119884270 119892986 119916185(decr2)
SCHU: 122867584(decr2) 122881703(decr1)
CUD: 121514327(decr1) 121527972(decr2)
ALAT: 119006481(decr1) 119009419(decr2)
MZE: 101470346(decr2) 101484990(decr1)
ONL: 100699352(decr2) 100709209(decr1)
OAU: 116319921(decr2) 116334898(decr1)
OLA: 101162249(decr2) 101168931(decr1)
OML: 112139359(decr1) 112154585(decr2)
CSAI: 133418950(decr2) 133424892(decr1)
XMA: 102231692(decr2) 102237059(decr1)
XCO: 114140124(decr1) 114149662(decr2)
XHE: 116717891(decr1) 116726581(decr2)
PRET: 103477451(decr1) 103481087(decr2)
PFOR: 103131141(decr1) 103156078(decr2)
PLAI: 106940010(decr1) 106947556(decr2)
PMEI: 106929864(decr2) 106932705(decr1)
GAF: 122823501(decr2) 122830907(decr1)
PPRL: 129351017 129355851 129377621(decr2)
CVG: 107084994(decr2) 107095266(decr1)
CTUL: 119780902(decr1) 119793694(decr2)
GMU: 124865330(decr1) 124874740(decr2)
NFU: 107379237(decr1) 107388057(decr2)
KMR: 108228469(decr1) 108237227(decr2)
ALIM: 106517386(decr2) 106536744(decr1)
NWH: 119409589(decr1) 119423438(decr2)
AOCE: 111569477(decr1) 111579698(decr2)
MCEP: 125022146(decr2)
CSEM: 103381689(decr2) 103388041(decr1)
POV: 109623758 109626917(decr2) 109645468
SSEN: 122758843(decr2) 122774100(decr1)
HHIP: 117753122(decr2)
HSP: 118100587(decr2) 118113436(decr1)
SMAU: 118284560(decr1) 118287045(decr2)
LCF: 108884700 108886783
SDU: 111220127(decr2) 111234085(decr1)
SLAL: 111649954(decr1) 111658619(decr2)
XGL: 120784411(decr1) 120794747(decr2)
HCQ: 109512151(decr1) 109526513(decr2)
SSCV: 125974878 125991738
SBIA: 133495170(decr2) 133513674(decr1)
PEE: 133413226(decr1) 133417854(decr2)
PTAO: 133469230(decr2) 133487423(decr1)
BPEC: 110159721(decr2) 110172361(decr1)
MALB: 109963511(decr2) 109970890(decr1)
BSPL: 114842728(decr1) 114845733(decr2)
SJO: 128367051(decr1) 128381921(decr2)
SASA: 106580438 106605467(decr1)
STRU: 115159799(decr2) 115179715
OTW: 112222869 112223710(decr2)
OMY: 110486585(decr1) 110491617(decr2)
OGO: 123997805(decr1) 124047608(decr2)
ONE: 115103289 115106188(decr2) 115141000
OKI: 109865927(decr2) 109901961
OKE: 118364507(decr1) 118365921(decr2)
SALP: 111950544 111965036(decr1) 111978551(decr2)
SNH: 120031643 120045497(decr2) 120048458(decr1)
CCLU: 121567366(decr2) 121570301 121572412
ELS: 105019171(decr1) 105021269(decr2)
SFM: 108923861(decr2) 108940513(decr1)
PKI: 111841908(decr2) 111860660(decr1)
AANG: 118212784(decr1) 118217349(decr2)
LOC: 102687852(decr2) 102691826(decr1)
PSPA: 121301046(decr2) 121314994(decr1)
ARUT: 117431304(decr2) 117435439(decr1)
PSEX: 120515555(decr1) 120542275(decr2)
LCM: 102356436(DECR1) 102366665(DECR2)
CMK: 103178764(decr2) 103184930(decr1)
RTP: 109913573 109932331(decr2)
CPLA: 122549009(decr1) 122560650(decr2)
HOC: 132815458(decr1) 132825186(decr2)
LERI: 129696131(decr1) 129706880(decr2)
PMRN: 116949615(DECR2) 116954238(DECR1)
LRJ: 133346952(DECR2) 133347304 133355761 133355984
BFO: 118417612 118429724
BBEL: 109462821 109473564
CIN: 100180648 100185689
SCLV: 120326758 120342156 120343108
SPU: 588523 589146 590477 763456
LPIC: 129254267 129254268 129269192 129269917 129280007
APLC: 110980338 110980385 110980398 110982170
AJC: 117110195 117123054
SKO: 100368583 100379042
BCOO: 119066676
FCD: 110843971 110853998
DPX: DAPPUDRAFT_305017
DMK: 116917892
DPZ: 124315024
PVM: 113816958
PJA: 122257636
PCHN: 125041762
PMOO: 119581889
HAME: 121863235
PCLA: 123775311
CQD: 128705316
PTRU: 123511463
ESN: 126980956
MNZ: 135217285
HAZT: 108674833
EAF: 111706449
TCF: 131885367
PPOI: 119099366
DSV: 119444718 119445674
RSAN: 119390804 119390810
RMP: 119170719 119182208
VDE: 111247167
VJA: 111273806
CSCU: 111633074
LPOL: 106474967
CEL: CELE_F53C11.3(decr-1.1) CELE_T05C12.3(decr-1.3) CELE_W01C9.4(decr-1.2)
CBR: CBG_00572(Cbr-decr-1.3) CBG_11484
CRQ: GCK72_004945
NAI: NECAME_10436
HRO: HELRODRAFT_187537
LGI: LOTGIDRAFT_213936 LOTGIDRAFT_229651
PVUL: 126811702 126816103
PCAN: 112563050 112576860
BGT: 106053809 106063822
GAE: 121379840 121388688
HRF: 124132560 124137563
HRJ: 124279566 124284549
CRG: 105324316 105342001
CVN: 111122122 111134852
CANU: 128164683 128186955
OED: 125668442 125680859
MYI: 110441650 110448587 110448641
PMAX: 117332856 117337164
MCAF: 127700912 127707736
MMER: 123548816 123565071
RPHI: 132737925 132750410
DPOL: 127844933 127865755
OBI: 106873880 106883385
OSN: 115214067 115221495
LAK: 106155259 106176835
OVI: T265_01692
NVE: 5499755 5502416 5504216 5506878
EPA: 110232461 110237641
ATEN: 116297860 116302373
ADF: 107332695 107336221 107352209
AMIL: 114958158 114968880
PDAM: 113673646 113685316
SPIS: 111336265
DGT: 114517200
XEN: 124436555
HMG: 100208057
HSY: 130614052
TAD: TRIADDRAFT_31628 TRIADDRAFT_63390
AQU: 100636990 100641010
ATH: AT2G07640 AT3G12800(SDRB)
ALY: 9320993
CRB: 17890996
CSAT: 104745501 104765047 104772309 104777002
EUS: EUTSA_v10021233mg
BRP: 103859468 103870224
BNA: 106353105 106389842 106400716 106452364
BOE: 106328417 106343258
RSZ: 108856424 108856608 130495182
THJ: 104826329
CPAP: 110817285 110817384
CIT: 102615558 102627054
CIC: CICLE_v10005524mg CICLE_v10016100mg
PVY: 116137055
MINC: 123197975
TCC: 18594888 18607039
GRA: 105763066 105766230 105792781
GHI: 107909155 107928399 107928733 107945225 107947876
GAB: 108452465 108467898 108478611
HSYR: 120143813 120144485 120161509 120174092 120197919
DZI: 111283033 111287924 111308529
EGR: 104440625 104451030 120292907
GMX: 100793630 100800885
GSJ: 114388153 114422642
PVU: PHAVU_008G1453000
VRA: 106755217
VAR: 108319077
VUN: 114170705
VUM: 124820565
CCAJ: 109791092
APRC: 113864488
MTR: 25502359
TPRA: 123896675 123896677 123896743 123896744
CAM: 101506957 101507712
PSAT: 127075440 127075441
VVO: 131620305
LJA: Lj0g3v0286659.1(Lj0g3v0286659.1) Lj0g3v0286659.2(Lj0g3v0286659.2)
ADU: 107478393
AIP: 107630070
AHF: 112737912 112790048
LANG: 109339361
PCIN: 129297276 129301388 129315832
QSA: O6P43_001229 O6P43_029379
FVE: 101293375 101306851
RCN: 112164582 112202202
PPER: 18778155 18778633
PMUM: 103325473 103325732
PAVI: 110746351 110747664 110767357
PDUL: 117624062 117626717
MDM: 103435295 103435392 103445870
MSYL: 126586374 126622182 126624572
PXB: 103933731
ZJU: 107417910 107420848
MNT: 112091285
CSAV: 115709085 115710052
CSV: 101215029
CMO: 103489636
BHJ: 120078067
MCHA: 111016706
CMAX: 111468426
CMOS: 111455238
CPEP: 111776381
RCU: 8260156 8289500
JCU: 105641060 105646164
HBR: 110665963
MESC: 110599864 110608081
POP: 7479623 7482193
PEU: 105129532 105136866
PALZ: 118052952 118060618
JRE: 108984959 109011254
CILL: 122279668 122281108
CAVE: 132170819 132171552 132175934
QSU: 112007613 112035780
QLO: 115987299
TWL: 119987620
VVI: 100248493 100257583
VRI: 117909399 117914133
SLY: 101254404
SPEN: 107025337
SOT: 102605057
SSTN: 125875879
SDUL: 129891657
CANN: 107878931
LBB: 132618419
NTA: 107763475 107782910 107800988
NSY: 104219422
NTO: 104087848 104087849
NAU: 109234111
INI: 109178098
ITR: 116019133
SIND: 105168104 105175095
OEU: 111368230 111395865
EGT: 105962147 105968604
SSPL: 121745555 121755463 121758659 121786331 121791066
SMIL: 130986006 131011412
SHIS: 125187272 125193671 125216932
APAN: 127249608 127253317
HAN: 110895870 110929812 110929814
ECAD: 122580558 122600999
LSV: 111908954 111911099
CCAV: 112499806 112512023
DCR: 108206087 108224824
CSIN: 114261588 114278254
RVL: 131321831
AEW: 130792575
BVG: 104887053
SOE: 110804428
CQI: 110707556 110739385
ATRI: 130803889
MOF: 131143779 131160595
NNU: 104599664
MING: 122090015
TSS: 122640147 122640148
PSOM: 113287325 113295327 113313499 113323261 113323272 113335451 113342600
OSA: 4336980
DOSA: Os04t0614000-01(Os04g0614000)
OBR: 102701258
OGL: 127771165
BDI: 100838861
ATS: 109766461
TDC: 119356202 119365360
TAES: 123046447 123054286 123190182
TUA: 125539479
LPER: 127336200
LRD: 124673887 124673888 124674029 124674030
SBI: 8063963 8063964
ZMA: 100194355 103504713
SITA: 101779665 101780066
SVS: 117864079 117864080
PVIR: 120641762 120641763 120682056 120682057
PHAI: 112898815 112898817
PDA: 103713168
EGU: 105059878 105059879
MUS: 103969191 103979005
ZOF: 122009986 122016985
DCT: 110096616 110103734 110116176
PEQ: 110022199 110028721
AOF: 109822210 109845167
MSIN: 131221031
NCOL: 116244776 116251308
ATR: 18421380
SMO: SELMODRAFT_146763 SELMODRAFT_178329 SELMODRAFT_271745 SELMODRAFT_57313
PPP: 112272949 112276038
CRE: CHLRE_17g731850v5
VCN: VOLCADRAFT_67136
MNG: MNEG_7336
CSL: COCSUDRAFT_19871
CVR: CHLNCDRAFT_136871
APRO: F751_1204
SCE: YNL202W(SPS19)
SEUB: DI49_4540
SPAO: SPAR_N01210
AGO: AGOS_ABL163W
ERC: Ecym_6446
KLA: KLLA0_D18909g
KMX: KLMA_50587(SPS19)
LTH: KLTH0B07656g
VPO: Kpol_1054p31
ZRO: ZYRO0C10274g
CGR: CAGL0H08063g
NCS: NCAS_0G01600(NCAS0G01600)
NDI: NDAI_0F03580(NDAI0F03580)
TPF: TPHA_0O01750(TPHA0O01750)
TBL: TBLA_0B00350(TBLA0B00350)
TGB: HG536_0D00640
TDL: TDEL_0A00890(TDEL0A00890)
KAF: KAFR_0A07740(KAFR0A07740)
KNG: KNAG_0F01080(KNAG0F01080)
ZMK: HG535_0G01180
PPA: PAS_chr3_0975
DHA: DEHA2C02178g DEHA2G22198g
PIC: PICST_45705 PICST_57591
PGU: PGUG_00071 PGUG_01155
SPAA: SPAPADRAFT_141696 SPAPADRAFT_57939
LEL: PVL30_001606(SPS19_1) PVL30_003969(SPS19_2)
CAL: CAALFM_C102270CA(CaO19.3684) CAALFM_C400830WA(SPS20)
CTP: CTRG_00064 CTRG_04642
COT: CORT_0B07500 CORT_0E01150
CDU: CD36_02120 CD36_40880
CTEN: CANTEDRAFT_116941 CANTEDRAFT_97280
YLI: YALI0C03003g YALI0D01694g YALI0E14322g
CLU: CLUG_01714 CLUG_03177
CLUS: A9F13_12g02167 A9F13_13g01595
CAUR: CJI96_0002629 CJI96_0003150
SLB: AWJ20_246(SPS19) AWJ20_4294(SPS19)
PKZ: C5L36_0A11080
BNN: FOA43_003564
BBRX: BRETT_004426
OPA: HPODL_02860
NCR: NCU07958
NTE: NEUTE1DRAFT120724(NEUTE1DRAFT_120724)
SMP: SMAC_08571
PAN: PODANSg451
PBEL: QC761_301660(SPS19)
PPSD: QC762_301660(SPS19)
PPSP: QC763_301660(SPS19)
PPSA: QC764_301660(SPS19)
TTT: THITE_2115925
MTM: MYCTH_2299438
CTHR: CTHT_0030520
MGR: MGG_05138
PPEI: PpBr36_03509
PGRI: PgNI_09625
TMN: UCRPA7_1275
SSCK: SPSK_02618
FGR: FGSG_00407
FPU: FPSE_00069
FPOA: FPOAC1_000427
FVN: FVRRES_00571
FVR: FVEG_00866
FOX: FOXG_00645
NHE: NECHADRAFT_98848
FFC: NCS54_00110400 NCS54_01361200
FKR: NCS57_00108500
FMU: J7337_001127
TRE: TRIREDRAFT_76114
TRR: M419DRAFT_95960
MAW: MAC_03197
MAJ: MAA_04291
PCHM: VFPPC_15099
CMT: CCM_02294
AMUS: LMH87_003916
PLJ: VFPFJ_05170
PTKZ: JDV02_001298(SPS19)
VAL: VDBG_06030
VDA: VDAG_03191
CHIG: CH63R_05266 CH63R_11784
SAPO: SAPIO_CDS3090
ELA: UCREL1_8151
PFY: PFICI_00825
SSL: SS1G_04630
BFU: BCIN_01g07920
MBE: MBM_09949
PSCO: LY89DRAFT_636319
GLZ: GLAREA_11191
ANI: ANIA_07770
AFM: AFUA_5G07470
ACT: ACLA_010730
NFI: NFIA_079800
AOR: AO090701000656
ANG: An15g02860
AFV: AFLA_005173
ALUC: AKAW2_60416A
ACHE: ACHE_21289S
APUU: APUU_71179S APUU_80095A
PCS: N7525_004871
PDP: PDIP_52890
POU: POX_a00313
TMF: EYB26_002233
TRG: TRUGW13939_08192
CIM: CIMG_06119
CPW: CPC735_026800
URE: UREG_04269
PBL: PAAG_04894
PBN: PADG_02632
ABE: ARB_04033
TVE: TRV_05037
AJE: HCAG_02897
BGH: BDBG_04122
PNO: SNOG_16378(SNOG_16377)
PTE: PTT_16264
BZE: COCCADRAFT_851
BSC: COCSADRAFT_37351
BOR: COCMIDRAFT_41422
AALT: CC77DRAFT_1015750
ARAB: EKO05_0011339
ZTR: MYCGRDRAFT_69507
PFJ: MYCFIDRAFT_163004
FFU: CLAFUR5_06466
CBET: CB0940_08322
BCOM: BAUCODRAFT_392081
NPA: UCRNP2_6972
TML: GSTUM_00004837001
CNE: CNI03790
CNB: CNBH3620
CNG: CNAG_04238
CGI: CGB_H4250C
CDEU: CNBG_2808
TMS: TREMEDRAFT_70655
TASA: A1Q1_00949
CCAC: CcaHIS019_0702800(SPS19)
PPL: POSPLDRAFT_86906
TVS: TRAVEDRAFT_160280
DSQ: DICSQDRAFT_110031
PCO: PHACADRAFT_246120
SHS: STEHIDRAFT_164262
HIR: HETIRDRAFT_127365
PSQ: PUNSTDRAFT_117041
ADL: AURDEDRAFT_112734
FME: FOMMEDRAFT_122494
GTR: GLOTRDRAFT_69683
RSX: RhiXN_03664
LBC: LACBIDRAFT_251259(SPS)
CCI: CC1G_05835
ABP: AGABI1DRAFT115110(AGABI1DRAFT_115110)
ABV: AGABI2DRAFT196138(AGABI2DRAFT_196138)
PCUB: JR316_0011337
MPR: MPER_08115
MRR: Moror_8639
MORE: E1B28_006077
SCM: SCHCO_02641597(SCHCODRAFT_02641597)
CPUT: CONPUDRAFT_111684
SLA: SERLADRAFT_471035
WSE: WALSEDRAFT_37173
WIC: J056_001683
UMA: UMAG_10183
PFP: PFL1_01922
SGRA: EX895_004542
MGL: MGL_1622
MRT: MRET_0717
MSYM: MSY001_2513
PGR: PGTG_13490
PTRC: PtA15_6A358
PSTR: Pst134EA_003059
MLR: MELLADRAFT_41456
ACAN: ACA1_288870
TGO: TGME49_226300
TET: TTHERM_00637450
PTM: GSPATT00022482001 GSPATT00036343001
PTI: PHATRDRAFT_11319(DER1)
FCY: FRACYDRAFT_212175
TPS: THAPSDRAFT_35810
AAF: AURANDRAFT_58778
PIF: PITG_13341 PITG_15640
PSOJ: PHYSODRAFT_286541 PHYSODRAFT_502845
SPAR: SPRG_02815
NGR: NAEGRDRAFT_31570
MSTO: MSTO_20200
 » show all
Reference
1  [PMID:729581]
  Authors
Kunau WH, Dommes P.
  Title
Degradation of unsaturated fatty acids. Identification of intermediates in the degradation of cis-4-decenoly-CoA by extracts of beef-liver mitochondria.
  Journal
Eur J Biochem 91:533-44 (1978)
DOI:10.1111/j.1432-1033.1978.tb12707.x
Reference
2  [PMID:6749495]
  Authors
Dommes V, Luster W, Cvetanovic M, Kunau WH.
  Title
Purification by affinity chromatography of 2,4-dienoyl-CoA reductases from bovine liver and Escherichia coli.
  Journal
Eur J Biochem 125:335-41 (1982)
DOI:10.1111/j.1432-1033.1982.tb06688.x
Reference
3  [PMID:9268358]
  Authors
Gurvitz A, Rottensteiner H, Kilpelainen SH, Hartig A, Hiltunen JK, Binder M, Dawes IW, Hamilton B
  Title
The Saccharomyces cerevisiae peroxisomal 2,4-dienoyl-CoA reductase is encoded by the oleate-inducible gene SPS19.
  Journal
J Biol Chem 272:22140-7 (1997)
DOI:10.1074/jbc.272.35.22140
  Sequence
[hsa:1666] [rno:117543] [sce:YNL202W]
Reference
4  [PMID:10464321]
  Authors
Geisbrecht BV, Liang X, Morrell JC, Schulz H, Gould SJ
  Title
The mouse gene PDCR encodes a peroxisomal delta(2), delta(4)-dienoyl-CoA reductase.
  Journal
J Biol Chem 274:25814-20 (1999)
DOI:10.1074/jbc.274.36.25814
  Sequence
[mmu:26378]
Reference
5  [PMID:11514237]
  Authors
De Nys K, Meyhi E, Mannaerts GP, Fransen M, Van Veldhoven PP
  Title
Characterisation of human peroxisomal 2,4-dienoyl-CoA reductase.
  Journal
Biochim Biophys Acta 1533:66-72 (2001)
DOI:10.1016/s1388-1981(01)00141-x
  Sequence
[hsa:26063]
Reference
6  [PMID:15531764]
  Authors
Alphey MS, Yu W, Byres E, Li D, Hunter WN
  Title
Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase: enzyme-ligand interactions in a distinctive short-chain reductase active site.
  Journal
J Biol Chem 280:3068-77 (2005)
DOI:10.1074/jbc.M411069200
  Sequence
[hsa:1666]
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.124
IUBMB Enzyme Nomenclature: 1.3.1.124
ExPASy - ENZYME nomenclature database: 1.3.1.124
BRENDA, the Enzyme Database: 1.3.1.124

  All links  
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG REACTION (2)   
Gene (2037)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (1398)   
   KEGG MGENES (637)   
Protein sequence (4906)   
   UniProt (4872)   
   SWISS-PROT (12)   
   RefSeq(pep) (22)   
DNA sequence (25)   
   RefSeq(nuc) (24)   
   EMBL (1)   
Protein domain (3)   
   InterPro (3)   
All databases (6979)   

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