KEGG   ENZYME: 1.3.1.125
Entry
EC 1.3.1.125                Enzyme                                 
Name
acrylate reductase;
ard (gene name);
NADH:acrylate oxidoreductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
propanoate:NAD+ oxidoreductase
Reaction(IUBMB)
propanoate + NAD+ = acrylate + NADH + H+ [RN:R13136]
Reaction(KEGG)
R13136
Substrate
propanoate [CPD:C00163];
NAD+ [CPD:C00003]
Product
acrylate [CPD:C00511];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme, characterized from the marine bacterium Vibrio harveyi, enables the organism to utilize acrylate as the terminal electron acceptor for NADH regeneration under anaerobic conditions.
History
EC 1.3.1.125 created 2022
Pathway
ec00640  Propanoate metabolism
ec01100  Metabolic pathways
Orthology
K26355  acrylate reductase
Genes
PROD: PCO85_04695
VHA: VIBHAR_05539
VCA: M892_23855
VHR: AL538_25370
VOW: A9237_19860
VGA: BSQ33_15260
VSH: BSZ05_19580
VAF: D1115_19610
VSR: Vspart_01386(urdA_1)
EEI: NX720_05785
ENG: O2T12_21310 O2T12_23370
CDIZ: CEDIAZO_01025(namA_1)
SER: SERP2381
SEP: SE_0195
SEPP: SEB_00124
SEPS: DP17_1268
SLG: SLGD_00224
SLN: SLUG_02230
SSIF: AL483_10675
GEQ: CG018_00505
PTA: HPL003_01965
PMAE: LMZ02_07280
SUB: SUB1360
STK: STP_1198
SCF: Spaf_0869
SPAT: A0O21_07075
SCHJ: DDV21_008990
SPOC: NCTC10925_00464
SOS: INT76_00535
ECAS: ECBG_02589
EGA: AL523_01535
EGV: EGCR1_08750
ERAF: J9537_10830
SMOE: RGT18_09240
 » show all
Reference
1  [PMID:35612301]
  Authors
Bertsova YV, Serebryakova MV, Baykov AA, Bogachev AV.
  Title
A Novel, NADH-Dependent Acrylate Reductase in Vibrio harveyi.
  Journal
Appl Environ Microbiol 88:e0051922 (2022)
DOI:10.1128/aem.00519-22
  Sequence
[vhr:AL538_25370]
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.125
IUBMB Enzyme Nomenclature: 1.3.1.125
ExPASy - ENZYME nomenclature database: 1.3.1.125
BRENDA, the Enzyme Database: 1.3.1.125

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Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (1)   
   KEGG REACTION (1)   
Gene (80)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (35)   
   KEGG MGENES (44)   
All databases (90)   

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