| Entry |
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| Name |
geissoschizine dehydrogenase
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| Class |
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
geissoschizine:NADP+ 4,21-oxidoreductase
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| Reaction(IUBMB) |
geissoschizine + NADP+ = 4,21-didehydrogeissoschizine + NADPH [RN: R03860]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
4,21-didehydrogeissoschizine;
NADPH [CPD: C00005]
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| Comment |
Involved in the interconversion of heteroyohimbine alkaloids in Catharanthus roseus.
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| History |
EC 1.3.1.36 created 1986
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| Pathway |
| ec00901 | Indole alkaloid biosynthesis |
| ec01110 | Biosynthesis of secondary metabolites |
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| Orthology |
| K23493 | geissoschizine synthase |
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| Reference |
1 |
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| Authors |
Pfitzner, A. and Stockigt, J. |
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| Title |
Partial-purification and characterization of geissoschizine dehydrogenase from suspension-cultures of Catharanthus roseus. |
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| Journal |
Phytochemistry 21:1585-1588 (1982) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 1.3.1.36 |
| ExPASy - ENZYME nomenclature database: | 1.3.1.36 |
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