Entry
Name
cis-2-enoyl-CoA reductase (NADPH);
NADPH-dependent cis-enoyl-CoA reductase;
reductase, cis-2-enoyl coenzyme A;
cis-2-enoyl-coenzyme A reductase;
cis-2-enoyl-CoA reductase (NADPH)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
acyl-CoA:NADP+ cis-2-oxidoreductase
Reaction(IUBMB)
acyl-CoA + NADP+ = cis-2,3-dehydroacyl-CoA + NADPH + H+ [RN:
R00387 ]
Reaction(KEGG)
Substrate
Product
Comment
Not identical with EC
1.3.1.38 trans-2-enoyl-CoA reductase (NADPH) [cf. EC
1.3.1.8 acyl-CoA dehydrogenase (NADP+)].
History
EC 1.3.1.37 created 1986
Reference
Authors
Mizugaki M, Nishimaki T, Shiraishi T, Kawaguchi A, Okuda S, Yamanaka H.
Title
Studies on the metabolism of unsaturated fatty acids. IX. Stereochemical studies of the reaction catalyzed by trans-2-enoyl-coenzyme A reductase of Escherichia coli.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.37
ExPASy - ENZYME nomenclature database: 1.3.1.37