Entry |
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Name |
cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase
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Class |
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
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Sysname |
cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate:NAD(P)+ oxidoreductase (decarboxylating)
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Reaction(IUBMB) |
cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NAD(P)+ = 4-methylcatechol + NAD(P)H + CO2 [RN: R05292 R05293]
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Reaction(KEGG) |
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Substrate |
cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate [CPD: C06729];
NAD+ [CPD: C00003];
NADP+ [CPD: C00006]
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Product |
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Comment |
Involved in the p-xylene degradation pathway in bacteria.
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History |
EC 1.3.1.67 created 2000
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Pathway |
ec01120 | Microbial metabolism in diverse environments |
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Reference |
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Authors |
Whited GM, McCombie WR, Kwart LD, Gibson DT. |
Title |
Identification of cis-diols as intermediates in the oxidation of aromatic acids by a strain of Pseudomonas putida that contains a TOL plasmid. |
Journal |
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Other DBs |
ExplorEnz - The Enzyme Database: | 1.3.1.67 |
ExPASy - ENZYME nomenclature database: | 1.3.1.67 |
UM-BBD (Biocatalysis/Biodegradation Database): | 1.3.1.67 |
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