KEGG   ENZYME: 1.3.1.97
Entry
EC 1.3.1.97                 Enzyme                                 
Name
botryococcene synthase;
SSL-3 (gene name)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
C30 botryococcene:NADP+ oxidoreductase
Reaction(IUBMB)
C30 botryococcene + NADP+ + diphosphate = presqualene diphosphate + NADPH + H+ [RN:R10194]
Reaction(KEGG)
R10194
Substrate
C30 botryococcene [CPD:C20432];
NADP+ [CPD:C00006];
diphosphate [CPD:C00013]
Product
presqualene diphosphate [CPD:C03428];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Isolated from the green alga Botryococcus braunii BOT22. Acts in the reverse direction. Involved in the production of botryococcenes, which are triterpenoid hydrocarbons of isoprenoid origin produced in large amount by this alga.
History
EC 1.3.1.97 created 2012
Orthology
K21150  botryococcene synthase
Reference
1  [PMID:21746901]
  Authors
Niehaus TD, Okada S, Devarenne TP, Watt DS, Sviripa V, Chappell J
  Title
Identification of unique mechanisms for triterpene biosynthesis in Botryococcus braunii.
  Journal
Proc Natl Acad Sci U S A 108:12260-5 (2011)
DOI:10.1073/pnas.1106222108
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.97
IUBMB Enzyme Nomenclature: 1.3.1.97
ExPASy - ENZYME nomenclature database: 1.3.1.97
BRENDA, the Enzyme Database: 1.3.1.97

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