KEGG ENZYME: 1.3.7.11

ENZYME: 1.3.7.11

Entry

EC 1.3.7.11                 Enzyme

Name

2,3-bis-O-geranylgeranyl-sn-glycero-phospholipid reductase;
AF0464 (gene name);
2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase (donor)

Class

Oxidoreductases;
Acting on the CH-CH group of donors;
With an iron-sulfur protein as acceptor

Sysname

2,3-bis-(O-phytanyl)-sn-glycero-phospholipid:ferredoxin oxidoreductase

Reaction(IUBMB)

a 2,3-bis-(O-phytanyl)-sn-glycero-phospholipid + 16 oxidized ferredoxin [iron-sulfur] cluster = a 2,3-bis-(O-geranylgeranyl)-sn-glycero-phospholipid + 16 reduced ferredoxin [iron-sulfur] cluster + 16 H+

Reaction(KEGG)

(other) R10331

Substrate

2,3-bis-(O-phytanyl)-sn-glycero-phospholipid [CPD:C22634];
oxidized ferredoxin [iron-sulfur] cluster [CPD:C00139]

Product

2,3-bis-(O-geranylgeranyl)-sn-glycero-phospholipid;
reduced ferredoxin [iron-sulfur] cluster [CPD:C00138];
H+ [CPD:C00080]

Comment

A flavoprotein (FAD). The enzyme is involved in the biosynthesis of archaeal membrane lipids. It catalyses the reduction of all 8 double bonds in 2,3-bis-O-geranylgeranyl-sn-glycero-phospholipids and all 4 double bonds in 3-O-geranylgeranyl-sn-glycerol phospholipids with comparable activity. Unlike EC 1.3.1.101, 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H], this enzyme shows no activity with NADPH, and requires a dedicated ferredoxin [4].

History

EC 1.3.7.11 created 2013 as EC 1.3.99.34, transferred 2015 to EC 1.3.7.11

Pathway

ec00564

Glycerophospholipid metabolism

ec01110

Biosynthesis of secondary metabolites

Orthology

K17830

digeranylgeranylglycerophospholipid reductase

Genes

PMEX:

H4W19_05940

PDD:	MNQ95_14045

LAB:	LA76x_2426

LAQ:	GLA29479_2709

LGU:	LG3211_2789

LEZ:

GLE_2795

LEM:

LEN_2236

LMB:	C9I47_1426

LYT:	DWG18_07380

LYJ:	FKV23_07190

LSX:	H8B22_00975

LHX:	LYSHEL_30720

LCAS:

LYSCAS_30690

THES:

FHQ07_02060

TBV:	H9L17_15740

HHC:	M911_11185

EBS:	ECTOBSL9_0276

TGR:

Tgr7_2205

TKM:

TK90_0643

TVR:

TVD_10595

APRS:

BI364_13760

SVA:

SVA_2992

ACII:

C4901_12925

ATY:	A9R16_004045

CGD:	CR3_0650(fixC)

VPE:	Varpa_3679

VBO:	CKY39_19940

VAM:	C4F17_03155

SDR:	SCD_n00804

SULF:

CAP31_01895

SPLB:

SFPGR_29360

SNIV:

SFSGTM_27200

URU:	DSM104443_00527

BEBA:

BWI17_02380

HDN:

Hden_0684

RVA:

Rvan_3542

FIL:	BN1229_v1_0189

FIY:	BN1229_v1_0193

CMAR:

IMCC12053_1371

RHC:

RGUI_1289

AMYL:

QBD29_00465

AFR:

AFE_2544

AFE:	Lferr_2172

ACU:

Atc_2341

ACZ:	Acaty_c2184

AFI:	Acife_2465

AFJ:	AFERRID_05040

AFP:	K1Y48_09080

DOL:

Dole_0399

DTI:	Desti_0238

DBR:

Deba_3038

CBK:	CLL_A1369 CLL_A1370

CLB:	Clo1100_3094 Clo1100_3095

CLT:	CM240_1758 CM240_1759

HSC:

HVS_14075

CCE:	Ccel_1057 Ccel_1058

RHER:

EHE19_004620 EHE19_004625

RPAY:

P0092_17605

SALQ:

SYNTR_0780

DOR:	Desor_4339

PTH:	PTH_0378(FixC)

DKU:	Desku_2287

FWA:	DCMF_14630

DGI:	Desgi_1545

TEX:	Teth514_0218 Teth514_0219

THX:	Thet_0258 Thet_0259

TPD:	Teth39_1995

TIT:	Thit_0239 Thit_0240

TMT:	Tmath_0322 Tmath_0323

TBO:	Thebr_2044

TWI:	Thewi_0279

TKI:	TKV_c02330

TPZ:	Tph_c09910(bchP)

TXY:	Thexy_2059

TSH:

Tsac_0175

TEP:	TepRe1_0379

TAE:	TepiRe1_0421

BACG:

D2962_14315

TOC:

Toce_0251

NTH:	Nther_1774

KME:	H0A61_01699

STED:

SPTER_30020(kmo)

CALK:

HUE98_00670

BALA:

DSM104299_03518

PARN:

NBH00_13915

PBAJ:

LRS13_19280

PMT:

PMT_0686

PMF:	P9303_15361

PMJ:	P9211_08531

CSN:	Cyast_1222

MAR:

MAE_31260

MPK:

VL20_5387

MIQ:	B5D77_03105

MVZ:	myaer102_06730

CYC:	PCC7424_4688

CYJ:	Cyan7822_4141

PAGH:

NIES204_25480

PPSU:

NO713_00666

OXY:	HCG48_06915

MVAG:

D0A34_03765

OAC:	Oscil6304_0659

ONI:	Osc7112_3504

MIC:	Mic7113_1946

GEI:	GEI7407_1050

PLP:	Ple7327_4278

ABAT:

CFX1CAM_1448

KBS:	EPA93_17655

KBB:	ccbrp13_22200

PNL:

PNK_0017

PND:	Pla175_09780

FSU:	Fisuc_0330 Fisuc_2122

FSC:	FSU_0745 FSU_2657

POM:	MED152_04120

POB:	LPB03_12595 LPB03_16045

PRN:	BW723_10930

POLA:

BXQ17_11625

POA:	CW731_11625

PLIT:

K8354_10745

PBAT:

JL193_08020

PCEA:

J3359_02050

IAL:

IALB_0329

HYA:	HY04AAS1_0807

HHO:	HydHO_0802

HYS:	HydSN_0819

TAL:

Thal_0865

TRD:	THERU_04165

KPF:	IX53_05590

CPO:	COPRO5265_1158

CABY:

Cabys_957

DTH:	DICTH_0710

DTU:

Dtur_0864

BANA:

BARAN1_0630

BIH:	BIP78_0559

MJA:

MJ_0532

MFE:	Mefer_0023 Mefer_0586

MVU:	Metvu_0248 Metvu_0470

MFS:	MFS40622_0302 MFS40622_0533

MIF:	Metin_0313

MJH:	JH146_0202

MESG:

MLAUSG7_0668

MESA:

MLASG1_0156

MIG:	Metig_0018

MMP:

MMP0388

MMQ:	MmarC5_1250

MMX:	MmarC6_0522

MMZ:	MmarC7_1386

MMD:

GYY_02010

MMAK:

MMKA1_04070

MMAO:

MMOS7_04030

MMAD:

MMJJ_06490

MAE:

Maeo_1307

MVN:	Mevan_1375

MVO:

Mvol_1689

MOK:	Metok_0574

METF:

CFE53_00320

MTH:	MTH_1718 MTH_277

MMG:	MTBMA_c02950 MTBMA_c07260 MTBMA_c11210

MWO:	MWSIV6_0259 MWSIV6_0692 MWSIV6_1100

MTEE:

MTTB_09190 MTTB_14720

METC:

MTCT_0239 MTCT_1570

METE:

tca_00257(menJ_1) tca_01663(menJ_2)

METZ:

METMT2_0572 METMT2_0721 METMT2_1561

METK:

FVF72_00920 FVF72_03085

MTHM:

FZP57_01175 FZP57_03320 FZP57_05215

METJ:

FZP68_06180 FZP68_08325

MST:	Msp_0758 Msp_0874 Msp_1062 Msp_1307 Msp_1320

METB:

AW729_08940 AW729_09050 AW729_10575 AW729_10930

MEIS:

PXD04_00860 PXD04_02310 PXD04_02685

MRU:	mru_1341 mru_1441 mru_1471

MSI:

Msm_1701

MEB:	Abm4_0728 Abm4_1169

MMIL:

sm9_1381

MEYE:

TL18_04135

MOL:	YLM1_0823 YLM1_0971

MARO:

MarbSA_00110

METV:

K4897_00040

MEL:	Metbo_0471 Metbo_2033 Metbo_2366

MEW:	MSWAN_0290 MSWAN_0605 MSWAN_1925

METH:

MBMB1_0335 MBMB1_0639 MBMB1_1556 MBMB1_1827

MFC:	BRM9_0792 BRM9_1599 BRM9_1933 BRM9_2158

MFI:	DSM1535_0120 DSM1535_0754 DSM1535_1097 DSM1535_2293

MCUB:

MCBB_0308 MCBB_0619 MCBB_1812

MSUB:

BK009_01280 BK009_06770 BK009_11855

METN:

BK008_02415 BK008_07495 BK008_09685

METT:

CIT01_01350 CIT01_04015 CIT01_04025 CIT01_07320 CIT01_10150

METO:

CIT02_03745 CIT02_05170 CIT02_08440 CIT02_10165

MEME:

HYG87_07945 HYG87_10880

MFEG:

GCM10025860_04480 GCM10025860_12360 GCM10025860_16550

MFV:	Mfer_0516 Mfer_1222

MKA:	MK1443 MK1645

AFU:

AF_0464

AFG:	AFULGI_00004710

APO:	Arcpr_0713

AVE:	Arcve_2050

AST:	Asulf_00147 Asulf_01626

FPL:	Ferp_0366 Ferp_1444

GAC:	GACE_0072 GACE_0595

GAH:	GAH_00300 GAH_00353 GAH_01689

PFU:

PF0097

PFI:

PFC_07720

PHO:	PH0181(PH0181)

PAB:	PAB0109(bchP)

PYN:

PNA2_0702

PYA:	PYCH_16330

PYS:

Py04_0252

PYC:	TQ32_00315

TKO:

TK1088

TON:

TON_0316

TGA:

TGAM_1305

TSI:

TSIB_0988

TBA:	TERMP_00654

THE:

GQS_03690

THA:

TAM4_1982

THM:

CL1_0388

TLT:

OCC_08470

THS:

TES1_0613

TNU:

BD01_0182

TEU:

TEU_06540

TGY:	X802_10265

THV:	ADU37_CDS08620

TCH:	CHITON_0316

TPEP:

A0127_09785

TPIE:

A7C91_07555

TGG:	A3K92_03945

TCE:	A3L02_00260

TBS:	A3L01_02245

THH:	CDI07_02200

TSL:	A3L11_06065

TTD:	A3L14_03705

TPRF:

A3L09_05905

TRL:	A3L10_04285

TPAF:

A3L08_04750

THY:	A3L12_01970

TIC:	FH039_04700

TCQ:	TIRI35C_0673

THEM:

FPV09_04700

THEI:

K1720_08110

PPAC:

PAP_07210

MBA:	Mbar_A3422

MBY:	MSBRM_1245 MSBRM_2785

MBW:	MSBRW_1312

MBAR:

MSBR2_1164 MSBR2_2742

MBAK:

MSBR3_1297 MSBR3_2679

MAC:	MA_1484 MA_2893 MA_3894 MA_4421

MMA:	MM_0718 MM_2499 MM_3299

MMAZ:

MmTuc01_0739 MmTuc01_2550 MmTuc01_3399

MMJ:	MSMAS_0599 MSMAS_1387 MSMAS_2202

MMAC:

MSMAC_0600 MSMAC_2252 MSMAC_2749

MVC:	MSVAZ_0959 MSVAZ_1325 MSVAZ_1805

MEK:	MSKOL_0928 MSKOL_1264 MSKOL_1782

MLS:	MSLAZ_1440 MSLAZ_1542 MSLAZ_2928

METM:

MSMTP_0646 MSMTP_0954 MSMTP_1509

MEF:	MSWH1_1330 MSWH1_1478 MSWH1_1898

MEQ:	MSWHS_1414 MSWHS_1853 MSWHS_3173

MSJ:	MSSAC_1463 MSSAC_2883 MSSAC_4107

MSZ:	MSSIH_1494 MSSIH_2538 MSSIH_3643

MSW:	MSSIT_1552 MSSIT_2581 MSSIT_3698

MTHR:

MSTHT_0217 MSTHT_0358 MSTHT_1727 MSTHT_2311

MTHE:

MSTHC_0364 MSTHC_0514 MSTHC_0969 MSTHC_1561

MHOR:

MSHOH_0251 MSHOH_1697 MSHOH_2811

MFZ:	AOB57_000445 AOB57_001340 AOB57_003910 AOB57_007820

MBU:	Mbur_0303 Mbur_0369 Mbur_0939 Mbur_1077 Mbur_1308

MMET:

MCMEM_0833 MCMEM_0997 MCMEM_1441 MCMEM_1598 MCMEM_1755

MELO:

J7W08_02385 J7W08_03355 J7W08_05920 J7W08_06945 J7W08_07805

MMH:	Mmah_0579 Mmah_0675 Mmah_1258 Mmah_1613

MHAZ:

BHR79_00515 BHR79_05660 BHR79_07245 BHR79_10225

MPOT:

BKM01_01750 BKM01_07890 BKM01_09925

MEV:	Metev_0262 Metev_0801 Metev_1607 Metev_1731

MZH:	Mzhil_0235 Mzhil_0513 Mzhil_0683 Mzhil_1608

MPY:	Mpsy_0099 Mpsy_1026 Mpsy_1467 Mpsy_2554

MZI:	HWN40_01470 HWN40_03330 HWN40_05930 HWN40_09670

MMAV:

RE476_00450

MSEB:

RE474_10185

MHZ:	Metho_0239 Metho_0947 Metho_1579 Metho_1933

MEHF:

MmiHf6_00880(kmo)

MEES:

MmiEs2_09160(thi4_2) MmiEs2_09170(thi4_3)

MTP:	Mthe_0044 Mthe_0513 Mthe_0671 Mthe_0714

MCJ:	MCON_1147 MCON_3250 MCON_3296

MHI:	Mhar_0556 Mhar_1078 Mhar_1156 Mhar_2172

MHU:

Mhun_1123

MRTJ:

KHC33_08510

MLA:

Mlab_0431

MEM:	Memar_0506 Memar_1711

MBG:	BN140_1582

MEMA:

MMAB1_2023

MCHK:

MchiMG62_06300

MSUM:

OH143_09245

MRC:	R6Y96_10195

MPI:

Mpet_1752

MEND:

L6E24_01525

MEFW:

F1737_03510

MAQE:

RJ40_04645

MFK:	E2N92_04850

MOU:	OU421_10180

MESB:

L1S32_01385

MANQ:

L1994_04690

MBN:

Mboo_1945

MFO:	Metfor_1011

MPL:

Mpal_0962

MPD:	MCP_0504 MCP_1168 MCP_1480

MEZ:	Mtc_0895(bchP) Mtc_1643 Mtc_1724

RCI:	RCIX2051(bchP) RCIX2708

HAL:

VNG_0468C

HSL:

OE_1699R

HANR:

LJ422_01955

HDL:	HALDL1_06480

HHB:

Hhub_1531

HAGS:

JT689_03235

HABO:

JRZ79_01735

HNO:	LT974_03030

HLU:	LT972_10470

HALH:

HTSR_0966

HHSR:

HSR6_0997

HSU:	HLASF_0746

HSF:	HLASA_0743

SALR:

FQU85_11230

HALR:

EFA46_006370 EFA46_006470

HJE:	HacjB3_14420

HDO:	MUK72_09380

HALX:

M0R89_10965

HAXZ:

M0R88_11400

HAYC:

NGM10_04900

HAXY:

NGM07_16955

SALI:

L593_01650

SAIM:

K0C01_10790

HARA:

AArcS_1790(fixC3)

HMA:

rrnAC0726

HHI:

HAH_1373

HHN:	HISP_07025

HAB:	SG26_14865

HTA:	BVU17_06685

HALJ:

G9465_08440 G9465_08805 G9465_20450

HSIN:

KDQ40_06605

NPH:

NP_4564A

NMO:	Nmlp_2334 Nmlp_3608

NHO:	HWV23_05715

NSAL:

HWV07_05475

HUT:	Huta_0881 Huta_1007 Huta_2954

HTI:	HTIA_0743 HTIA_2555

HALA:

Hrd1104_04765 Hrd1104_09045

HMU:	Hmuk_1955 Hmuk_2206 Hmuk_3091 Hmuk_3127

HALZ:

E5139_02700 E5139_02875 E5139_12890 E5139_14170

HALL:

LC1Hm_1280 LC1Hm_1619(fixC) LC1Hm_2428(fixC3) LC1Hm_2469(fixC4)

HAZP:

GBQ70_02700 GBQ70_12905 GBQ70_14185

HALI:

BV210_03410

HSN:	DV733_10365

HDS:	HSR122_0270(fixC)

HRR:	HZS55_18830 HZS55_20705

HPEL:

HZS54_21655 HZS54_22270 HZS54_24195

HLT:	I7X12_15485 I7X12_16545 I7X12_17600

HARC:

HARCEL1_04790

SSAI:

N0B31_03370

HWA:

HQ_1534A

HWC:	Hqrw_1635 Hqrw_3314

HVO:

HVO_1799

HME:	HFX_1905(fixC)

HGI:	ABY42_08860

HALE:

G3A49_12170

HLS:	KU306_03510

HLN:	SVXHx_2785(ggr)

HBO:	Hbor_11300

HAQ:	DU484_09565 DU484_17775

HAJ:	DU500_00815 DU500_09815

HAER:

DU502_06905 DU502_07185 DU502_16565

HRA:	EI982_07520 EI982_14380

HLM:	DV707_07230

HALM:

FCF25_11425

HLA:

Hlac_0926

HALP:

DOS48_03545

HALB:

EKH57_07685

HEZZ:

EO776_04760

HALQ:

Hrr1229_002660

HSS:	J7656_12430

HSAI:

HPS36_02425

HAZZ:

KI388_02310

SRUB:

C2R22_05450

HAE:	halTADL_1048

HALN:

B4589_000260

HALG:

HUG10_08475

HALU:

HUG12_17860

HDF:	AArcSl_1381 AArcSl_1813

HAAA:

AArcCO_0174(fixC)

HAH:	Halar_0855

HTU:	Htur_1377 Htur_3081

HSAL:

JMJ58_01855 JMJ58_05545 JMJ58_12995 JMJ58_22355

HAKZ:

J0X25_02870 J0X25_13780

NMG:	Nmag_0668 Nmag_1523 Nmag_2507 Nmag_2778

HXA:	Halxa_3925 Halxa_3960

NAT:	NJ7G_0898 NJ7G_2427

NPE:	Natpe_0646 Natpe_1962 Natpe_3244

NVR:	FEJ81_03545

NPL:	FGF80_01135 FGF80_07435

NAY:	HYG81_07440

HALY:

HYG82_09140 HYG82_16990

HJT:	DVR14_12450

HLO:	J0X27_13130

NGE:	Natgr_0786 Natgr_1266 Natgr_3103

HRU:	Halru_1246 Halru_2474

SAWL:

NGM29_01025

HALV:

NGM15_10625

NOU:	Natoc_0699 Natoc_2139 Natoc_4277

HLR:	HALLA_08655 HALLA_13160 HALLA_17630

HLC:	CHINAEXTREME15935 CHINAEXTREME19570

NAJ:	B1756_02305 B1756_04290 B1756_12495

NAG:	AArcMg_1023 AArcMg_2971 AArcMg_3119

NAN:	AArc1_0731 AArc1_2601 AArc1_3025

NARA:

QQ977_14385

NBG:	DV706_00945 DV706_09380 DV706_16325 DV706_19090

NAS:	GCU68_02695 GCU68_12755

HDA:	BB347_05735 BB347_10350 BB347_10530

NAC:	AQV86_03970

MELU:

MTLP_05820 MTLP_05840 MTLP_09940

MEAM:

MU439_04990

MEAE:

QEN48_05175

TAC:

Ta0516

TVO:	TVG1046096(TVG1046096) TVG1579590(TVG1579590)

PTO:	PTO0568 PTO0896

FAC:	FACI_IFERC01G0166

FAI:

FAD_1079

CDIV:

CPM_0295 CPM_0485 CPM_0894

TAR:	TALC_00223 TALC_00435 TALC_00774

MAX:	MMALV_02090 MMALV_03590 MMALV_08730

MER:	MMINT_02130 MMINT_12590 MMINT_13170 MMINT_17750

MEAR:

Mpt1_c01650 Mpt1_c12530

MEUZ:

KRP56_01915

MARC:

AR505_0892 AR505_1433 AR505_1618

ABI:

Aboo_0578

ACF:	AciM339_0374 AciM339_0468

SMR:

Smar_1462

DKA:

DKAM_0159

DFD:	Desfe_0234

DMU:	Desmu_0290

TAG:

Tagg_0378

THG:	TCELL_1246

HBU:

Hbut_1257

STO:

STK_04940

SOH:	D1869_02295

SSO:

SSO2353

SOL:

Ssol_0166

SSOA:

SULA_0158

SSOL:

SULB_0159

SSOF:

SULC_0158

SSHI:

J5U23_01149

SCAS:

SACC_19360

SIS:	LS215_0182

SIA:	M1425_0151

SIM:	M1627_0151

SID:

M164_0170

SIY:	YG5714_0155

SIN:	YN1551_2754

SII:

LD85_0155

SIH:

SiH_0155

SIR:

SiRe_0151

SIC:

SiL_0142

SULA:

BFU36_10465

SULE:

GFS03_02305

SULO:

GFS33_08920

MSE:

Msed_0681

MEMJ:

MJ1HA_0791

MCN:

Mcup_1399

MHK:	DFR87_03150

MPRU:

DFR88_03175

MTEN:

GWK48_08960

MJN:	MjAS7_1447

AHO:

Ahos_2154

AMAN:

B6F84_03335

ABRI:

DFR85_06060

ASUL:

DFR86_03340

AAMB:

D1866_05750

ACIH:

HS5_09650

SACD:

HS1genome_0804

SAZO:

D1868_10400

STEP:

IC006_2737

SMET:

RQ359_001719

CMA:

Cmaq_0840

VDI:

Vdis_1715

VMO:

VMUT_2242

TPE:	Tpen_0114 Tpen_0718

THB:	N186_01490 N186_04950

TCB:	TCARB_0050 TCARB_1382

THF:	MA03_00905 MA03_06135

THEL:

IG193_04155 IG193_06980

ACIA:

SE86_02030

FFO:	FFONT_1180

NMR:

Nmar_0631

NIR:	NSED_03245

NKR:	NKOR_03230

NID:	NPIRD3C_1636

NIN:	NADRNF5_0722 NADRNF5_1519

NIW:	Nisw_01750

NCL:	C5F47_05915

NOX:	C5F49_05755 C5F49_06640

NUE:	C5F50_04660

NIP:	NsoK4_05210

NZT:	NZOSNM25_001364

NCT:	NMSP_0453 NMSP_1055

NIC:	DSQ20_03360

NGA:	Ngar_c10460 Ngar_c11500 Ngar_c18750

NVN:	NVIE_003360 NVIE_011700

NEV:	NTE_01655 NTE_02579

TAA:	NMY3_01977 NMY3_02141 NMY3_02989

NFN:	NFRAN_0449 NFRAN_2927

NCV:

NCAV_0324

CSY:	CENSYa_0520 CENSYa_1317

CSU:	CSUB_C1349 CSUB_C1610

NBV:	T478_0510 T478_0975

TAH:	SU86_000125 SU86_003010

NIU:	DSQ19_03605

NDV:	NDEV_0107 NDEV_1206

KCR:	Kcr_0058 Kcr_1359

BARC:

AOA65_1634

FLT:	Sv326_0975

LOKI:

Lokiarch_51240

LOB:	NEF87_004200

PSYT:

DSAG12_02297

AGW:	QT03_C0001G0827

» show all

Reference

1 [PMID:17288560]

Authors

Murakami M, Shibuya K, Nakayama T, Nishino T, Yoshimura T, Hemmi H

Title

Geranylgeranyl reductase involved in the biosynthesis of archaeal membrane lipids in the hyperthermophilic archaeon Archaeoglobus fulgidus.

Journal

FEBS J 274:805-14 (2007)
DOI:10.1111/j.1742-4658.2006.05625.x

Sequence

[afu:AF_0464]

Reference

2 [PMID:18375567]

Authors

Sato S, Murakami M, Yoshimura T, Hemmi H

Title

Specific partial reduction of geranylgeranyl diphosphate by an enzyme from the thermoacidophilic archaeon Sulfolobus acidocaldarius yields a reactive prenyl donor, not a dead-end product.

Journal

J Bacteriol 190:3923-9 (2008)
DOI:10.1128/JB.00082-08

Reference

3 [PMID:21515284]

Authors

Sasaki D, Fujihashi M, Iwata Y, Murakami M, Yoshimura T, Hemmi H, Miki K

Title

Structure and mutation analysis of archaeal geranylgeranyl reductase.

Journal

J Mol Biol 409:543-57 (2011)
DOI:10.1016/j.jmb.2011.04.002

Reference

4 [PMID:24214941]

Authors

Isobe K, Ogawa T, Hirose K, Yokoi T, Yoshimura T, Hemmi H

Title

Geranylgeranyl reductase and ferredoxin from Methanosarcina acetivorans are required for the synthesis of fully reduced archaeal membrane lipid in Escherichia coli cells.

Journal

J Bacteriol 196:417-23 (2014)
DOI:10.1128/JB.00927-13

Other DBs

ExplorEnz - The Enzyme Database:

1.3.7.11

IUBMB Enzyme Nomenclature:

1.3.7.11

ExPASy - ENZYME nomenclature database:

1.3.7.11

BRENDA, the Enzyme Database:

1.3.7.11

DBGET integrated database retrieval system