KEGG ENZYME: 1.3.7.2

ENZYME: 1.3.7.2

Entry

EC 1.3.7.2                  Enzyme

Name

15,16-dihydrobiliverdin:ferredoxin oxidoreductase;
PebA

Class

Oxidoreductases;
Acting on the CH-CH group of donors;
With an iron-sulfur protein as acceptor

Sysname

15,16-dihydrobiliverdin:ferredoxin oxidoreductase

Reaction(IUBMB)

15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXalpha + reduced ferredoxin [RN:R05818]

Reaction(KEGG)

R05818

Substrate

15,16-dihydrobiliverdin [CPD:C11630];
oxidized ferredoxin [CPD:C00139]

Product

biliverdin IXalpha;
reduced ferredoxin [CPD:C00138]

Comment

Catalyses the two-electron reduction of biliverdin IXalpha at the C15 methine bridge. It has been proposed that this enzyme and EC 1.3.7.3, phycoerythrobilin:ferredoxin oxidoreductase, function as a dual enzyme complex in the conversion of biliverdin IXalpha into phycoerythrobilin.

History

EC 1.3.7.2 created 2002

Pathway

ec00860

Porphyrin metabolism

ec01110

Biosynthesis of secondary metabolites

Orthology

K05369

15,16-dihydrobiliverdin:ferredoxin oxidoreductase

Genes

RHER:

EHE19_004630

SYD:	Syncc9605_0423

SYE:	Syncc9902_1906

SYG:

sync_0491

SYR:	SynRCC307_2061(pebA)

SYX:	SynWH7803_0482(pebA)

SYNK:

KR100_03630

SYNR:

KR49_11190

SYND:

KR52_00295

SYH:	Syncc8109_0441(pebA)

SYNW:

SynWH8103_02324(pebA)

SYNY:

BM449_08980

SYW:	SYNW2020(pebA)

PMA:	Pro_1749(pebA)

PMM:	PMM1593(pebA)

PMT:

PMT_1686

PMN:	PMN2A_1168

PMI:	PMT9312_1685

PMB:	A9601_18021(pebA)

PMC:	P9515_17801(pebA)

PMF:	P9303_22431(pebA)

PMG:	P9301_17851(pebA)

PMH:	P9215_18661(pebA)

PMJ:	P9211_17141(pebA)

PME:	NATL1_20431(pebA)

PRC:

EW14_1950

PRM:

EW15_2114

CMP:	Cha6605_4070

KOV:	K9N68_31090

LSK:	J5X98_04835

PSEU:

Pse7367_3941

PGX:	OA858_05010

CHON:

NIES4102_25510

GEN:	GM3709_2917

GEE:	GM3708_1497

LEP:	Lepto7376_0653

MIQ:	B5D77_00265

CWA:	CwatDRAFT_0676 CwatDRAFT_2853

CYP:	PCC8801_4517

CYC:	PCC7424_5728

CYJ:	Cyan7822_4038

TER:

Tery_5051

PRUN:

PCC7821_02376(pebA)

ONI:	Osc7112_1022

MPRO:

BJP34_30485

MIC:	Mic7113_4743

GVI:	glr1260(pebA)

GLJ:

GKIL_4295

GML:	ISF26_01180

NPU:	Npun_R0730

NFL:	COO91_10293

NOE:	CLI64_20495

NSH:

GXM_07874

NED:	HUN01_30145

HBQ:	QI031_17690

CALT:

Cal6303_4022

CALH:

IJ00_13705

CALN:

NIES2098_31940

CALS:

NIES3974_24670

ALAX:

NIES50_52960

PLP:	Ple7327_0114

SCS:	Sta7437_0248

STAN:

STA3757_01140

CVL:	J8C06_01670

CHLO:

J8C02_08935

» show all

Reference

1 [PMID:11283349]

Authors

Frankenberg N, Mukougawa K, Kohchi T, Lagarias JC.

Title

Functional genomic analysis of the HY2 family of ferredoxin-dependent bilin reductases from oxygenic photosynthetic organisms.

Journal

Plant Cell 13:965-78 (2001)
DOI:10.1105/tpc.13.4.965

Sequence

[npu:Npun_R0730] [pmm:PMM1593]

Other DBs

ExplorEnz - The Enzyme Database:

1.3.7.2

IUBMB Enzyme Nomenclature:

1.3.7.2

ExPASy - ENZYME nomenclature database:

1.3.7.2

BRENDA, the Enzyme Database:

1.3.7.2

CAS:	347401-20-1

DBGET integrated database retrieval system