KEGG ENZYME: 1.3.98.5

ENZYME: 1.3.98.5

Entry

EC 1.3.98.5                 Enzyme

Name

hydrogen peroxide-dependent heme synthase;
coproheme III oxidative decarboxylase;
hemQ (gene name)

Class

Oxidoreductases;
Acting on the CH-CH group of donors;
With other, known, physiological acceptors

Sysname

Fe-coproporphyrin III:hydrogen peroxide oxidoreductase (decarboxylating)

Reaction(IUBMB)

Fe-coproporphyrin III + 2 H2O2 = protoheme + 2 CO2 + 4 H2O (overall reaction) [RN:R11522];
(1a) Fe-coproporphyrin III + H2O2 = harderoheme III + CO2 + 2 H2O [RN:R12454];
(1b) harderoheme III + H2O2 = protoheme + CO2 + 2 H2O [RN:R12455]

Reaction(KEGG)

R11522 R12454 R12455

Substrate

Fe-coproporphyrin III [CPD:C21284];
H2O2 [CPD:C00027];
harderoheme III [CPD:C22173]

Product

protoheme [CPD:C00032];
CO2 [CPD:C00011];
H2O [CPD:C00001];
harderoheme III [CPD:C22173]

Comment

The enzyme participates in a heme biosynthesis pathway found in Gram-positive bacteria. The initial decarboxylation step is fast and yields the three-propanoate harderoheme isomer III. The second decarboxylation is much slower. cf. EC 1.3.98.6, SAM-dependent heme synthase.

History

EC 1.3.98.5 created 2019

Pathway

ec00860

Porphyrin metabolism

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K00435

hydrogen peroxide-dependent heme synthase

K25033

hydrogen peroxide-dependent heme synthase

Genes

SDO:	SD1155_05710

DMM:	dnm_014420

BSU:	BSU37670(ywfI)

BSR:

I33_3915

BSL:

A7A1_0186

BSH:	BSU6051_37670(ywfI)

BSY:	I653_18480

BSUT:

BSUB_04003(hemQ)

BSUL:

BSUA_04003(hemQ)

BSUS:

Q433_20750

BSO:	BSNT_10425(ywfI)

BSN:	BSn5_09825

BSQ:	B657_37670(hemQ)

BSX:	C663_3672(ywfI)

BSP:	U712_18985

BSS:	BSUW23_18605(ywfI)

BST:

GYO_4153

BIT:	BIS30_08550

BLI:	BL03956(ywfI)

BLD:	BLi03998(ywfI)

BLH:	BaLi_c40120(ywfI)

BAY:	RBAM_034860

BAQ:	BACAU_3515(ywfI)

BYA:	BANAU_3668(ywfI)

BAMP:

B938_17890

BQY:	MUS_4145(ywfI)

BAML:

BAM5036_3416(hemQ)

BAMA:

RBAU_3624(hemQ)

BAMN:

BASU_3400(hemQ)

BAMB:

BAPNAU_3682(ywfI)

BAMT:

AJ82_19675

BAMY:

V529_37580(ywfI)

BMP:	NG74_03661

BAO:	BAMF_3599(ywfI)

BAZ:	BAMTA208_19065(ywfI)

BQL:	LL3_03911(ywfI)

BXH:	BAXH7_03903(ywfI)

BAMI:

KSO_001630

BAMC:

U471_36310

BAMF:

U722_18625

BSIA:

CWD84_01695

BAE:	BATR1942_16800

BVM:	B9C48_17840

BSON:

S101395_00387

BHT:	DIC78_12140

BMOJ:

HC660_36750(hemQ)

BTEQ:

G4P54_19425

BIQ:	AN935_19080

BSTR:

QI003_22340(hemQ)

BAN:

BA_5637

BAR:

GBAA_5637

BAT:

BAS5239

BAH:	BAMEG_5682

BAI:

BAA_5664

BAX:	H9401_5379

BANT:

A16_56490

BANR:

A16R_57170

BANS:

BAPAT_5404

BANH:

HYU01_27515

BANV:

DJ46_4284

BCE:

BC5388

BCA:

BCE_5517

BCZ:	BCE33L5086

BCR:	BCAH187_A5567

BCB:	BCB4264_A5511

BCU:	BCAH820_5483

BCG:	BCG9842_B5440

BCQ:

BCQ_5229

BCX:

BCA_5540

BAL:	BACI_c53830

BNC:

BCN_5316

BCF:

bcf_27060

BCER:

BCK_08415

BCY:	Bcer98_3909

BTK:	BT9727_5069

BTL:

BALH_4887

BTB:	BMB171_C4983

BTT:

HD73_5801

BTHR:

YBT1520_28740

BTHI:

BTK_28590

BTC:	CT43_CH5428

BTF:	YBT020_26870

BTM:

MC28_4621

BTG:	BTB_c55880

BTI:

BTG_21445

BTN:	BTF1_25425

BTHT:

H175_ch5519

BTHU:

YBT1518_30300

BTW:

BF38_1111

BTHY:

AQ980_02350

BWE:	BcerKBAB4_5181

BWW:

bwei_4395

BMYO:

BG05_621

BTY:	Btoyo_2584

BMYC:

DJ92_2476

BBY:	CY96_26065

BWD:	CT694_28950

BTRO:

FJR70_21085

BMOB:

MLA2C4_27920

BNT:	GSN03_25810

BPAC:

LMD38_26910

BPAN:

NLJ82_26580

BALU:

QRY64_29720

BPU:

BPUM_3416

BPUM:

BW16_18140

BPUS:

UP12_17585

BIF:	N288_24050

BMET:

BMMGA3_16270

BSM:	BSM4216_3736

BGY:

BGLY_4402

BWH:	A9C19_00345

BXI:	BK049_09805

BALT:

CFN77_18045

BAER:

BAE_05945

BSAF:

BSL056_18685

BFD:	NCTC4823_00391

BSHI:

LGQ02_20260

BBAD:

K7T73_19010

BCAB:

EFK13_19395

BRY:	M0696_19145

BJS:

MY9_3858

BACI:

B1NLA3E_21765

GST:	HW35_09400

BACW:

QR42_17140

BACP:

SB24_11265

BACB:

OY17_01095

BACO:

OXB_1378

BACY:

QF06_17275

BACL:

BS34A_40850(ywfI)

BALM:

BsLM_3797

BACS:

AUL54_12265

BACQ:

DOE78_23975

BACA:

FAY30_25240

BAQU:

K6959_15445

BZH:	NF868_15770

BHAI:

KJK41_21125

BCAO:

LC087_12920

BARD:

QRY57_26450

BAEI:

RE735_02205

BCO:	Bcell_4134

BHK:	B4U37_20670

BCOH:

BC6307_22325

BCIR:

C2I06_17085

NTX:	NQZ71_03230

BMQ:

BMQ_5203

BMD:

BMD_5189

BMH:	BMWSH_0076

BMEG:

BG04_2197

BEO:

BEH_23695

BFX:	BC359_01695 BC359_07410

PKS:	IE339_23015

BHA:

BH3825

BKW:	BkAM31D_24750

BCL:

ABC3912

BLE:	BleG1_3772

SHUA:

PQ477_06500

BGI:	BGM20_13095

BPF:	BpOF4_07220(ywfI)

BON:	A361_26270

BKO:	CKF48_11985

CGOT:

J1899_21190

CSUA:

IM538_22885

CFIR:

NAF01_24135

CSOA:

LIS82_25520

CSPG:

LS684_19575

CPSS:

M5V91_22985

BDA:	FSZ17_22240

OIH:

OB3023

OCN:	CUC15_17735

OCB:	CV093_19180

OJD:	NP439_21970

OON:	NP440_20440

GKA:

GK3416

GTE:	GTCCBUS3UF5_38380

GTK:	GT3570_16780

GTM:	GT3921_01885

GLI:	GLN3_09805

BCAL:

CWI35_10940

GTN:

GTNG_3362

GWC:	GWCH70_3365

GYC:	GYMC61_3473

GYA:	GYMC52_3505

GCT:	GC56T3_3401

GMC:	GY4MC1_3758

GGH:	GHH_c35120(ywfI)

GJF:	M493_17870

GEA:	GARCT_03400

GEL:	IB49_09650

GSE:	GT50_08830

GSR:	GS3922_16185

GEJ:	A0V43_14760

GZA:	IC807_13110

GTH:	Geoth_3863

PTL:	AOT13_03485

PTB:	DER53_04330

PCAL:

BV455_01880

PARG:

PspKH34_37280

AFL:

Aflv_2762

AGN:	AFK25_14125

ANM:	GFC28_2763

AAMY:

GFC30_304

ANL:	GFC29_2671

AND:	GRQ40_17890

ACAI:

ISX45_15190

ASED:

IRT44_01670

LSP:

Bsph_0946

LGY:	T479_02470

LFU:	HR49_21280

LYS:	LBYS11_02565

LYB:	C3943_03210

LYZ:	DCE79_02110

LYG:	C1N55_04030

LPAK:

GDS87_02615

LAGR:

FJQ98_03280

LMAC:

I6G82_15865

LYC:	FH508_0002415

LCAP:

ICJ70_21905

LYP:	MTP04_06880(ywfI)

LIU:	OU989_02295

LLB:	R6U77_02440(hemQ)

HHD:	HBHAL_4659

HMN:	HM131_03875

HLI:

HLI_14195

HNZ:	P9989_19120

HSAN:

MUN89_04910

HSHI:

MUO14_08890

HAMY:

MUO15_16535

TAP:	GZ22_15085

TAID:

KS242_14520

VIR:	X953_17545

VHL:	BME96_17035

VIG:	BKP57_08490

VIL:	CFK37_07615

VNE:	CFK40_02905

VPN:	A21D_00986

VIM:	GWK91_11855

VPT:	KBP50_20015

VNT:	OLD84_17385

VIK:	KFZ58_16915

LAO:	AOX59_15485

LEX:	Len3610_13815

FPN:	ABE65_020435

FAR:	ABE41_019595

FEC:	QNH15_25420

SJE:	AAV35_002085

APAK:

AP3564_04145

ACOP:

RI196_17750(hemQ)

BSJ:	UP17_24425

BMUR:

ABE28_023110

PBUT:

DTO10_11010

PASA:

BAOM_4922(cld)

PPSR:

I6J18_15355

PFRI:

L8956_25890

AQT:	FN924_16900

RAX:	KO561_17685

BTHV:

CQJ30_18380

PSYH:

D0S48_09280

PSYO:

PB01_03105

PSYB:

KD050_14205

PRD:	F7984_18285

GRC:	GI584_21150

GCS:	MUN88_09180

GSM:	MUN87_09645

RUE:	DT065_10725

SALE:

EPH95_11350

SCIB:

HUG20_18670

SCIA:

HUG15_22380

POF:	GS400_18450

PCHU:

QNI29_19720

NMK:	CHR53_27320

NTM:	BTDUT50_02195

NDT:	L1999_28780

NCM:	QNK12_16750 QNK12_30530

NNV:	QNH39_27260

MEKU:

HUW50_08350

MSEM:

GMB29_25875

MDG:	K8L98_24060

MLIT:

KDJ21_006190

AIA:	AWH56_006585

BLEN:

NCTC4824_03925

SEDD:

ERJ70_17445

BVQ:	FHE72_22665

RMF:	D5E69_21270

RAZ:	U9J35_21945(hemQ)

BCK:	BCO26_2853

BAG:

Bcoa_1405

BCOA:

BF29_2111

BVJ:	I5776_20220

BOU:	I5818_24750

CTHU:

HUR95_16880

BBEV:

BBEV_0110

BSE:

Bsel_3224

MCUI:

G8O30_12755

GAJ:	MY490_21505

PSUA:

FLK61_40270

SLMS:

MM221_07210

MJO:	FOF60_23595

MSUT:

LC048_23750

FHL:	OE105_11695

FAF:	OE104_14025

SFOR:

QNH23_17610

ECTO:

MUG87_12025

ALKL:

MM271_22965

ALKG:

MOJ78_19865

PHJ:	LC071_10705

DOM:	RRU94_09690(hemQ)

AHAL:

FTX54_015855(hemQ)

HYI:	K2M58_10890

STEA:

C0679_14535

PUK:	PU629_01490

SA0544

SAV:

SAV0587

SAW:

SAHV_0585

SAH:	SaurJH1_0625

SAJ:	SaurJH9_0610

SAM:

MW0542

SAS:

SAS0546

SAR:

SAR0593

SAC:

SACOL0633

SAX:	USA300HOU_0580

SAA:	SAUSA300_0569

SAO:	SAOUHSC_00573

SAE:

NWMN_0550

SAD:

SAAV_0549

SUU:	M013TW_0575

SUV:	SAVC_02520

SUE:	SAOV_0621c

SUJ:	SAA6159_00540

SUK:	SAA6008_00594

SUC:

ECTR2_540

SUT:	SAT0131_00649

SUQ:	HMPREF0772_12601

SUZ:

MS7_0576

SUD:	ST398NM01_0661

SUX:	SAEMRSA15_05150

SUW:	SATW20_06560

SUG:

SAPIG0661

SUF:	SARLGA251_05220

SAUA:

SAAG_01009

SAUE:

RSAU_000539

SAUN:

SAKOR_00577

SAUS:

SA40_0528

SAUU:

SA957_0543

SAUG:

SA268_0541

SAUZ:

SAZ172_0589

SAUT:

SAI1T1_2004510

SAUJ:

SAI2T2_1004530

SAUK:

SAI3T3_1004520

SAUQ:

SAI4T8_1004510

SAUV:

SAI7S6_1004520

SAUW:

SAI5S5_1004480

SAUX:

SAI6T6_1004490

SAUY:

SAI8T7_1004520

SAUF:

X998_0628

SAB:

SAB0537c

SUY:	SA2981_0564

SAUB:

C248_0662

SAUM:

BN843_5800

SAUC:

CA347_602

SAUR:

SABB_00636

SAUI:

AZ30_02965

SAUD:

CH52_02825

SAMS:

NI36_02925

SUH:	SAMSHR1132_05310

SER:

SERP0235

SEP:

SE_0358

SEPP:

SEB_00280

SEPS:

DP17_1665

SHA:

SH2405

SHH:	ShL2_02200

SSP:

SSP2125

SCA:

SCA_0241

SLG:	SLGD_02298

SLN:	SLUG_22140

SSD:	SPSINT_0283

SDT:

SPSE_2174

SDP:	NCTC12225_02393

SWA:	A284_10370

SPAS:

STP1_1673

SXY:	BE24_00725

SXL:	SXYLSMQ121_2109

SXO:	SXYL_02261

SHU:	SHYC_10700

SCAP:

AYP1020_2337

SSCH:

LH95_10290

SSCZ:

RN70_11025

SAGQ:

EP23_11460

SEQO:

SE1039_04160

SSIF:

AL483_08620

SCV:	A4G25_06475

SPET:

CEP67_09940

SLZ:	B5P37_07385

SCOH:

BZ166_02600

SNL:	BJD96_11945

SKL:	C7J89_12510

SFQ:	C7J90_01725

SHOM:

EGX58_03260

SMUS:

C7J88_08460

SCAR:

DWB96_11595

SCHR:

DWB92_10855

SARL:

SAP2_21780

SPIC:

SAMEA4384060_2281

SSH:	NCTC13712_00539

SSIM:

SAMEA4384339_0535

SDB:	CNQ82_12765

SLLO:

ISP08_10775

SAUL:

I6G39_01990

SSAC:

I6I31_05710

SRAI:

LN051_09970

SPSD:

JMB28_11470

STAS:

HYI43_10805

SURY:

MUA21_01615

SEDA:

MNY58_11445

SCAQ:

QMO72_11365

SDEV:

Q2T90_08220

SROT:

ML435_02715

STAP:

AOB58_1342

SSCU:

CEP64_11385

SFF:	FOB90_09175

SSTE:

SAMEA4384403_2280

MLEN:

H3V22_10430

MVT:	I6J10_12110

MACR:

BHM04_11555

MARY:

LAU42_10970

MBRU:

MGG13_10360

MEPI:

KFV12_12410

MEQU:

KFV11_10560

MBOC:

QSV55_10525

MCL:

MCCL_1834

MCAK:

MCCS_23810

MBOE:

HT586_11525

SHV:	AAT16_13205

JEA:	JEM45_08965

NAMP:

KPF49_07160

NMY:	CJ229_005250(hemQ)

SBAC:

BVH56_01105

LMO:

lmo2113

LMN:	LM5578_2316

LMY:	LM5923_2267

LMT:	LMRG_01267

LMOC:

LMOSLCC5850_2178

LMOE:

BN418_2544

LMOB:

BN419_2550

LMOD:

LMON_2187

LMOW:

AX10_04825

LMOQ:

LM6179_02888

LMR:	LMR479A_2224(hemQ)

LMOM:

IJ09_14370

LMF:	LMOf2365_2146

LMC:	Lm4b_02135

LMOG:

BN389_21440

LMP:

MUO_10840

LMOL:

LMOL312_2129

LMOJ:

LM220_14566

LMOZ:

LM1816_07648

LMOX:

AX24_08430

LMH:	LMHCC_0433

LMQ:

LMM7_2215

LML:	lmo4a_2174

LMG:	LMKG_00204

LMS:

LMLG_0313

LMJ:	LMOG_01106

LMW:	LMOSLCC2755_2177

LMX:	LMOSLCC2372_2181

LMZ:	LMOSLCC2482_2175

LMON:

LMOSLCC2376_2070

LMOS:

LMOSLCC7179_2089

LMOO:

LMOSLCC2378_2141

LMOY:

LMOSLCC2479_2178

LMOT:

LMOSLCC2540_2210

LMOA:

LMOATCC19117_2135

LMOK:

CQ02_10950

LMV:	Y193_04955

LIN:

lin2218

LWE:

lwe2132

LSG:

lse_2102

LIV:

LIV_2104

LII:	JL52_11045

LIW:	AX25_11225

LIA:	JL58_11220

LIO:	JL53_11720

LWI:	UE46_04385

LGZ:	NCTC10812_02027

LMAR:

LAX80_010355

LNW:	OTR81_00655

BTHS:

CNY62_03870

ESI:

Exig_0217

EAT:	EAT1b_1445

EAN:

Eab7_0205

EXM:	U719_01100

EXU:	ESP131_03530

EAP:	KB235_03320

EACE:

KKI46_01355

EAUR:

NMQ00_01750

EMM:	PTI97_12630

EPF:	OE059_01605

BBE:	BBR47_45550

BLR:	BRLA_c040460

BFM:	BP422_18425

BAGR:

BA6348_08735

BRW:	GOP56_12860

BCHS:

JNE38_23750

BCOP:

JD108_05545

BPAB:

PSE45_21295

BHUI:

LOK74_16195

BAYD:

BSPP4475_04190

BBOR:

RFB14_05830

BRUM:

NDK47_06550

PJD:	Pjdr2_4832

GYM:	GYMC10_5450

PPY:

PPE_03879

PPM:	PPSC2_20370(ywfI)

PPO:	PPM_4082(ywfI)

PPOL:

X809_36505

PPQ:	PPSQR21_041190(ywfI)

PPOY:

RE92_16820

PMS:	KNP414_03744

PMQ:	PM3016_1139

PMW:

B2K_05800

PTA:	HPL003_01340 HPL003_02245

PLV:	ERIC2_c29580

PSAB:

PSAB_19360

PDU:	PDUR_21990

PBD:	PBOR_30050

PGM:	PGRAT_26950

POD:	PODO_25700

PAEN:

P40081_31545

PAEF:

R50345_25635

PAEQ:

R50912_28380

PSTE:

PSTEL_22005

PAEA:

R70723_27190

PAEE:

R70331_26270

PAEH:

H70357_29035

PAEJ:

H70737_25440

PBJ:	VN24_16000

PIH:	UB51_01730

PRI:

PRIO_5637

PSON:

JI735_03165

PPEO:

ABE82_20420

PNP:	IJ22_30930

POW:	IJ21_13710

PBV:	AR543_20595

PXL:	BS614_28260

PYG:	AWM70_14315

PSWU:

SY83_00030

PDH:	B9T62_26180

PIB:	BBD41_18905

PCX:	LPB68_07015

PKB:	B4V02_04940

PAIH:

ASL14_17495

PVO:	PVOR_29444

PLW:	D5F53_02820

PLEN:

EIM92_08855

PPSC:

EHS13_08605

PLUT:

EI981_23705

PALB:

EJC50_10970

PCHI:

PC41400_25470

PBK:	Back11_29950

PPRT:

ET464_19480

PBAC:

HUB98_11725

PRZ:	GZH47_07600

PLYC:

GXP70_08790

PSOP:

KP014_26040

PTRI:

KDC22_27480

PALO:

E6C60_3442

PCEL:

HUB94_21425

PTJ:	JRJ22_24230

PALR:

HGI30_17830

PTHI:

NDS46_06830

PKA:	PQ456_17860

PUI:	PUW25_20795

PMAH:

PTQ21_31220

PAMY:

P9222_11850

PDY:	QJQ58_15520

PMAE:

LMZ02_30515

PWN:	QNH46_19750

PSPN:

L1F29_08005

PPOG:

QPK24_19840

PAUN:

MJA45_06330

PHK:	SK066_05190(hemQ)

PNK:	AASFL403_01170

PPAB:

KET34_26580 KET34_28630

PKP:	SK3146_05524

TCO:	Theco_2742

ANX:	ACH33_04545

ASOC:

CB4_01234

ATHE:

K3F53_14360

COH:	EAV92_01500

COHN:

KCTCHS21_44860

CCHL:

FPL14_06415

CHEB:

HH215_13725

SACA:

FFV09_06435

AAC:

Aaci_1765

AAD:

TC41_1664

AFX:	JZ786_08640

AACO:

K1I37_12165

ACUR:

JZ785_12450 JZ785_16020

ADAU:

NZD86_11435

AFAS:

NZD89_13605

ACYC:

JI721_14130

BTS:

Btus_1292

KYR:	CVV65_09790

TUM:	CBW65_11530

TAB:	CIG75_16735

EFF:	skT53_18740

SIV:

SSIL_3430

SSIL:

SOLI23_01285

SOB:	CSE16_02175

PLN:	Plano_2453

PKU:	AUO94_03355

PRT:	AUC31_13850

PLL:	I858_010520

PANA:

BBH88_06660

PDG:	BCM40_02930

PHC:	BBI08_09510

PMAR:

B0X71_15305

PPLA:

BBI15_08460

PFAE:

AJGP001_14195

PLX:	CW734_14515

PMAT:

BBI11_14085

PDEC:

H1Q58_13390

PGQ:	FK545_03485

JEO:

JMA_31060

KUR:	ASO14_2586

KZO:	NCTC404_00525

SPSY:

AZE41_19750

SPOR:

SporoP33_11210

SPOP:

SporoP37_11625

SURE:

SporoP32a_11905

SPOS:

DV702_15870

SPAE:

E2C16_11800

SPOO:

J3U78_18415

SURL:

BI350_15885

STHO:

QNH10_00515

RST:	ATY39_16575

PAEK:

D3873_02415

PANC:

E2636_13785

PLAY:

DNR44_007425

VIJ:	JNUCC6_17325

UTH:	DKZ56_04625

NTR:	B0W44_13830

TVU:	AB849_010865

PABS:

JIR001_25190(ywfI)

LLD:	P620_14720

LCT:	BI355_0138

CMIC:

caldi_00530(ywfI)

TMR:

Tmar_0490

THEP:

DYI95_002200

TCP:	Q5761_02275

SAY:

TPY_1863

SAP:	Sulac_2065

STHR:

BXT84_12060

HFV:

R50_1549

VPR:

Vpar_0219

VAT:	B7L28_08440

VRM:	44547418_00240

VDN:	NCTC11831_00206

VNK:	VEIT17_02090

VRG:	OKW85_01175

LPIL:

LIP_0706

ERZ:	ER308_00365

EUZ:	DVS28_a2822

MTU:

Rv2676c

MTV:	RVBD_2676c

MTC:

MT2750

MRA:

MRA_2704

MTF:	TBFG_12691

MTB:	TBMG_01297

MTK:	TBSG_01308

MTZ:	TBXG_001288

MTG:	MRGA327_16430

MTI:	MRGA423_16640

MTE:	CCDC5079_2459

MTUR:

CFBS_2828

MTL:	CCDC5180_2429

MTO:	MTCTRI2_2728

MTD:

UDA_2676c

MTN:	ERDMAN_2938

MTJ:	J112_14340

MTUB:

MT7199_2708

MTUC:

J113_18615

MTUE:

J114_14285

MTX:	M943_13840

MTUH:

I917_18795

MTUL:

TBHG_02612

MTUT:

HKBT1_2819

MTUU:

HKBT2_2822

MTQ:	HKBS1_2826

MBO:	BQ2027_MB2695C

MBB:

BCG_2689c

MBT:

JTY_2683

MBM:	BCGMEX_2682c

MBK:	K60_027680

MBX:

BCGT_2508

MAF:

MAF_26800

MMIC:

RN08_2960

MCE:	MCAN_27021

MCQ:	BN44_60127

MCV:	BN43_40348

MCX:	BN42_40650

MCZ:	BN45_51055

MORY:

MO_002797(hemQ)

MLE:

ML1045

MLB:

MLBr01045

MPA:

MAP_2797c

MAO:

MAP4_1015

MAVI:

RC58_04995

MAVU:

RE97_04990

MAV:

MAV_3571

MIT:

OCO_34020

MIA:

OCU_34040

MID:

MIP_05124

MYO:

OEM_34400

MCHI:

AN480_18025

MIR:

OCQ_35240

MMAL:

CKJ54_15900

MLP:

MLM_1546

MMAN:

MMAN_03970

MSA:	Mycsm_02634

MUL:

MUL_3310

MMI:

MMAR_2040

MMAE:

MMARE11_19640

MLI:	MULP_02214

MPSE:

MPSD_20660

MSHO:

MSHO_51430

MMC:

Mmcs_2214

MKM:

Mkms_2260

MJL:

Mjls_2203

MMM:

W7S_17015

MKN:	MKAN_25530

MYV:	G155_13100

MYE:	AB431_12020

MHAD:

B586_14395

MDX:	BTO20_21220

MSHG:

MSG_01852

MFJ:	MFLOJ_13970

MSTO:

MSTO_15470

MSIM:

MSIM_04770

MSAK:

MSAS_56540

MKU:	I2456_10030

MLW:	MJO58_10035

MXE:	MYXE_30920

MNV:	MNVI_34610

MPAG:

C0J29_11625

MNM:	MNVM_36260

MGOR:

H0P51_11195

MCOO:

MCOO_02760

MBAI:

MB901379_01861

MSEO:

MSEO_06530

MHEK:

JMUB5695_03080

MGAU:

MGALJ_09480

MLJ:	MLAC_26090

MBRD:

MBRA_44960

MSHJ:

MSHI_20320

MMAM:

K3U93_09055

MSPG:

F6B93_08310

MOT:	LTS72_14525

MLM:	MLPF_2054(cld)

MPAA:

MKK62_15015

MMEH:

M5I08_18215

MKY:	IWGMT90018_38000

MADI:

A7U43_18510

MWU:	PT015_02850

MSM:	MSMEG_2782

MSG:	MSMEI_2713

MSB:	LJ00_13830

MSN:	LI99_13835

MSH:	LI98_13840

MVA:

Mvan_2483

MGI:

Mflv_3917

MSP:	Mspyr1_32620

MCB:	Mycch_2182

MNE:	D174_12190

MYN:	MyAD_11970

MFT:	XA26_26930

MPHL:

MPHLCCUG_03080(cld)

MVQ:

MYVA_2376

MLL:	B1R94_17090

MRH:	MycrhN_5538

MTHN:

4412656_02702

MHAS:

MHAS_02314

MDU:	MDUV_20870

MCHT:

MCHIJ_43470

MDR:	MDOR_15650

MAUU:

NCTC10437_02324

MMAG:

MMAD_23790

MMOR:

MMOR_39750

MFX:	MFAL_04880

MAIC:

MAIC_20970

MIJ:	MINS_22850

MALV:

MALV_12230

MTY:	MTOK_42160

MPSC:

MPSYJ_41970

MARZ:

MARA_15890

MGAD:

MGAD_14450

MHEV:

MHEL_45930

MSAR:

MSAR_33870

MANY:

MANY_07440

MAUB:

MAUB_57020

MPOF:

MPOR_27960

MPHU:

MPHO_11860

MMUC:

C1S78_012330

MMAT:

MMAGJ_58360

MBOK:

MBOE_47940

MFG:	K6L26_19130

MSEI:

MSEDJ_36090

MFLV:

NCTC10271_03055

MCEE:

MCEL_12970

MBRM:

L2Z93_002289

MMON:

EWR22_11260

MGO:	AFA91_25575

MHOL:

K3U96_15390

MSEN:

K3U95_10600

MPAE:

K0O64_11690

MRF:	MJO55_11190

MDF:	K0O62_12520

MCRO:

MI149_12555

MGRO:

FZ046_17265

MKR:	MKOR_14950

MPAK:

MIU77_11580

MAB:

MAB_2984c

MMV:	MYCMA_1646

MABB:

MASS_2919

MABL:

MMASJCM_2983

MCHE:

BB28_14995

MIZ:	BAB75_16045

MSTE:

MSTE_02949

MSAO:

MYCSP_13470

MSAL:

DSM43276_02764

MJD:	JDM601_2422

MTER:

4434518_02354

MMIN:

MMIN_01280

MHIB:

MHIB_18720

MHER:

K3U94_13735

MVM:	MJO54_13880

ASD:

AS9A_1782

CGL:	Cgl1899(Cgl1899)

CGB:

cg2079

CGU:

WA5_1824

CGT:

cgR_1728

CGS:	C624_09170

CGG:	C629_09180

CGM:

cgp_2079

CGJ:

AR0_08935

CGQ:	CGLAR1_08785

CGX:	SB89_08625

CEF:

CE1792

CDI:

DIP1394

CDP:	CD241_1339

CDH:	CDB402_1305

CDT:	CDHC01_1338

CDE:	CDHC02_1295

CDR:	CDHC03_1316

CDA:	CDHC04_1316

CDZ:	CD31A_1411

CDB:	CDBH8_1388

CDS:	CDC7B_1398

CDD:	CDCE8392_1312

CDW:	CDPW8_1384

CDV:	CDVA01_1279

CDIP:

ERS451417_01417

CJK:

jk1073

CUR:

cu0042

CUA:	CU7111_0041

CAR:	cauri_1441

CKP:	ckrop_1047

CPU:	CPFRC_06045

CPL:	Cp3995_1222

CPG:	CP316_06205

CPP:	CpP54B96_1216

CPK:	CP1002_07100

CPQ:	CPC231_06050

CPX:	CPI19_05470

CPZ:	CpPAT10_1191

COR:	Cp267_1250

COP:	CP31_06435

COD:	Cp106_1175

COS:	Cp4202_1185

COI:	CPCIP5297_06220

COE:	CP258_06220

COU:	CP162_05085

CPSE:

CPTA_01771

CPSU:

CPTB_01992

CPSF:

CPTC_01762

CRD:

CRES_1489

CUL:	CULC22_01306

CUC:	CULC809_01292

CUE:	CULC0102_1421

CUN:	Cul210932_1372

CUQ:	Cul210931_1264

CUZ:	Cul05146_1338

CUJ:	CUL131002_1293c

CUS:	CulFRC11_1280

CVA:

CVAR_1566

CHN:	A605_08185

CCN:	H924_07940

CTER:

A606_06215

CMD:	B841_07510

CAZ:	CARG_05525

CFN:	CFAL_06015

CCG:	CCASEI_06660

CVT:	B843_07850

CGY:	CGLY_08075

CAX:	CATYP_04545

CII:	CIMIT_07120

CUV:	CUREI_06920

COA:

DR71_2112

CDO:	CDOO_08310

CHM:	B842_07515

CSX:	CSING_07885

CMQ:	B840_07155

CKU:	UL82_05975

CCJ:	UL81_06770

CMV:	CMUST_08885

CEI:	CEPID_07225

CTED:

CTEST_07585

CUT:	CUTER_06325

CLW:	CLAC_05755

CDX:	CDES_08480

CSP:

WM42_2538

CSTA:

CSTAT_05955

CCJZ:

ccrud_08175

CFK:	CFRA_04985

CPHO:

CPHO_05320

CFC:	CFLV_07095

CGV:	CGLAU_07155

CSTR:

CBE89_06360

CAQU:

CAQU_07200

CSPH:

CSPHI_05955

CAMG:

CAMM_06150

CMIN:

NCTC10288_01060

CPEG:

CPELA_04840

CXE:	FOB82_11610

CEE:	CENDO_06480

CSAN:

E3227_08620

CGK:	CGERO_06330

CRF:	FRC0190_01430

CRL:	NCTC7448_02051

CCHO:

CCHOA_06650

CPRE:

Csp1_12840

CPSO:

CPPEL_05045

CSUR:

N24_1968

CCYS:

SAMEA4530656_0950

CMAT:

HBA49_01090

CYZ:	C3B44_04890

CKF:	I6I12_05965

CANS:

GP473_04950

CLIA:

C3E79_06340

CPRP:

I6I69_00600

CAMC:

I6I65_01975

CGLU:

I6J20_02890

CUO:	CUROG_05490

CLIZ:

G7Y31_06940

CSIL:

CBE74_07045

CTUB:

I6I74_00245

CLUJ:

IAU68_06645

CQN:	G7Y29_06180

CKW:	CKALI_06560

CCOE:

CETAM_07570

COK:	COCCU_08225

CZO:	IAU67_02505

CORY:

FQV43_05805

CMF:	GWO64_005320

CWK:	IA203_07260

CUW:	LH390_06520

CPOY:

GP475_06640

CACC:

CACC_07155(cld)

CFY:	I6L56_02060

CPSL:

KBP54_06520

CHIN:

J5O04_07390

CJH:	CJEDD_07285

CPSP:

L9H27_05995

CMAS:

CMASS_06030

CHEI:

CHEID_05585

CIHU:

CIHUM_06460

CCOY:

CCOY_07190

CHAD:

CHAD_07005

CFG:	CFREI_07830

CAQM:

CAQUA_05025

CCAW:

CCANI_08155

CAUI:

CAURIS_06505

CFAC:

CFAEC_08045

CFOU:

CFOUR_06515

CFEU:

CFELI_07850

CAUS:

CAURIC_07625

CATR:

CATRI_07485

CDUR:

CDUR_07475

CCOU:

CCONF_06785

CHAN:

CHAN_06290

CAFE:

CAFEL_06395

CGF:	CGUA_07415

CGOI:

CGOTT_06730

CAPP:

CAPP_06860

CBOV:

CBOVI_05025

CSUE:

QP029_11845

CBRE:

QP027_06275

CPYR:

CYJ47_05285(hemQ)

CRIE:

AK829_02695

BFV:	C628_09130

NFA:

NFA_37360

NFR:	ERS450000_00164

NCY:	NOCYR_3628

NBR:	O3I_029315

NNO:	NONO_c52570

NSL:	BOX37_20285

NSR:	NS506_05836

NTP:	CRH09_24385

NOZ:	DMB37_08190

NOD:	FOH10_18550

NAH:	F5544_29305

NAD:	NCTC11293_05101

NWL:	NWFMUON74_25430

NIE:	KV110_28430

NTC:	KHQ06_30370

NHU:	H0264_29320

NYA:	LTV02_04690

NGP:	LTT66_24840

NSPU:

IFM12276_18320

NYU:	D7D52_23020

RHA:	RHA1_ro06860

RER:

RER_28490

REY:

O5Y_13125

REB:	XU06_13345

RQI:	C1M55_14355

ROP:

ROP_68450

ROA:	Pd630_LPD03485

RPY:	Y013_01955

RBY:	CEJ39_12650

RHB:

NY08_1199

RAV:	AAT18_12340

RFA:	A3L23_04444(cld)

RHS:	A3Q41_03823(cld)

RHW:	BFN03_06615

RRZ:	CS378_02110

RHU:	A3Q40_01541

RHQ:	IM25_15940

RHOD:

AOT96_24565

RRT:	4535765_02093

RCR:	NCTC10994_00771

RTM:	G4H71_20495

RKO:	JWS14_36970

RGO:	KYT97_01800

ROZ:	CBI38_17015

RPSK:

JWS13_07225

RGOR:

NMQ04_09265

RANT:

RHODO2019_05670

RHOP:

D8W71_16130

REQ:

REQ_20610

WHR:	OG579_01490

GBR:

Gbro_2265

GPO:	GPOL_c21600

GOR:

KTR9_2182

GOQ:	ACH46_09410

GTA:	BCM27_11675

GOC:	CXX93_13445

GIT:	C6V83_09840

GRU:	GCWB2_14010

GOM:	D7316_00786

GAV:	C5O27_14080

GOD:	GKZ92_12880

GAM:	GII34_10535

GPD:	GII33_10090

GJI:	H1R19_10875

GOI:	LK459_22570

GHN:	MVF96_11065

GAMI:

IHQ52_16615

GMG:	NWF22_21390

GSI:	P5P27_08485

SPIN:

KV203_07855

TPR:

Tpau_1894

TSM:	ASU32_10165

TPUL:

TPB0596_26990

TSD:	MTP03_20910

SRT:

Srot_1917

DTM:	BJL86_1777

DIT:	C3V38_14540

DIZ:	CT688_08695

DPC:	A6048_08930

DLU:	A6035_08485

DKN:	NHB83_08295

TOY:	FO059_09945

SCO:	SCO6042(SC1B5.02)

SALB:

XNR_0758

SMA:	SAVERM_2221

SGR:

SGR_1469

SGB:

WQO_27895

SFI:

SFUL_5998

SANL:

KZO11_29970

SGRF:

SGFS_034320

SCYE:

R2B67_06035(hemQ)

SCB:	SCAB_20801

SSX:	SACTE_5263

SVL:	Strvi_2308

SHY:

SHJG_7102

SHO:	SHJGH_6862

SRC:	M271_14275

SMAL:

SMALA_5901

SSOI:

I1A49_33345

SFA:

Sfla_1209

SBH:

SBI_03081

SVE:

SVEN_5833

SDV:	BN159_2384

SALS:

SLNWT_0795

STRP:

F750_5626(hemQ)

SCI:	B446_28305

SLV:	SLIV_07930

SGU:	SGLAU_25835

SVT:	SVTN_29210

STRE:

GZL_02778

SCW:	TU94_25810

SLD:

T261_2027

SLC:	SL103_26115

SXI:	SXIM_46570

STRM:

M444_26530

STRC:

AA958_27870

SAMB:

SAM23877_5756

SPRI:

SPRI_1781

SCZ:	ABE83_06350

SCX:	AS200_12275

SRW:	TUE45_06648

STRF:

ASR50_27480

SLE:	sle_16390(sle_16390)

SRN:	A4G23_04651

SPAV:

Spa2297_25415

STRT:

A8713_25135

SCLF:

BB341_04660

SGS:	AVL59_11730

STSI:

A4E84_30960

SKY:	D0C37_05150

SALW:

CP975_28050

SGM:	GCM10017557_18100

SCAD:

DN051_10745

SPHW:

NFX46_09680

SLS:	SLINC_6446

SNR:	SNOUR_11900

SALU:

DC74_6073

SALL:

SAZ_31330

SPLU:

LK06_026525

STRD:

NI25_09165

SNW:	BBN63_06600

SAUO:

BV401_33410

SSIA:

A7J05_08840

SVU:	B1H20_28605

SPUN:

BFF78_10950

SGV:	B1H19_30550

SLAU:

SLA_5907

SALF:

SMD44_06640

SALJ:

SMD11_1529

SLX:	SLAV_09885(cld)

STRO:

STRMOE7_29535

SFK:

KY5_6206

SNZ:	DC008_27045

SGE:	DWG14_02079

SRJ:

SRO_1767

SLK:	SLUN_30695

SDX:	C4B68_09315

SGD:	ELQ87_09020

SQZ:	FQU76_27020

SCYA:

EJ357_35725

SAST:

CD934_06370

SNQ:	CP978_03140 CP978_26100

STIR:

DDW44_24475

SKA:	CP970_10005

SGZ:	C0216_08985

SVN:	CP980_07625

SNK:	CP967_05800

SHAW:

CEB94_31560

SRK:	FGW37_25435

SFIC:

EIZ62_06650

SGAL:

CP966_28160

SSPO:

DDQ41_26115

SVR:	CP971_09595

SPAD:

DVK44_28435

SFY:	GFH48_11135

SAQU:

EJC51_36025

SGF:	HEP81_01951

SCAV:

CVT27_27385

SSEO:

D0Z67_23020

SBY:	H7H31_06440

SRIM:

CP984_08630

SSUB:

CP968_08215

SPHV:

F9278_37685

SCIN:

CP977_26635

SFUG:

CNQ36_25720

SPAC:

B1H29_08530

STSU:

B7R87_27475

SCHA:

CP983_10310

SGX:	H4W23_30295

SCOE:

CP976_33310

SBAT:

G4Z16_05875

SSPB:

CP982_31765

SNF:	JYK04_06426

SPLA:

CP981_29685

SBRO:

GQF42_32660

STUI:

GCM10017668_55250

SATA:

C5746_32340

SCHF:

IPT68_28335

SHUN:

DWB77_01841

SHAR:

HUT13_23325

SCYG:

S1361_30205

SFEU:

IM697_33020

SLIA:

HA039_06960

SDW:	K7C20_28530

SVD:	CP969_29190

SCAL:

I6J39_28455

SAUH:

SU9_027255

SFB:	CP974_24940

SMOB:

J7W19_25030

SPRA:

CP972_28165

SPEU:

CGZ69_28810

SROI:

IAG44_09015

SXN:	IAG42_08010

SGJ:	IAG43_25995

SHK:	J2N69_29340

SANU:

K7396_08535

STRY:

EQG64_28615

SDD:	D9753_07795

SACT:

DMT42_29685

SMAO:

CAG99_03565

SGOB:

test1122_22240

SINE:

KI385_33990

SLF:	JEQ17_12570

SDEC:

L3078_35215

SAOV:

G3H79_07715

SDUR:

M4V62_11370

SYAN:

NRK68_26735

SRUG:

F0345_23920

SAKB:

K1J60_10745

STAA:

LDH80_10085

SNIG:

HEK616_50540

SVIO:

HWN34_04475

SCAE:

IHE65_10280

STUB:

MMF93_26185

SSPN:

LXH13_30220

SCIR:

STRCI_006202

SXT:	KPP03845_105695

SLON:

LGI35_32920

SDRZ:

NEH16_05765

STUD:

STRTU_001541

STEE:

F3L20_12400

SENG:

OJ254_30000

SGK:	PET44_25090

SANT:

QR300_12070

SYUN:

MOV08_11720

SARG:

HKX69_07565

SJN:	RI060_09335(hemQ)

SCYN:

N8I84_30325

SOV:	QZH56_06725

SFIY:

F0344_05505

SHAU:

K9S39_12610

SKG:	KJK29_07445

SCOA:

QU709_09280

SLAI:

P8A22_07865

SROC:

RGF97_05785

SFP:	QUY26_08395

SCHG:

NRO40_23575

STTN:

BSL84_26165

SINN:

ABB07_08250

STRZ:

OYE22_06245

SCT:

SCAT_4690

SCY:	SCATT_46820

KSK:

KSE_55140

KAB:	B7C62_29790

KAU:	B6264_04675

KIT:	CFP65_5401

KIS:	HUT16_25695

STRI:

C7M71_023315

YIA:	LO772_09425

STRH:

GXP74_31400

ABRY:

NYE86_25175

AGLA:

OIE69_11915

LXL:	KDY119_02678(hemH)

PSIC:

J4E96_04100

LEU:	Leucomu_07520

LTR:	EVS81_00325

LLUT:

K1X41_01060

LARI:

KI794_11720

LALL:

MUN78_07515

LRP:	MUN76_02400

LTN:	KVY00_01435

ACIT:

HPK19_17270

ACAO:

NF551_11995

AZH:	MUK71_11945

AGEG:

MUG94_12925

AKO:	N9A08_11485

AZX:	N2K95_11905

AJR:	N2K98_12560

BCV:

Bcav_1089

JDE:

Jden_1885

KSE:	Ksed_15650

DNI:	HX89_06575

DAY:	FV141_05930

DERM:

H7F30_11615

LMOI:

VV02_16225

YIM:	J5M86_08510

ALX:	LVQ62_10930

BEI:	GCM100_15100

XCE:

Xcel_2623

XYL:	ET495_09405

XYA:	ET471_01920

IVA:	Isova_2452

IDO:

I598_3284

CET:	B8281_08605

CCEU:

CBR64_02675

CPRT:

FIC82_007455

SKE:	Sked_08350

CFL:

Cfla_2406

CFI:

Celf_1281

CGA:	Celgi_1049

CEZ:	CBP52_08225

CELZ:

E5225_05605

CEJ:	GC089_05865

CELH:

GXP71_09920

CIRA:

LFM56_06030

CPAL:

F1D97_14880

CELC:

K5O09_13515

CDON:

KKR89_12030

CWAN:

KG103_12125

CFEN:

KG102_12185

CWN:	NP075_12580

CCHE:

NP064_12300

CXIE:

NP048_12165

OEK:	FFI11_018330

PSEK:

GCM125_21000

ICA:	Intca_1906

ARS:	ADJ73_11665

JTE:	ASJ30_06975

JLI:	EXU32_07625

JME:	EEW87_008165

JAY:	H7A72_07030

JCR:	O9K63_04100

TEH:	GKE56_06030

PHW:	G7075_05785

PEI:	H9L10_06530

TED:	U5C87_15415(hemQ)

SERJ:

SGUI_0519

SERW:

FY030_06365

ORN:	DV701_03580

ORZ:	FNH13_09515

ORD:	L0A91_05105

OCP:	NF557_07315

BLY:	A2T55_10420

BLIN:

BLSMQ_2298

BRI:	FDF13_12370

BLUT:

EW640_02190

BCAU:

I6G59_13950

BSPO:

L1F31_10645

DCO:	SAMEA4475696_1613

AUS:	IPK37_18610

GEZ:	FE251_06780

GYU:	FE374_17985

ARUB:

J5A65_06590

MPH:

MLP_23160

MIK:	FOE78_12615

MICG:

GJV80_08825

TLA:	TLA_TLA_02756

RAIN:

Rai3103_15170

BROO:

brsh051_18310

NCA:

Noca_3671

NDK:

I601_0385

NOY:	EXE57_07840

NOI:	FCL41_02985

NOO:	FE634_15565

NDP:	E2C04_03710

NSN:	EXE58_12160

NBE:	Back2_22300

NANO:

G5V58_01450

NMES:

H9L09_18510

NARO:

CFH99_06045

NPI:	G7071_01495

NAQU:

ENKNEFLB_03811

NRO:	K8W59_03295

NOQ:	LN652_09150

NCQ:	K6T13_03530

NPC:	KUV85_16995

NPS:	KRR39_06020

NMAR:

HPC71_04260

NFC:	KG111_03400

PSIM:

KR76_21680

AER:	AERYTH_10090

AEZ:	C3E78_10635

AEB:	C6I20_09405

AEF:	GEV26_10515

ASEZ:

H9L21_06500

ADB:	NP095_06485

AWN:	NQV15_10490

MUZ:	H4N58_08500

SGRG:

L0C25_19860

NBT:	KLP28_15585

KFL:

Kfla_3727

KQI:	F1D05_36995

KSL:	OG809_29350

TFU:

Tfu_1896

THAO:

NI17_011615

TALX:

FOF52_09130

NDA:

Ndas_2827

NAL:

B005_5371

NGV:	CDO52_17910

NEX:	NE857_20355

NEC:	KGD82_10720

NAKE:

KGD83_11435

NCG:	KGD84_11255

STRR:

EKD16_14575

SNAH:

OUQ99_10210

SAIU:

J4H86_00755

TCU:

Tcur_1766

ACTW:

F7P10_05595

AGRA:

AGRA3207_001283

AMAZ:

LUW76_10135

ACIR:

OG979_31370

SPIQ:

OHA34_10820

ACTQ:

OG417_38605

SRO:

Sros_6718

NOA:	BKM31_01165

NOW:	GBF35_36875

NCX:	Nocox_29950

NGN:	LCN96_41140

NFS:	OIE67_07840

TBI:

Tbis_2261

MHAI:

OHB01_37680

NAKA:

H7F38_21410

GOB:

Gobs_1891

BSD:	BLASA_3273

BLAP:

MVA48_01380

MMAR:

MODMU_3905

KRA:

Krad_1587

SEN:

SACE_1838

SACG:

FDZ84_21520

SVI:	Svir_24070

SACC:

EYD13_13440(cld)

AMD:

AMED_2645

AMN:

RAM_13445

AMM:

AMES_2617

AMZ:

B737_2618

AOI:

AORI_2632

AJA:	AJAP_25670

AMQ:	AMETH_4743

AMYC:

CU254_11085

AMYB:

BKN51_05785

AAB:	A4R43_13820

AMYY:

YIM_30985

AORI:

SD37_14255

AACD:

LWP59_28630

APRT:

MUY14_23145

AROO:

NQK81_08945

ATHM:

L1857_26485

ARHD:

VSH64_02570(hemQ)

PDX:

Psed_2896

PSEA:

WY02_27715

PSEE:

FRP1_15030

PSEH:

XF36_15250

PSEQ:

AD006_22695

PECQ:

AD017_02280

PHH:	AFB00_00260

PAUT:

Pdca_41780

PBRO:

HOP40_29885

PPEL:

H6H00_26995

APRE:

CNX65_07720

AMI:

Amir_1554

SESP:

BN6_18640

SSYI:

EKG83_09100

KAL:

KALB_6806

KUT:	JJ691_98080

KBU:	Q4V64_39950

KPHY:

AOZ06_14845

LED:	BBK82_01020

AHM:	TL08_20570

ACTI:

UA75_24215

ACAD:

UA74_23710

AHG:	AHOG_21590

ACTA:

C1701_04720

ALO:

CRK55877

PMAD:

BAY61_11315

SACE:

GIY23_08220

ACTU:

Actkin_01730

CROS:

N8J89_10860

ACTY:

OG774_09410

UME:	RM788_37200(hemQ)

STP:	Strop_1534

SAQ:

Sare_1476

MAU:	Micau_1629

MIL:

ML5_1888

MICB:

MicB006_1653

MTUA:

CSH63_16135

MICH:

FJK98_08505

MTEM:

GCE86_02335

MCAB:

HXZ27_09420

MSAG:

GCM10017556_41740

VMA:	VAB18032_12740

MCRA:

ID554_04015

VER:	HUT12_08990

MENO:

Jiend_11460

MCHL:

PVK74_29365

MFEU:

H1D33_14955

MPRN:

Q3V37_30010

MHAW:

RMN56_03210(hemQ)

ASE:

ACPL_7084

AMS:	AMIS_68280

ACTN:

L083_6661

AFS:

AFR_35165

ACTS:

ACWT_6953

AIH:	Aiant_29010

ACTR:

Asp14428_64010

ACTL:

L3i22_094030

ASIC:

Q0Z83_101780

AOU:	ACTOB_007371

PLK:	CIK06_08330

PLAB:

C6361_15040

PLAT:

C6W10_15310

PFLA:

Pflav_089020

PSUU:

Psuf_052070

ATL:	Athai_34420

ASER:

Asera_40340

PRY:	Prubr_42290

CATI:

CS0771_25620

DVC:	Dvina_09400

DFU:	Dfulv_08830

DROS:

Drose_09015

DAUR:

Daura_08820

DMAT:

Dmats_08920

NHY:	JQS43_07685

CCAZ:

COUCH_09135

CAI:

Caci_6785

SNA:

Snas_3926

NAV:	JQS30_05720

GLY:	K3N28_17435

AWL:	P8A24_00340

TPEC:

HLG82_09645

WNE:	PIG85_10325

VCB:	CYK25_010575

BAST:

BAST_0811

AEY:	CDG81_15750

JTL:	M6D93_10215

ABAI:

IMCC26256_11285

AFO:

Afer_1843

AYM:	YM304_04960

ATQ:	GH723_15810

AQZ:	KSP35_12025

IAM:	HC251_03885

DHI:	LH044_14775

TTH:	TT_C1352(curD)

TTJ:	TTHA1714(TTHA1714)

TTS:	Ththe16_1731

TTL:	TtJL18_0330

TSC:	TSC_c02510

THC:	TCCBUS3UF1_20310

TOS:	Theos_0057

TAQ:

TO73_0150

TPAR:

AV541_02185

TBC:	A0O31_01283

TANT:

KNN15_05465

VAB:

WPS_05530

ROO:	G5S37_01735

LUO:	HHL09_18680

LAMB:

KBB96_11785

SOA:	G3M56_007800

VEG:	SAMN05444156_1993

FPES:

NXS98_04620

XII:	AMD24_00296

MIN:	Minf_0914(ywfI)

MKC:

kam1_945

MFH:	MFUM_1107(ywfI)

MCAO:

IT6_02050

MEAP:

MTHMO_0945(ywfI)

RBA:

RB10088

PSL:

Psta_0500

PIR:	VN12_21815

RUL:

UC8_30990

RML:	FF011L_28290

MFF:	MFFC18_36880

ROL:	CA51_16620

RUV:

EC9_17110

AHEL:

Q31a_27770

LCRE:

Pla8534_34670

AAGG:

ETAA8_34250

BVO:	Pan97_32450

BREM:

PSR63_22225

RLC:	K227x_42170

SMAM:

Mal15_08820

SNEP:

Enr13x_64260

TTF:

THTE_3205

LPAV:

PLANPX_1976

LLH:

I41_18120

AMUC:

Pan181_18450

PND:	Pla175_33390

AMOB:

HG15A2_19530

BMEI:

Spa11_17150

PLM:

Plim_3790

PEH:	Spb1_03670

PBS:	Plabr_0183

PLS:	VT03_27570

PLH:	VT85_16120

FMR:	Fuma_03866

GMR:	GmarT_28820

GIM:	F1728_00475

GPN:	Pan110_27730

GFM:	Enr17x_30080

MRI:	Mal4_10210

SDYN:

Mal52_40160

PLON:

Pla110_22950

ACAF:

CA12_34750

SVP:	Pan189_23020

TPOL:

Mal48_39610

CHYA:

V22_23620

CCOS:

Pan44_33460

PVAR:

SH412_005518

CCOP:

Mal65_42000

IPA:

Isop_0903

SACI:

Sinac_2594

PBOR:

BSF38_04551

AGV:	OJF2_61070

ABA:	Acid345_1955

ACA:

ACP_0819

GRW:	FTO74_08745

GRB:	GOB94_15625

TALB:

FTW19_20935

ABAS:

ACPOL_2493

ADIN:

H7849_07010

ORP:	MOP44_17845

SUS:

Acid_0345

PFER:

IRI77_25065

ABAC:

LuPra_03258

GBA:

J421_3680

HAL:

VNG_2021C

HSL:	OE_3832F(hemQ)

HANR:

LJ422_08125

HDL:	HALDL1_15020

HHB:	Hhub_3323(hemQ)

HAGS:

JT689_09475

HABO:

JRZ79_07860

HNO:	LT974_13435

HLU:	LT972_01345

HALH:

HTSR_1774

HHSR:

HSR6_1840

HSU:	HLASF_1969

HSF:	HLASA_1955

HAHS:

HSRCO_2607(ywfI)

SALR:

FQU85_06030

HALR:

EFA46_002595

HJE:	HacjB3_04330

HDO:	MUK72_00650

HALX:

M0R89_04325

HAXZ:

M0R88_04385

HAYC:

NGM10_10690

HAXY:

NGM07_09725

SALI:

L593_03925

SAIM:

K0C01_07570 K0C01_11015

HARA:

AArcS_0406(ywfI)

HMA:

rrnAC3100

HHI:

HAH_0351

HHN:	HISP_01840

HAB:	SG26_09650

HTA:	BVU17_01680

HALJ:

G9465_01025

HSIN:

KDQ40_11925

NPH:	NP_2262A(hemQ)

NMO:	Nmlp_1161(hemQ)

NHO:	HWV23_13550

NSAL:

HWV07_07400

HUT:

Huta_1222

HTI:

HTIA_1138

HALA:

Hrd1104_02920

HASV:

SVXHr_0392(hemQ)

HABN:

HBNXHr_0377(hemQ)

HMU:

Hmuk_1250

HALZ:

E5139_09425

HALL:

LC1Hm_0437(ywfI)

HAZP:

GBQ70_09420

HALI:

BV210_11030

HSN:	DV733_01920

HDS:	HSR122_0255(ywfI)

HRR:	HZS55_05230

HPEL:

HZS54_05335

HLT:	I7X12_08040

HARC:

HARCEL1_08860

SSAI:

N0B31_10540

HAAD:

MW046_04995

HWA:	HQ_1094A(hemQ)

HWC:	Hqrw_1123(hemQ)

HVO:	HVO_1871(hemQ)

HME:

HFX_1953

HGI:	ABY42_09050

HALE:

G3A49_12355

HLS:	KU306_03270

HLN:	SVXHx_2746(hemq)

HBO:	Hbor_04740

HAQ:	DU484_03585

HAJ:	DU500_04070

HAER:

DU502_01740

HRA:	EI982_11655

HLM:	DV707_14565

HALM:

FCF25_01060

HLA:

Hlac_2193

HALP:

DOS48_10455

HALB:

EKH57_14015

HEZZ:

EO776_12365

HALQ:

Hrr1229_011170

HSS:	J7656_03955

HSAI:

HPS36_09290

HAZZ:

KI388_10905

HAE:	halTADL_0324 halTADL_1349

HALN:

B4589_011930

HALG:

HUG10_10510

HALU:

HUG12_05360

HMP:	K6T50_07675

HRE:	K6T36_07495

HRM:	K6T25_08300

HACB:

Hbl1158_14060

HDF:	AArcSl_2750

HAH:	Halar_2702

HTU:

Htur_3475

HSAL:

JMJ58_10985

HAKZ:

J0X25_05090

NMG:	Nmag_1506(hemQ)

HXA:	Halxa_3477

NAT:

NJ7G_2646

NPE:	Natpe_0437

NVR:	FEJ81_02450

NPL:	FGF80_09370

NAY:	HYG81_08510

HALY:

HYG82_11475

HJT:	DVR14_11480

HLO:	J0X27_05735

NGE:	Natgr_2412

HRU:	Halru_2776

SAWL:

NGM29_00915

HALV:

NGM15_10520

NOU:	Natoc_2380

HLR:	HALLA_17850

HLC:	CHINAEXTREME07140

NAJ:	B1756_10560

NAG:	AArcMg_0396

NAN:	AArc1_0404

NARA:

QQ977_12220

NBG:	DV706_05055

NAS:	GCU68_08105

HDA:	BB347_15860

» show all

Reference

1 [PMID:20543190]

Authors

Dailey TA, Boynton TO, Albetel AN, Gerdes S, Johnson MK, Dailey HA

Title

Discovery and Characterization of HemQ: an essential heme biosynthetic pathway component.

Journal

J Biol Chem 285:25978-86 (2010)
DOI:10.1074/jbc.M110.142604

Reference

2 [PMID:26083961]

Authors

Celis AI, Streit BR, Moraski GC, Kant R, Lash TD, Lukat-Rodgers GS, Rodgers KR, DuBois JL

Title

Unusual Peroxide-Dependent, Heme-Transforming Reaction Catalyzed by HemQ.

Journal

Biochemistry 54:4022-32 (2015)
DOI:10.1021/acs.biochem.5b00492

Reference

3 [PMID:27758026]

Authors

Hofbauer S, Mlynek G, Milazzo L, Puhringer D, Maresch D, Schaffner I, Furtmuller PG, Smulevich G, Djinovic-Carugo K, Obinger C

Title

Hydrogen peroxide-mediated conversion of coproheme to heme b by HemQ-lessons from the first crystal structure and kinetic studies.

Journal

FEBS J 283:4386-4401 (2016)
DOI:10.1111/febs.13930

Sequence

[lmo:lmo2113]

Reference

4 [PMID:27936663]

Authors

Celis AI, Gauss GH, Streit BR, Shisler K, Moraski GC, Rodgers KR, Lukat-Rodgers GS, Peters JW, DuBois JL

Title

Structure-Based Mechanism for Oxidative Decarboxylation Reactions Mediated by Amino Acids and Heme Propionates in Coproheme Decarboxylase (HemQ).

Journal

J Am Chem Soc 139:1900-1911 (2017)
DOI:10.1021/jacs.6b11324

Sequence

[gse:GT50_08830]

Other DBs

ExplorEnz - The Enzyme Database:

1.3.98.5

IUBMB Enzyme Nomenclature:

1.3.98.5

ExPASy - ENZYME nomenclature database:

1.3.98.5

BRENDA, the Enzyme Database:

1.3.98.5

DBGET integrated database retrieval system