KEGG ENZYME: 1.3.99.33

ENZYME: 1.3.99.33

Entry

EC 1.3.99.33                Enzyme

Name

urocanate reductase;
urdA (gene name)

Class

Oxidoreductases;
Acting on the CH-CH group of donors;
With unknown physiological acceptors

Sysname

dihydrourocanate:acceptor oxidoreductase

Reaction(IUBMB)

dihydrourocanate + acceptor = urocanate + reduced acceptor [RN:R10330]

Reaction(KEGG)

R10330

Substrate

dihydrourocanate [CPD:C20522];
acceptor [CPD:C00028]

Product

urocanate [CPD:C00785];
reduced acceptor [CPD:C00030]

Comment

The enzyme from the bacterium Shewanella oneidensis MR-1 contains a noncovalently-bound FAD and a covalently-bound FMN. It functions as part of an anaerobic electron transfer chain that utilizes urocanate as the terminal electron acceptor. The activity has been demonstrated with the artificial donor reduced methyl viologen.

History

EC 1.3.99.33 created 2013

Pathway

ec00340

Histidine metabolism

Orthology

K17363

urocanate reductase

Genes

CAMA:

F384_13015

VGA:	BSQ33_13175

VSR:	Vspart_01796(urdA_2)

VZI:	G5S32_18720

VRU:	RND59_16215

SON:

SO_4620

SBM:	Shew185_4193

SBN:	Sbal195_4325

SBT:	Sbal678_4357

SPC:	Sputcn32_3795

SHP:	Sput200_0127

SSE:

Ssed_0694

SPL:

Spea_3574

SHN:	Shewana3_4004

SHW:	Sputw3181_0118

SHL:

Shal_2847

SWD:

Swoo_3912

SHF:	CEQ32_15300

SBJ:	CF168_20210

SHEW:

CKQ84_06850

SALG:

BS332_06385

SBK:	SHEWBE_1046(urdA)

SCAA:

TUM17387_37640(urdA)

SEUR:

FM038_021900

SXM:	MKD32_19840(urdA)

SHEJ:

MZ182_00600(urdA)

SCHK:

GII14_21340

SDEO:

D0436_21020(urdA)

SMES:

K0I73_17430

GAP:	GAPWK_0254

SUTT:

SUTMEG_10550(urdA_1) SUTMEG_12430(urdA_2)

SUTK:

FG381_11010

SWS:	I6J16_01760 I6J16_04100

BBAY:

A4V04_08680

BLR:	BRLA_c010270

BRW:	GOP56_21105

POD:	PODO_03480

PAEF:

R50345_03355

PAEJ:

H70737_03570

PLUT:

EI981_16270

PBAC:

HUB98_26735

PTHI:

NDS46_24555

PAMY:

P9222_27835

PDY:	QJQ58_27575

LPK:	LACPI_0686(fccA1)

LRN:	CMV25_10335

LCAR:

BHS00_07215

LPAA:

BHS01_08105

SMU:

SMU_180

SMC:	SmuNN2025_0152

SMUT:

SMUGS5_00790

SMJ:	SMULJ23_0173

SMUA:

SMUFR_0150(frdA)

SUB:

SUB0908

SGA:	GALLO_1929

SGG:	SGGBAA2069_c18810

SGT:

SGGB_1913

STK:

STP_0733

STB:

SGPB_1754

SCP:	HMPREF0833_10770

SCF:	Spaf_1344(frdA)

SMN:	SMA_1833(ifcA)

SIF:

Sinf_1644

STV:	V470_10250

SPAT:

A0O21_07025

SSOB:

DK181_06480

SRAT:

FY406_03685

STRG:

SRT_01730

SMEN:

SAMEA4412692_1366(fccA)

SCHJ:

DDV21_003160

SURN:

NCTC13766_01990(ifcA)

SRUM:

GPZ88_02940

LJO:

LJ_0051

LJF:	FI9785_114

LJH:

LJP_0059

LJN:	T285_00310

LAC:

LBA0064

LAD:

LA14_0068

LDB:

Ldb0125

LBU:

LBUL_0105

LDE:	LDBND_0097

LDL:

LBU_0089

LGA:

LGAS_0049

LHL:

LBHH_1321

LCR:	LCRIS_00618

LAM:	LA2_00360 LA2_04165

LAI:	LAC30SC_00280 LAC30SC_03955

LAY:	LAB52_00295 LAB52_03950

LKE:	WANG_0866 WANG_1634

LAW:	LACWKB8_0103

LAE:

LBAT_0078

LJE:	BUE77_00575

LAMY:

B1745_07375

LPW:	LpgJCM5343_00480(frdA)

LKL:	DKL58_00435

LAPI:

DKL56_00370

LTA:	H1A07_00270

LUU:	H4B44_00465

LPAI:

GYM71_00560

LMUL:

PUW59_00270

LXO:	KIM322_01390

LPL:

lp_1425

LPJ:

JDM1_1191

LPT:	zj316_1469

LPR:	LBP_cg1088

LPZ:

Lp16_1092

LPB:	SH83_05895

LPX:	ASU28_05785 ASU28_14090

LPG:	BB562_10265

LARG:

LPA65_05670 LPA65_15010

LFE:

LAF_0986

LFR:

LC40_0640

LFF:

LBFF_1078

LOR:	AYI71_14025

LGAS:

LG045_03685

LNG:	BSQ50_05310

LHW:	BSQ49_01200

LMAL:

LM596_01430

LCU:	PL11_000170

LSUA:

H3M12_06600

LAGL:

BEN83_08220

LACA:

LAC1533_0308

LPD:	AYR62_12100

LALW:

BTM29_03960

LALI:

LA20249_05385

LDX:	LH506_03660

ECAS:

ECBG_01227

EGA:	AL523_05475

EGV:	EGCR1_00865

EIE:	ENLAB_19170

VCP:	H9L18_02710

VHY:	G7082_08820

VFV:	K5K99_01000

VLU:	M2919_03380

VIE:	OL234_01845

AUR:	HMPREF9243_0557 HMPREF9243_1093

AUN:	AWM73_04395 AWM73_06760

AUI:	APT62_08825

ASAN:

AWM72_05045 AWM72_07150

ACG:	AWM71_07330

ALOY:

CJ190_004520 CJ190_006990

AMIT:

DBT49_0005160 DBT49_0007505

ATJ:	DBT50_000430 DBT50_003960

ADC:	FOC79_05320

ABAE:

CL176_04855 CL176_05320

IRU:	M0R79_04640

GSG:	CYJ72_006315

FCT:	NRE15_05745

CARN:

FPV25_03505

JEH:	EJN90_09320

DPM:	FNV33_02535

GAD:	K8O88_06940

CTC:

CTC_01847

CTET:

BN906_01988

CBE:

Cbei_2056

CBZ:

Cbs_2056

CBEI:

LF65_02225

CSR:	Cspa_c49690

CSB:	CLSA_c08970(urdA)

CDY:	F3K33_10220

CCOH:

SAMEA4530647_1605(ifcA_3)

CGAS:

J1C67_18130

CMAH:

C1I91_24555

CGEL:

psyc5s11_14890

CINT:

HZF06_03020

ALAC:

JYE50_02595

AHC:	JYE49_03305

CBAF:

JS518_06210

CPY:

Cphy_3885

LXA:	OW255_07785

ACHT:

bsdcttw_15800

AOE:

Clos_0178

TGC:	L0P85_07795

TEB:	T8CH_0717(urdA)

THYR:

P4S50_13520

NTH:	Nther_2466

APR:

Apre_0378

PMIC:

NW74_04630

TIZ:	RBU61_12865

BULL:

JOS54_05205

SMOE:

RGT18_05890(urdA_1) RGT18_09670(urdA_2)

CCU:	Ccur_10160

ELE:	Elen_0107 Elen_0488

EGD:	GS424_000585 GS424_002540 GS424_002840

AEQ:

AEQU_1715

CBAC:

JI75_00415 JI75_03430

BWA:	HLV38_00765 HLV38_05590

RTS:	CE91St31_14340(urdA)

CCYS:

SAMEA4530656_2667

GMN:	GMOLON4_1395(ifcA)

TPAV:

HRQ91_08135

TSK:	HRI97_04680 HRI97_12305

BHC:	JFL75_00380

FVA:	FV113G1_07820

FUL:	C4N20_02440

FMO:	C4N19_09130

FHO:	H9Q81_04415

IPO:	Ilyop_1577

CSOM:

MKD34_04885 MKD34_09760

» show all

Reference

1 [PMID:23078170]

Authors

Bogachev AV, Bertsova YV, Bloch DA, Verkhovsky MI

Title

Urocanate reductase: identification of a novel anaerobic respiratory pathway in Shewanella oneidensis MR-1.

Journal

Mol Microbiol 86:1452-63 (2012)
DOI:10.1111/mmi.12067

Sequence

[son:SO_4620]

Other DBs

ExplorEnz - The Enzyme Database:

1.3.99.33

IUBMB Enzyme Nomenclature:

1.3.99.33

ExPASy - ENZYME nomenclature database:

1.3.99.33

BRENDA, the Enzyme Database:

1.3.99.33

DBGET integrated database retrieval system