KEGG   ENZYME: 1.4.1.7
Entry
EC 1.4.1.7                  Enzyme                                 
Name
serine 2-dehydrogenase;
L-serine:NAD+ oxidoreductase (deaminating);
serine dehydrogenase
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With NAD+ or NADP+ as acceptor
Sysname
L-serine:NAD+ 2-oxidoreductase (deaminating)
Reaction(IUBMB)
L-serine + H2O + NAD+ = 3-hydroxypyruvate + NH3 + NADH + H+ [RN:R00581]
Reaction(KEGG)
R00581;
(other) R00145 R00146
Substrate
L-serine [CPD:C00065];
H2O [CPD:C00001];
NAD+ [CPD:C00003]
Product
3-hydroxypyruvate [CPD:C00168];
NH3 [CPD:C00014];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.4.1.7 created 1972, modified 2003
Reference
1  [PMID:5972761]
  Authors
Kretovich VL, Stepanovich KM.
  Title
[The enzyme catalyzing the reductive amination of oxypyruvate]
  Journal
Izv Akad Nauk SSSR Biol 2:295-300 (1966)
Other DBs
ExplorEnz - The Enzyme Database: 1.4.1.7
IUBMB Enzyme Nomenclature: 1.4.1.7
ExPASy - ENZYME nomenclature database: 1.4.1.7
BRENDA, the Enzyme Database: 1.4.1.7
CAS: 9038-55-5

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