Entry |
|
Name |
|
Class |
Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor
|
Sysname |
1,2-dihydrovomilenine:NADP+ oxidoreductase
|
Reaction(IUBMB) |
1,2-dihydrovomilenine + NADP+ = vomilenine + NADPH + H+ [RN: R05878]
|
Reaction(KEGG) |
|
Substrate |
|
Product |
|
Comment |
Forms part of the ajmaline biosynthesis pathway.
|
History |
EC 1.5.1.32 created 2002
|
Pathway |
ec00901 | Indole alkaloid biosynthesis |
ec01110 | Biosynthesis of secondary metabolites |
|
Reference |
|
Authors |
von Schumann G, Gao S, Stockigt J. |
Title |
Vomilenine reductase--a novel enzyme catalyzing a crucial step in the biosynthesis of the therapeutically applied antiarrhythmic alkaloid ajmaline. |
Journal |
|
Other DBs |
ExplorEnz - The Enzyme Database: | 1.5.1.32 |
ExPASy - ENZYME nomenclature database: | 1.5.1.32 |
|