| Entry |
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| Name |
2-methyl-1-pyrroline reductase;
(R)-imine reductase (ambiguous)
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| Class |
Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
(R)-2-methylpyrrolidine:NADP+ 2-oxidoreductase
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| Reaction(IUBMB) |
(R)-2-methylpyrrolidine + NADP+ = 2-methyl-1-pyrroline + NADPH + H+ [RN: R10730]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
The enzyme from the bacterium Streptomyces sp. GF3587 is highly specific for its substrate and forms only the (R) isomer.
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| History |
EC 1.5.1.48 created 2014
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| Orthology |
| K19809 | 2-methyl-1-pyrroline reductase |
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| Genes |
| STUI: | GCM10017668_54130(mmsB) |
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| Reference |
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| Authors |
Mitsukura K, Suzuki M, Shinoda S, Kuramoto T, Yoshida T, Nagasawa T |
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| Title |
Purification and characterization of a novel (R)-imine reductase from Streptomyces sp. GF3587. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 1.5.1.48 |
| ExPASy - ENZYME nomenclature database: | 1.5.1.48 |
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