| Entry |
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| Name |
D-proline dehydrogenase;
D-Pro DH;
D-Pro dehydrogenase;
dye-linked D-proline dehydrogenase
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| Class |
Oxidoreductases;
Acting on the CH-NH group of donors;
With unknown physiological acceptors
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| Sysname |
D-proline:acceptor oxidoreductase
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| Reaction(IUBMB) |
D-proline + acceptor = 1-pyrroline-2-carboxylate + reduced acceptor [RN: R09496]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
1-pyrroline-2-carboxylate [CPD: C03564];
reduced acceptor [CPD: C00030]
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| Comment |
A flavoprotein (FAD). The enzyme prefers D-proline and acts on other D-amino acids with lower efficiency.
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| History |
EC 1.5.99.13 created 2010, modified 2011
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| Pathway |
| ec00330 | Arginine and proline metabolism |
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| Orthology |
| K17851 | D-proline dehydrogenase |
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| Genes |
| TTN: | TTX_1315(dadA) TTX_1450 |
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| Reference |
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| Authors |
Tani Y, Tanaka K, Yabutani T, Mishima Y, Sakuraba H, Ohshima T, Motonaka J |
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| Title |
Development of a D-amino acids electrochemical sensor based on immobilization of thermostable D-proline dehydrogenase within agar gel membrane. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Satomura T, Kawakami R, Sakuraba H, Ohshima T |
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| Title |
Dye-linked D-proline dehydrogenase from hyperthermophilic archaeon Pyrobaculum islandicum is a novel FAD-dependent amino acid dehydrogenase. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 1.5.99.13 |
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