Entry
Name
nitrite dismutase;
Prolixin S;
Nitrophorin 7
Class
Oxidoreductases;
Acting on other nitrogenous compounds as donors;
With a nitrogenous group as acceptor
BRITE hierarchy
Sysname
nitrite:nitrite oxidoreductase
Reaction(IUBMB)
3 nitrite + 2 H+ = 2 nitric oxide + nitrate + H2O [RN:
R09751 ]
Reaction(KEGG)
Substrate
Product
Comment
Contains ferriheme b. The enzyme is one of the nitrophorins from the salivary gland of the blood-feeding insect Rhodnius prolixus. Nitric oxide produced induces vasodilation after injection. Nitrophorins 2 and 4 can also catalyse this reaction.
History
EC 1.7.6.1 created 2011
Orthology
Reference
Authors
He C, Knipp M
Title
Formation of nitric oxide from nitrite by the ferriheme b protein nitrophorin 7.
Journal
Sequence
Reference
Authors
He C, Ogata H, Knipp M
Title
Formation of the complex of nitrite with the ferriheme b beta-barrel proteins nitrophorin 4 and nitrophorin 7.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 1.7.6.1
ExPASy - ENZYME nomenclature database: 1.7.6.1
BRENDA, the Enzyme Database: 1.7.6.1