KEGG ENZYME: 1.8.2.5

ENZYME: 1.8.2.5

Entry

EC 1.8.2.5                  Enzyme

Name

thiosulfate reductase (cytochrome)

Class

Oxidoreductases;
Acting on a sulfur group of donors;
With a cytochrome as acceptor

Sysname

sulfite,hydrogen sulfide:ferricytochrome-c3 oxidoreductase (thiosulfate-forming)

Reaction(IUBMB)

sulfite + hydrogen sulfide + 2 ferricytochrome c3 = thiosulfate + 2 ferrocytochrome c3 [RN:R11606]

Reaction(KEGG)

R11606

Substrate

sulfite [CPD:C00094];
hydrogen sulfide [CPD:C00283];
ferricytochrome c3 [CPD:C02682]

Product

thiosulfate [CPD:C00320];
ferrocytochrome c3 [CPD:C02684]

Comment

The enzyme is found in sulfate-reducing bacteria. The source of the electrons is molecular hydrogen, via EC 1.12.2.1, cytochrome-c3 hydrogenase. The organisms utilize the sulfite that is produced for energy generation by EC 1.8.99.5, dissimilatory sulfite reductase.

History

EC 1.8.2.5 created 2017

Reference

Authors

Ishimoto, M. and Koyama, J.

Title

On the role of a cytochrome in the thiosulfate reduction by sulfate-reducing bacterium.

Journal

B Chem Soc Jpn 28:231b-232 (1955)

Reference

Authors

Ishimoto, M., Toyama, J.

Title

Biochemical studies on sulfate reducing bacteria. VI. Separation of hydrogenase and thiosulfate reductase and partial purification of cytochrome and green pigment.

Journal

J Biochem (Tokyo) 44:233-242 (1957)

Reference

3 [PMID:5784203]

Authors

Nakatsukasa W, Akagi JM

Title

Thiosulfate reductase isolated from Desulfotomaculum nigrificans.

Journal

J Bacteriol 98:429-33 (1969)
DOI:10.1128/JB.98.2.429-433.1969

Reference

4 [PMID:5573735]

Authors

Haschke RH, Campbell LL

Title

Thiosulfate reductase of Desulfovibrio vulgaris.

Journal

J Bacteriol 106:603-7 (1971)
DOI:10.1128/JB.106.2.603-607.1971

Reference

5 [PMID:242299]

Authors

Hatchikian EC

Title

Purification and properties of thiosulfate reductase from Desulfovibrio gigas.

Journal

Arch Microbiol 105:249-56 (1975)
DOI:10.1007/bf00447143

Reference

6 [PMID:2993256]

Authors

Aketagawa J, Kobayashi K, Ishimoto M

Title

Purification and properties of thiosulfate reductase from Desulfovibrio vulgaris, Miyazaki F.

Journal

J Biochem 97:1025-32 (1985)
DOI:10.1093/oxfordjournals.jbchem.a135144

Other DBs

ExplorEnz - The Enzyme Database:

1.8.2.5

IUBMB Enzyme Nomenclature:

1.8.2.5

ExPASy - ENZYME nomenclature database:

1.8.2.5

BRENDA, the Enzyme Database:

1.8.2.5

All links

Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Protein sequence (1871)   
   UniProt (65)   
   RefSeq(pep) (1806)   
DNA sequence (20805)   
   RefSeq(nuc) (18336)   
   GenBank (1330)   
   EMBL (1139)   
All databases (22683)   

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