Entry
Name
thiocyanate desulfurase;
TcDH;
thiocyanate dehydrogenase
Class
Oxidoreductases;
Acting on a sulfur group of donors;
With a cytochrome as acceptor
BRITE hierarchy
Sysname
thiocyanate:cytochrome c oxidoreductase (cyanate and sulfur-forming)
Reaction(IUBMB)
thiocyanate + 2 ferricytochrome c + H2O = cyanate + sulfur + 2 ferrocytochrome c + 2 H+ [RN:
R12631 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme, characterized from the haloalkaliphilic sulfur-oxidizing bacterium Thioalkalivibrio paradoxus, contains three copper ions in its active site. It catalyses the direct conversion of thiocyanate into cyanate and elemental sulfur without involvement of molecular oxygen.
History
EC 1.8.2.7 created 2020
Orthology
K24299 thiocyanate desulfurase
Genes
» show all
Taxonomy
Reference
Authors
Tikhonova TV, Sorokin DY, Hagen WR, Khrenova MG, Muyzer G, Rakitina TV, Shabalin IG, Trofimov AA, Tsallagov SI, Popov VO
Title
Trinuclear copper biocatalytic center forms an active site of thiocyanate dehydrogenase.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.8.2.7
ExPASy - ENZYME nomenclature database: 1.8.2.7
BRENDA, the Enzyme Database: 1.8.2.7