KEGG   ENZYME: 1.8.4.4
Entry
EC 1.8.4.4                  Enzyme                                 
Name
glutathione---cystine transhydrogenase;
GSH-cystine transhydrogenase;
NADPH-dependent GSH-cystine transhydrogenase
Class
Oxidoreductases;
Acting on a sulfur group of donors;
With a disulfide as acceptor
Sysname
glutathione:cystine oxidoreductase
Reaction(IUBMB)
2 glutathione + cystine = glutathione disulfide + 2 cysteine [RN:R01109]
Reaction(KEGG)
R01109 > R01113
Substrate
glutathione [CPD:C00051];
cystine [CPD:C01420]
Product
glutathione disulfide [CPD:C00127];
cysteine [CPD:C00736]
History
EC 1.8.4.4 created 1972
Pathway
ec00270  Cysteine and methionine metabolism
ec00480  Glutathione metabolism
ec01100  Metabolic pathways
Reference
1  [PMID:5646485]
  Authors
Nagai S, Black S.
  Title
A thiol-disulfide transhydrogenase from yeast.
  Journal
J Biol Chem 243:1942-7 (1968)
Other DBs
ExplorEnz - The Enzyme Database: 1.8.4.4
IUBMB Enzyme Nomenclature: 1.8.4.4
ExPASy - ENZYME nomenclature database: 1.8.4.4
BRENDA, the Enzyme Database: 1.8.4.4
CAS: 37256-49-8

  All links  
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG REACTION (2)   
   KEGG RCLASS (1)   
DNA sequence (2)   
   GenBank (1)   
   EMBL (1)   
All databases (17)   

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