KEGG   ENZYME: 2.1.1.245
Entry
EC 2.1.1.245                Enzyme                                 
Name
5-methyltetrahydrosarcinapterin---corrinoid/iron-sulfur protein Co-methyltransferase;
cdhD (gene name);
cdhE (gene name)
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein methyltransferase
Reaction(IUBMB)
a [methyl-Co(III) corrinoid Fe-S protein] + tetrahydrosarcinapterin = a [Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrosarcinapterin [RN:R10385]
Reaction(KEGG)
R10385
Substrate
[methyl-Co(III) corrinoid Fe-S protein];
tetrahydrosarcinapterin [CPD:C18802]
Product
[Co(I) corrinoid Fe-S protein];
5-methyltetrahydrosarcinapterin [CPD:C18799]
Comment
Catalyses the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin. Forms, together with EC 1.2.7.4, anaerobic carbon-monoxide dehydrogenase, and EC 2.3.1.169, CO-methylating acetyl-CoA synthase, the acetyl-CoA decarbonylase/synthase complex that catalyses the demethylation of acetyl-CoA in a reaction that also forms CO2. This reaction is a key step in methanogenesis from acetate.
History
EC 2.1.1.245 created 2012
Orthology
K00194  acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta
K00197  acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma
Genes
DSF: UWK_03161
DLM: DPPLL_26580 DPPLL_26610
DAK: DaAHT2_0824
DBK: DGMP_17870 DGMP_17910
DDU: GF1_14220
ECOM: QTN59_00705(acsC)
DOL: Dole_3183 Dole_3186
DAL: Dalk_0679 Dalk_0682
DAT: HRM2_16650(cdhE) HRM2_16690(cdhD)
DTO: TOL2_C11800(cdhE) TOL2_C11830(cdhD)
DOV: DSCO28_59720 DSCO28_59750
DWD: DSCW_28510 DSCW_28540
DALK: DSCA_26700 DSCA_26730
DML: Dmul_30830(cdhD) Dmul_30860(cdhE)
DLI: dnl_32600(cdhE) dnl_32620(cdhD)
DMM: dnm_013290(cdhD) dnm_013340(cdhE)
DEK: DSLASN_16740 DSLASN_16770
DAO: Desac_1965 Desac_1968
DTI: Desti_0230 Desti_5164
SFU: Sfum_2564 Sfum_2567
DAX: FDQ92_06235 FDQ92_06250
DBR: Deba_0239 Deba_0243
DMP: FAK_42000 FAK_42030
TID: Thein_2182
TOP: TOPB45_0393
TCM: HL41_07620
THET: F1847_08570
CTHI: THC_1763
TAV: G4V39_01650
TMAI: FVE67_00225
DHR: LGS26_01910
CLJ: CLJU_c37570 CLJU_c37580
CAH: CAETHG_1610(acsC) CAETHG_1611(acsD)
CSQ: CSCA_4548 CSCA_4549
CACE: CACET_c10290(acsD) CACET_c10300(acsC)
CCK: Ccar_18795 Ccar_18800
CFM: BJL90_11120 BJL90_11125
CDRK: B9W14_22260 B9W14_22265
CLOS: DMR38_18730 DMR38_18735
RUM: CK1_12650 CK1_12660
RGV: NQ502_01490(acsC) NQ502_01495(acsD)
DSY: DSY1648 DSY1651
DHD: Dhaf_2793 Dhaf_2796
DDH: Desde_2251 Desde_2254
DDL: Desdi_1917 Desdi_1920
DMT: DESME_07335 DESME_07350
DOR: Desor_3269 Desor_3272
DAI: Desaci_2970 Desaci_2973
DMI: Desmer_2531 Desmer_2534
DED: DHBDCA_p226(acsC) DHBDCA_p227(acsD)
DEC: DCF50_p286(acsC) DCF50_p287(acsD)
DRS: DEHRE_00715 DEHRE_00720
PTH: PTH_1001(CdhE) PTH_1003(CdhD)
DAE: Dtox_1272 Dtox_1275
DKU: Desku_1488 Desku_1490
DAU: Daud_0112 Daud_0114 Daud_0872 Daud_0875
FWA: DCMF_05845 DCMF_05860
AACX: DEACI_2513 DEACI_2515
TJR: TherJR_1159 TherJR_1160
DGI: Desgi_2048 Desgi_2050
ELM: ELI_3605 ELI_3606
EMT: CPZ25_018690 CPZ25_018695
ELIM: B2M23_08385 B2M23_08390
AWO: Awo_c10710(acsD) Awo_c10720(acsC)
AWI: CHL1_002705 CHL1_002706
ALKA: J0B03_11250 J0B03_11255
CTHM: CFE_1662 CFE_1664
ROB: CK5_28660 CK5_28670
BYL: A4V09_05465 A4V09_05470
BHAN: CGC63_07960 CGC63_07965
BLAU: DQQ01_09715 DQQ01_09720
BPRO: PMF13cell1_04281(acsC) PMF13cell1_04282(acsD)
BLAB: EYS05_16715 EYS05_16720
BLIQ: INP51_05960 INP51_05965
BWX: NQ550_13500(acsC) NQ550_13505(acsD)
BMAS: LK422_06260 LK422_06265
BLAR: LC508_02770 LC508_02775
BLUI: Blut17040_19190(acsC) Blut17040_19200(acsD)
BCOC: BLCOC_33090(acsC) BLCOC_33100(acsD)
BHV: BLHYD_15420(acsD) BLHYD_15430(acsC)
QDO: H9Q78_01460 H9Q78_01465
WHJ: H9Q79_03160 H9Q79_03165
MFOR: NQ534_19155(acsD) NQ534_19160(acsC)
AMT: Amet_2025 Amet_2026
GFE: Gferi_06325 Gferi_06330
PBIF: KXZ80_13910 KXZ80_13915
PSOR: RSJ16_15720 RSJ16_15725
CDF: CD630_07250 CD630_07260
PDC: CDIF630_00841(acsD) CDIF630_00842(acsC)
CDC: CD196_0671 CD196_0672
CDL: CDR20291_0652 CDR20291_0653
PDF: CD630DERM_07250 CD630DERM_07260
ROC: HF520_11270 HF520_11275
TEM: JW646_10880 JW646_10885
TGC: L0P85_16875(acsC) L0P85_16880(acsD)
TMY: TEMA_26070(acsC) TEMA_26080(acsD)
TEB: T8CH_0658 T8CH_0659
THYR: P4S50_13880(acsC) P4S50_13885(acsD)
IBR: NQ514_13095(acsC) NQ514_13100(acsD)
CST: CLOST_1168 CLOST_1169
TKI: TKV_c19840(acsC) TKV_c19850(acsD)
CHY: CHY_1223(acsC) CHY_1226(acsD)
ADG: Adeg_0337 Adeg_0340
TPZ: Tph_c15140(acsD) Tph_c15160(acsC)
AAUT: ACETAC_10545 ACETAC_10550
MTA: Moth_1198 Moth_1201
MTHO: MOTHE_c11740(acsD) MOTHE_c11770(acsC1)
MTHZ: MOTHA_c12610(acsD) MOTHA_c12640(acsC1)
TEP: TepRe1_0558 TepRe1_0559
TAE: TepiRe1_0610(acsD) TepiRe1_0611(acsC)
BACG: D2962_12365 D2962_12370
TOC: Toce_0810 Toce_0811
NCD: ACONDI_02972(acsC_2) ACONDI_02973(acsD)
AAR: Acear_1300 Acear_1303
MANA: MAMMFC1_00472(acsD) MAMMFC1_00475(acsC)
STED: SPTER_13690(acsC) SPTER_13720(acsD)
CALK: HUE98_15610 HUE98_15615
DET: DET0665(acsC-1) DET0667(acsD-1) DET0699(acsC-2) DET0701(acsD-2)
DEH: cbdbA651(acsC) cbdbA654(acsD)
DEB: DehaBAV1_0634 DehaBAV1_0636
DEV: DhcVS_603(cdhE) DhcVS_605(cdhD)
DEG: DehalGT_0596 DehalGT_0598
DMC: btf_621(acsC) btf_623(acsD)
DMD: dcmb_667(acsC) dcmb_669(acsD)
DMG: GY50_0590(cdhE) GY50_0592(cdhD)
DMX: X792_03225 X792_03235
DMY: X793_02970 X793_02980
DMZ: X794_02720 X794_02730
DUC: UCH007_05830(acsC) UCH007_05850(acsD)
DLY: Dehly_0816 Dehly_0818
DEW: DGWBC_1387
DFO: Dform_00888(cdhE|acsC) Dform_00913(cdhD|acsD) Dform_00915(cdhE|acsC)
DETH: HX448_06195 HX448_06205
KST: KSMBR1_1320(acsD) KSMBR1_1323(acsC_1)
BROC: IPI25_11055 IPI25_11070
BPIT: BPIT_02190 BPIT_02230
JET: L3J17_07125 L3J17_07140
VAI: BU251_04950 BU251_04965
TPI: TREPR_3065 TREPR_3066
TAZ: TREAZ_1645 TREAZ_1647
TYE: THEYE_A1471 THEYE_A1472
DTP: JZK55_05460 JZK55_05470
MJA: MJ_0112 MJ_0113
MFE: Mefer_0823 Mefer_0824
MVU: Metvu_1052 Metvu_1053
MFS: MFS40622_0985 MFS40622_0986
MIF: Metin_1344 Metin_1345
MJH: JH146_0755 JH146_0756
MESG: MLAUSG7_0009(cdhD) MLAUSG7_0010(cdhE)
MESA: MLASG1_1026(cdhE) MLASG1_1027(cdhD)
MIG: Metig_1085 Metig_1086
MMP: MMP0980(cdh) MMP0981(cdhD)
MMQ: MmarC5_0800 MmarC5_0801
MMX: MmarC6_1677 MmarC6_1678
MMZ: MmarC7_0222 MmarC7_0223
MMD: GYY_05725 GYY_05730
MMAK: MMKA1_11360(cdhE) MMKA1_11370(cdhD)
MMAO: MMOS7_10720(cdhE) MMOS7_10730(cdhD)
MMAD: MMJJ_00100(acsD) MMJJ_00110(acsC)
MAE: Maeo_0210 Maeo_0211
MVN: Mevan_0306 Mevan_0307
MOK: Metok_0141 Metok_0142
METF: CFE53_01055(cdhD) CFE53_01060
MTH: MTH_1712 MTH_1713
MMG: MTBMA_c02910(cdhD) MTBMA_c02920(cdhE)
MWO: MWSIV6_0253(cdhD) MWSIV6_0254(cdhE)
METC: MTCT_1565 MTCT_1566
METE: tca_01659(acsD) tca_01660(acsC_2)
METK: FVF72_03100 FVF72_03105
MTHM: FZP57_01145 FZP57_01150
METJ: FZP68_06150 FZP68_06155
MARO: MarbSA_08760 MarbSA_08770
MEL: Metbo_0466 Metbo_0467
MEW: MSWAN_1929 MSWAN_1930
METH: MBMB1_1560(cdhE) MBMB1_1561(cdhD)
MFC: BRM9_0796(cdhE) BRM9_0797(cdhD)
MFI: DSM1535_0758(cdhE) DSM1535_0759(cdhD)
MCUB: MCBB_1816(cdhE) MCBB_1817(cdhD)
MSUB: BK009_06785 BK009_06790
METN: BK008_02430 BK008_02435
METT: CIT01_07290(cdhD) CIT01_07295
METO: CIT02_10140(cdhD) CIT02_10145
MEME: HYG87_07920 HYG87_07925
MFEG: GCM10025860_00980 GCM10025860_00990
MFV: Mfer_0522 Mfer_0523
MKA: MK0722(cdhD) MK0723(cdhE)
AFU: AF_0376 AF_0377
AFG: AFULGI_00003760 AFULGI_00003770
AVE: Arcve_1125 Arcve_1126
AST: Asulf_02024 Asulf_02025
FPL: Ferp_0735 Ferp_0736
GAC: GACE_0354 GACE_0355
GAH: GAH_01143 GAH_01144
MBA: Mbar_A0199 Mbar_A0200 Mbar_A0429 Mbar_A0430
MBY: MSBRM_0623 MSBRM_0624 MSBRM_2759 MSBRM_2760
MBW: MSBRW_0571 MSBRW_0572 MSBRW_0796 MSBRW_0797
MBAR: MSBR2_1755 MSBR2_1756 MSBR2_2717 MSBR2_2718
MBAK: MSBR3_2710 MSBR3_2711 MSBR3_2950 MSBR3_2951
MAC: MA_1011(cdhE) MA_1012(cdhD) MA_3864(cdhD) MA_3865(cdhE)
MMA: MM_0688 MM_0689 MM_2084 MM_2085
MMAZ: MmTuc01_2152 MmTuc01_2153
MMJ: MSMAS_0625 MSMAS_0626 MSMAS_2600 MSMAS_2601
MMAC: MSMAC_0627 MSMAC_0628 MSMAC_1818 MSMAC_1820
MVC: MSVAZ_0990 MSVAZ_0991 MSVAZ_3012 MSVAZ_3013
MEK: MSKOL_0962 MSKOL_0963 MSKOL_3024 MSKOL_3025
MLS: MSLAZ_0644 MSLAZ_0645
METM: MSMTP_0682 MSMTP_0683 MSMTP_0690 MSMTP_0691
MEF: MSWH1_0791 MSWH1_0792
MEQ: MSWHS_0843 MSWHS_0844
MSJ: MSSAC_3459 MSSAC_3460 MSSAC_3601 MSSAC_3602 MSSAC_3603
MSZ: MSSIH_2987 MSSIH_2988 MSSIH_3141 MSSIH_3142
MSW: MSSIT_3045 MSSIT_3046 MSSIT_3213 MSSIT_3214
MTHR: MSTHT_2335 MSTHT_2336
MTHE: MSTHC_0944 MSTHC_0945
MHOR: MSHOH_0734 MSHOH_0735 MSHOH_3264 MSHOH_3265
MFZ: AOB57_003755(cdhD) AOB57_003760
MBU: Mbur_0862 Mbur_0863
MMET: MCMEM_0994 MCMEM_0995
MELO: J7W08_03320(cdhD) J7W08_03325
MMH: Mmah_1170 Mmah_1171
MHAZ: BHR79_07680 BHR79_07685
MPOT: BKM01_03925 BKM01_03930
MEV: Metev_0421 Metev_0422
MZH: Mzhil_1132 Mzhil_1133
MPY: Mpsy_2890 Mpsy_2891
MZI: HWN40_08245(cdhD) HWN40_08250
MMAV: RE476_02145(cdhD) RE476_02150(acsC)
MSEB: RE474_12040(cdhD) RE474_12045(acsC)
MHZ: Metho_0979 Metho_0980
MEHF: MmiHf6_01240 MmiHf6_01250(acsC)
MEES: MmiEs2_08410 MmiEs2_08420(acsC)
MTP: Mthe_0287 Mthe_0288
MCJ: MCON_1325(cdhE) MCON_1326(cdhD)
MHI: Mhar_2322 Mhar_2323
MHU: Mhun_0686 Mhun_0687
MRTJ: KHC33_09845(cdhD) KHC33_09850
MBG: BN140_2373(acsC) BN140_2374(acsD)
MEMA: MMAB1_3159(acsC) MMAB1_3161
MCHK: MchiMG62_09120 MchiMG62_09130
MRC: R6Y96_05885 R6Y96_05890(acsC)
MFK: E2N92_11680 E2N92_11685
MBN: Mboo_1194 Mboo_1195 Mboo_1369 Mboo_1370
MFO: Metfor_1454 Metfor_1455 Metfor_1717 Metfor_1718
MPL: Mpal_0804 Mpal_0805
RCI: LRC461(cdhD) LRC463(cdhE)
MELU: MTLP_05390(cdhD) MTLP_05400
MER: MMINT_19120 MMINT_19130
BARC: AOA65_0450(cdhE1) AOA65_0451(cdhD)
BARB: AOA66_1431(cdhD) AOA66_1432(cdhE1)
LOB: NEF87_003955 NEF87_004234
 » show all
Reference
1  [PMID:8550451]
  Authors
Maupin-Furlow J, Ferry JG
  Title
Characterization of the cdhD and cdhE genes encoding subunits of the corrinoid/iron-sulfur enzyme of the CO dehydrogenase complex from Methanosarcina thermophila.
  Journal
J Bacteriol 178:340-6 (1996)
DOI:10.1128/JB.178.2.340-346.1996
  Sequence
[ag:AAA93168 AAA93167]
Reference
2  [PMID:8626532]
  Authors
Grahame DA, DeMoll E.
  Title
Partial reactions catalyzed by protein components of the acetyl-CoA decarbonylase synthase enzyme complex from Methanosarcina barkeri.
  Journal
J Biol Chem 271:8352-8 (1996)
DOI:10.1074/jbc.271.14.8352
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.245
IUBMB Enzyme Nomenclature: 2.1.1.245
ExPASy - ENZYME nomenclature database: 2.1.1.245
BRENDA, the Enzyme Database: 2.1.1.245

  All links  
Pathway (3)   
   KEGG MODULE (3)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (2243)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (531)   
   KEGG MGENES (1321)   
   RefGene (389)   
Protein sequence (672)   
   UniProt (663)   
   SWISS-PROT (9)   
DNA sequence (136)   
   GenBank (69)   
   EMBL (67)   
Protein domain (6)   
   InterPro (6)   
All databases (3067)   

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